Protein Overview: GstS1-PC, GstS1-...

General Information:
Name(s) found:	GstS1-PC / FBpp0099646 [FlyBase] GstS1-PA / FBpp0086157 [FlyBase] GstS1-PB / FBpp0086156 [FlyBase]
Description(s) found: Found 57 descriptions. SHOW ALL	The gene Glutathione S transferase S1 is referred to in FlyBase by the symbol Dmel\GstS1 (CG8938, FBgn0010226). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:12980758..12984935. It has the cytological map location 53F7-53F8. There is experimental evidence that it has the molecular function</span>: glutathione peroxidase activity; glutathione transferase activity. It is reported to be involved in the biological process</span>: response to oxidative stress. 53 alleles are reported. The phenotypes of these alleles are annotated with: eye; macrochaeta; wing. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase] The gene Glutathione S transferase S1 is referred to in FlyBase by the symbol Dmel\GstS1 (CG8938, FBgn0010226). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:12980758..12984935. It has the cytological map location 53F7-53F8. There is experimental evidence that it has the molecular function</span>: glutathione peroxidase activity; glutathione transferase activity. It is reported to be involved in the biological process</span>: response to oxidative stress. 53 alleles are reported. The phenotypes of these alleles are annotated with: eye; macrochaeta; wing. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase] The gene Glutathione S transferase S1 is referred to in FlyBase by the symbol Dmel\GstS1 (CG8938, FBgn0010226). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:12980758..12984935. It has the cytological map location 53F7-53F8. There is experimental evidence that it has the molecular function</span>: glutathione peroxidase activity; glutathione transferase activity. It is reported to be involved in the biological process</span>: response to oxidative stress. 53 alleles are reported. The phenotypes of these alleles are annotated with: eye; macrochaeta; wing. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	249 amino acids
Gene Ontology:
Cellular Component:	cellular_component [ND]
Biological Process:	response to oxidative stress [NAS]
Molecular Function:	glutathione peroxidase activity [IDA] glutathione transferase activity [IDA][ISS][NAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADEAQAPPA EGAPPAEGEA PPPAEGAEGA VEGGEAAPPA EPAEPIKHSY TLFYFNVKAL  60
   61 AEPLRYLFAY GNQEYEDVRV TRDEWPALKP TMPMGQMPVL EVDGKRVHQS ISMARFLAKT 120
  121 VGLCGATPWE DLQIDIVVDT INDFRLKIAV VSYEPEDEIK EKKLVTLNAE VIPFYLEKLE 180
  181 QTVKDNDGHL ALGKLTWADV YFAGITDYMN YMVKRDLLEP YPALRGVVDA VNALEPIKAW 240
  241 IEKRPVTEV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

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Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

Term	Confidence	Notes
glutathione transferase activity	4.50796867464992	bayes_pls_golite062009
prostaglandin-D synthase activity	3.77818075962089	bayes_pls_golite062009
glutathione binding	3.70571520983029	bayes_pls_golite062009
antioxidant activity	3.66884588063322	bayes_pls_golite062009
peroxidase activity	3.43831566988273	bayes_pls_golite062009
oxidoreductase activity, acting on peroxide as acceptor	3.43831566988273	bayes_pls_golite062009
glutathione peroxidase activity	2.56524997297011	bayes_pls_golite062009
selenium binding	2.55069860113032	bayes_pls_golite062009
peroxiredoxin activity	2.12777217096121	bayes_pls_golite062009
thioredoxin peroxidase activity	1.96134566495756	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors	1.8187537496904	bayes_pls_golite062009
disulfide oxidoreductase activity	1.32811008894503	bayes_pls_golite062009
binding	1.25802922431343	bayes_pls_golite062009
molecular transducer activity	1.03696928411308	bayes_pls_golite062009
signal transducer activity	1.03696928411308	bayes_pls_golite062009
phospholipid-hydroperoxide glutathione peroxidase activity	0.874146425427531	bayes_pls_golite062009
catalytic activity	0.672192331361968	bayes_pls_golite062009
transcription regulator activity	0.52671047749426	bayes_pls_golite062009
receptor binding	0.430107649265259	bayes_pls_golite062009
maleylacetoacetate isomerase activity	0.426921894831614	bayes_pls_golite062009
DNA binding	0.278017923256183	bayes_pls_golite062009
nucleic acid binding	0.27489371858599	bayes_pls_golite062009
protein binding	0.134341907247724	bayes_pls_golite062009
protein disulfide oxidoreductase activity	0.0719543694089202	bayes_pls_golite062009
transcription repressor activity	0.00678211696545472	bayes_pls_golite062009

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..249]	PSI-BLAST	37.045757	Class sigma GST

Protein Overview: GstS1-PC, GstS1-...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: