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Protein Overview: didum-PB

General Information:
Name(s) found: didum-PB / FBpp0088685 [FlyBase]
Description(s) found:
Found 19 descriptions.
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  • The gene dilute class unconventional myosin is referred to in FlyBase by the symbol Dmel\didum (CG2146, FBgn0261397). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:3387660..3396130. It has the cytological map location 43C7-43D1. There is experimental evidence that it has the molecular function</span>: actin binding; actin-dependent ATPase activity; ATP binding; myosin light chain binding. There is experimental evidence that it is involved in the biological process</span>: positive regulation of pole plasm oskar mRNA localization; sperm individualization; rhabdomere development; determination of anterior/posterior axis, embryo. 19 alleles are reported. The phenotypes of these alleles are annotated with: spermatid cyst; spermatozoon. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1196 amino acids

    Gene Ontology:
    Cellular Component: myosin complex [ISS]
    Biological Process: sperm individualization [IMP]
    anterior/posterior axis specification, embryo [IMP]
    [NOT]oogenesis [IMP]
    rhabdomere development [IMP]
    positive regulation of pole plasm oskar mRNA localization [IMP]
    Molecular Function: actin filament binding [IEA]
    ATP binding [IDA][ISS]
    actin-dependent ATPase activity [IDA]
    calmodulin binding [ISS]
    actin binding [IDA][ISS]
    myosin light chain binding [IPI]
    motor activity [ISS]
    ATPase activity, coupled [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSEEMLYAQ GAKIWVPHAD LVWESATLEE SYRKGAGFLK ICTDSGKLKE VKLKADGSDL  60
   61 PPLRNPAILV GQNDLTTLSY LHEPGVLHNL RVRFCERQII YTYCGIILVA INPYAEMPLY 120
  121 GPSIIRAYRG HAMGDLEPHI FALAEEAYTK LERENCNLSI IVSGESGAGK TVSAKYAMRY 180
  181 FAAVGGSESE TQVERKVLAS SPIMEAFGNA KTTRNDNSSR FGKFTKLLFR NQMGVMFLQG 240
  241 ATMHTYLLEK SRVVYQAQGE RNYHIFYQLC AARSKYPELV LDHQDKFQFL NMGGAPEIER 300
  301 VSDAEQFNET VQAMTVLGFS IQQIADIVKI LAGILHLGNI QVSKKFNEGS EEEDSDSCDI 360
  361 FHNDIHLQIT ADLLRVSADD LRRWLLMRKI ESVNEYVLIP NSIEAAQAAR DALAKHIYAK 420
  421 LFQYIVGVLN KSLNNGSKQC SFIGVLDIYG FETFEVNSFE QFCINYANEK LQQQFNQHVF 480
  481 KLEQEEYLKE GITWTMIDFY DNQPCIDLIE SRLGVLDLLD EECRMPKGSD ESWAGKLIGK 540
  541 CNKFPHFEKP RFGTTSFFIK HFSDTVEYDV NGFLEKNRDT VSKELTQVLS ESNMSLAKQV 600
  601 MTLEEIDTLC VDSAKSSTLG GRVVISAGRK QVVPSKQHRK TVGSQFQESL ASLISTLHAT 660
  661 TPHYVRCIKP NDDKVAFKWE TAKIIQQLRA CGVLETVRIS AAGFPSRWLY PDFYMRYQLL 720
  721 VYRSKLDKND MKLSCRNIVM KWIQDEDKYR FGNTQIFFRA GQVAFLEQVR ANLRKKYITI 780
  781 VQSVVRRFVY RRQFLRIQKV INGIQKHARG YLARERTQKM REARAGLILS KYARGWLCRR 840
  841 RYLRLRHSIS GIQTYARGML ARNKFHAMRD HYRAVQIQRF VRGALARRAY QKRRRNIIIC 900
  901 QAAIRRFLAR RKFKRMKAEA KTISHMENKY MGLENKIISM QQRIDELNRD NSNLKHKTSE 960
  961 ISVLKMKLEL KKTLEAEFKN VKAACQDKDK LIEALNKQLE AERDEKMQLL EENGHAQEEW1020
 1021 ISQKQTWRQE NEELRRQIDE IIDMAKNAEV NQRNQEDRML AEIDNRELNE AYQRAIKDKE1080
 1081 VIENENFMLK EELSRLTAGS FSLHARKASN ASSQNEDDVG YASAKNTLDI NRPPDLLSKN1140
 1141 YSYNDSTSLV VKLRSILEEE KQKHKVLQEQ YIKLSSRHKP TEDSFRTACR LAGRGT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..1056] PSI-BLAST 1000.0 No description for 2dfsA was found.
    2 View Details [1057..1196] PSI-BLAST 10.39794 No description for 2i1jA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.78

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle