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View Structure Prediction Details

Protein: GstS1-PC, GstS1-...
Organism: Drosophila melanogaster
Length: 249 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GstS1-PC, GstS1-....

Description E-value Query
Range
Subject
Range
gi|76097697 - gi|76097697|gb|ABA39530.1| glutathione S-transferase [Solenopsis invicta]
171.0 [0..47] [249..1]
gi|2052029, gi|7... - pir||T07156 probable glutathione transferase (EC 2.5.1.18) - soybean, gi|2052029|emb|CAA71784.1| glu...
168.0 [0..50] [244..5]
gi|91079164 - gi|91079164|ref|XP_967406.1| PREDICTED: similar to putative glutathione s-transferase [Tribolium cas...
168.0 [0..30] [248..130]
gst-14 - glutathione S-transferase status:Partially_confirmed UniProt:Q93696 protein_id:CAB02289.1
164.0 [0..47] [249..1]
gi|39591186, gi|... - gi|39591186|emb|CAE73239.1| Hypothetical protein CBG20648 [Caenorhabditis briggsae], gi|187022944|em...
gi|157752456 - gi|157752456|ref|XP_001679940.1| Hypothetical protein CBG20648 [Caenorhabditis briggsae AF16]
164.0 [0..47] [248..1]
gi|157130284, gi... - gi|157130284|ref|XP_001661870.1| glutathione s-transferase [Aedes aegypti], gi|108871930|gb|EAT36155...
164.0 [0..45] [249..33]

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Predicted Domain #1
Region A:
Residues: [1-249]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADEAQAPPA EGAPPAEGEA PPPAEGAEGA VEGGEAAPPA EPAEPIKHSY TLFYFNVKAL  60
   61 AEPLRYLFAY GNQEYEDVRV TRDEWPALKP TMPMGQMPVL EVDGKRVHQS ISMARFLAKT 120
  121 VGLCGATPWE DLQIDIVVDT INDFRLKIAV VSYEPEDEIK EKKLVTLNAE VIPFYLEKLE 180
  181 QTVKDNDGHL ALGKLTWADV YFAGITDYMN YMVKRDLLEP YPALRGVVDA VNALEPIKAW 240
  241 IEKRPVTEV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 37.045757
Match: 1m0uA
Description: Class sigma GST
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
glutathione transferase activity 4.50796867464992 bayes_pls_golite062009
prostaglandin-D synthase activity 3.77818075962089 bayes_pls_golite062009
glutathione binding 3.70571520983029 bayes_pls_golite062009
antioxidant activity 3.66884588063322 bayes_pls_golite062009
peroxidase activity 3.43831566988273 bayes_pls_golite062009
oxidoreductase activity, acting on peroxide as acceptor 3.43831566988273 bayes_pls_golite062009
glutathione peroxidase activity 2.56524997297011 bayes_pls_golite062009
selenium binding 2.55069860113032 bayes_pls_golite062009
peroxiredoxin activity 2.12777217096121 bayes_pls_golite062009
thioredoxin peroxidase activity 1.96134566495756 bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors 1.8187537496904 bayes_pls_golite062009
disulfide oxidoreductase activity 1.32811008894503 bayes_pls_golite062009
binding 1.25802922431343 bayes_pls_golite062009
molecular transducer activity 1.03696928411308 bayes_pls_golite062009
signal transducer activity 1.03696928411308 bayes_pls_golite062009
phospholipid-hydroperoxide glutathione peroxidase activity 0.874146425427531 bayes_pls_golite062009
catalytic activity 0.672192331361968 bayes_pls_golite062009
transcription regulator activity 0.52671047749426 bayes_pls_golite062009
receptor binding 0.430107649265259 bayes_pls_golite062009
maleylacetoacetate isomerase activity 0.426921894831614 bayes_pls_golite062009
DNA binding 0.278017923256183 bayes_pls_golite062009
nucleic acid binding 0.27489371858599 bayes_pls_golite062009
protein binding 0.134341907247724 bayes_pls_golite062009
protein disulfide oxidoreductase activity 0.0719543694089202 bayes_pls_golite062009
transcription repressor activity 0.00678211696545472 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle