Protein Overview: ed-PA, FBpp0306381

General Information:
Name(s) found:	FBpp0306381 [FlyBase] ed-PA / FBpp0077154 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|24581578\|ref\|NP_523469.2\| echinoid [Drosophila melanogaster] [NCBI NR] gi\|22953817\|gb\|AAF51045.2\| echinoid [Drosophila melanogaster] [NCBI NR] type=protein; loc=2L:join(4032676..4032769,4074514..4074712,4079504..4079764,4079826..4080022,4097850..4100039,4100622..4101128,4107436..4107804,4113621..4113802); ID=FBpp0306381; name=ed-PB; parent=FBgn0000547,FBtr0334265; dbxref=FlyBase:FBpp0306381,FlyBase_Annotation_IDs:CG12676-PB,REFSEQ:NP_001260013,GB_protein:AGB92549; MD5=b7839de9c946497736f32e973a96fce0; length=1332; release=r5.56; species=Dmel; [FlyBase] The gene echinoid is referred to in FlyBase by the symbol Dmel\ed (CG12676, FBgn0000547). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:4031379..4115059. It has the cytological map location 24D4-24D6. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence for 15 unique biological process</span> terms, many of which group under: anatomical structure development; organ morphogenesis; organ development; cell adhesion; regulation of developmental process; regulation of biological process; cell-cell adhesion; homophilic cell adhesion; regulation of neurogenesis; actin filament-based process; behavioral interaction between organisms; regulation of epidermal growth factor receptor signaling pathway. 60 alleles are reported. The phenotypes of these alleles are annotated with 29 unique terms, many of which group under: peripheral nervous system; external compound sense organ; nervous system; adult segment; adult mesothoracic segment; organ system; embryonic nervous system; compound cell cluster organ; embryonic segment; primordium. It has one annotated transcript and one annotated polypeptide. [FlyBase] >CG12676-PA translation from_gene[CG12676 ed FBgn0000547] seq_release:3 mol_weight=146498 cds_boundaries:(2L:4,025,245..4,106,368[+]) aa_length:1332 transcript_info:[CG12676-RA seq_release:3] gene_info:[gene symbol:ed synonyms:[CG16842 CG15424] FBgn000 [hmr_yeast5_DM3-1_pombe.fasta] (Q9VQW7) CG12676 protein [DrosMelano7227.FASTAC.txt] CG12676-PA [Drosophila melanogaster]gi\|24581578\|ref\|NP_523469.2\| CG12676-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=2L:join(4032676..4032769,4074514..4074712,4079504..4079764,4079826..4080022,4097850..4100039,4100622..4101128,4107436..4107804,4113621..4113802); ID=FBpp0077154; name=ed-PA; parent=FBgn0000547,FBtr0077465; dbxref=FlyBase:FBpp0077154,FlyB [fly-100309-contam.fasta] CG12676-PA [Drosophila melanogaster] [nr-271106-contam.fasta] echinoid CG12676-PA [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=2L:join(4032676..4032769,4074514..4074712,4079504..4079764,4079826..4080022,4097850..4100039,4100622..4101128,4107436..4107804,4113621..4113802); ID=FBpp0077154; name=ed-PA; parent=FBgn0000547,FBtr0077465; dbxref=FlyBase:FBpp0077154,FlyBase_Annotation_IDs:CG12676-PA,GB_protein:AAF51045.2,REFSEQ:NP_523469,GB_protein:AAF51045; MD5=b7839de9c946497736f32e973a96fce0; length=1332; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=2L:join(4032676..4032769,4074514..4074712,4079504..4079764,4079826..4080022,4097850..4100039,4100622..4101128,4107436..4107804,4113621..4113802); ID=FBpp0077154; name=ed-PA; parent=FBgn0000547,FBtr0077465; dbxref=FlyBase:FBpp0077154,FlyBase_Annotation_IDs:CG12676-PA,GB_protein:AAF51045.2,REFSEQ:NP_523469,GB_protein:AAF51045; MD5=b7839de9c946497736f32e973a96fce0; length=1332; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] Echinoid OS=Drosophila melanogaster GN=ed PE=1 SV=2 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=2L:join(4032676..4032769,4074514..4074712,4079504..4079764,4079826..4080022,4097850..4100039,4100622..4101128,4107436..4107804,4113621..4113802); ID=FBpp0077154; name=ed-PA; parent=FBgn0000547,FBtr0077465; dbxref=FlyBase:FBpp0077154,FlyBase_Annotation_IDs:CG12676-PA,GB_protein:AAF51045.2,REFSEQ:NP_523469,GB_protein:AAF51045,FlyMine:FBpp0077154,modMine:FBpp0077154; MD5=b7839de9c946497736f32e973a96fce0; length=1332; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] Echinoid OS=Drosophila melanogaster GN=ed PE=2 SV=2 [UniProt_D_Melanogaster_07132012_07-13-2012_reversed.fasta] type=protein; loc=2L:join(4032676..4032769,4074514..4074712,4079504..4079764,4079826..4080022,4097850..4100039,4100622..4101128,4107436..4107804,4113621..4113802); ID=FBpp0077154; name=ed-PA; parent=FBgn0000547,FBtr0077465; dbxref=FlyBase:FBpp0077154,FlyBase_Annotation_IDs:CG12676-PA,GB_protein:AAF51045.2,REFSEQ:NP_523469,GB_protein:AAF51045,FlyMine:FBpp0077154,modMine:FBpp0077154; MD5=b7839de9c946497736f32e973a96fce0; length=1332; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=2L:join(4032676..4032769,4074514..4074712,4079504..4079764,4079826..4080022,4097850..4100039,4100622..4101128,4107436..4107804,4113621..4113802); ID=FBpp0306381; name=ed-PB; parent=FBgn0000547,FBtr0334265; dbxref=FlyBase:FBpp0306381,FlyBase_Annotation_IDs:CG12676-PB,REFSEQ:NP_001260013,GB_protein:AGB92549; MD5=b7839de9c946497736f32e973a96fce0; length=1332; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=2L:join(4032676..4032769,4074514..4074712,4079504..4079764,4079826..4080022,4097850..4100039,4100622..4101128,4107436..4107804,4113621..4113802); ID=FBpp0077154; name=ed-PA; parent=FBgn0000547,FBtr0077465; dbxref=FlyBase:FBpp0077154,FlyBase_Annotation_IDs:CG12676-PA,GB_protein:AAF51045.2,REFSEQ:NP_523469,GB_protein:AAF51045,FlyMine:FBpp0077154,modMine:FBpp0077154; MD5=b7839de9c946497736f32e973a96fce0; length=1332; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] type=protein; loc=2L:join(4032676..4032769,4074514..4074712,4079504..4079764,4079826..4080022,4097850..4100039,4100622..4101128,4107436..4107804,4113621..4113802); ID=FBpp0306381; name=ed-PB; parent=FBgn0000547,FBtr0334265; dbxref=FlyBase:FBpp0306381,FlyBase_Annotation_IDs:CG12676-PB,REFSEQ:NP_001260013,GB_protein:AGB92549; MD5=b7839de9c946497736f32e973a96fce0; length=1332; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] Echinoid, isoform A OS=Drosophila melanogaster GN=ed PE=1 SV=2 [DROME.fasta.20160308] FBpp0077154 type=protein; loc=2L:join(4032676..4032769,4074514..4074712,4079504..4079764,4079826..4080022,4097850..4100039,4100622..4101128,4107436..4107804,4113621..4113802); ID=FBpp0077154; name=ed-PA; parent=FBgn0000547,FBtr0077465; dbxref=FlyBase:FBpp0077154,FlyBase_Annotation_IDs:CG12676-PA,GB_protein:AAF51045.2,REFSEQ:NP_523469,GB_protein:AAF51045,FlyMine:FBpp0077154,modMine:FBpp0077154; MD5=b7839de9c946497736f32e973a96fce0; length=1332; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] FBpp0306381 type=protein; loc=2L:join(4032676..4032769,4074514..4074712,4079504..4079764,4079826..4080022,4097850..4100039,4100622..4101128,4107436..4107804,4113621..4113802); ID=FBpp0306381; name=ed-PB; parent=FBgn0000547,FBtr0334265; dbxref=FlyBase:FBpp0306381,FlyBase_Annotation_IDs:CG12676-PB,REFSEQ:NP_001260013,GB_protein:AGB92549; MD5=b7839de9c946497736f32e973a96fce0; length=1332; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=2L:join(4032676..4032769,4074514..4074712,4079504..4079764,4079826..4080022,4097850..4100039,4100622..4101128,4107436..4107804,4113621..4113802); ID=FBpp0077154; name=ed-PA; parent=FBgn0000547,FBtr0077465; dbxref=FlyBase:FBpp0077154,FlyBase_Annotation_IDs:CG12676-PA,GB_protein:AAF51045.2,REFSEQ:NP_523469,GB_protein:AAF51045,UniProt/TrEMBL:Q9VQW7,FlyMine:FBpp0077154,modMine:FBpp0077154; MD5=b7839de9c946497736f32e973a96fce0; length=1332; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta] type=protein; loc=2L:join(4032676..4032769,4074514..4074712,4079504..4079764,4079826..4080022,4097850..4100039,4100622..4101128,4107436..4107804,4113621..4113802); ID=FBpp0306381; name=ed-PB; parent=FBgn0000547,FBtr0334265; dbxref=FlyBase:FBpp0306381,FlyBase_Annotation_IDs:CG12676-PB,REFSEQ:NP_001260013,GB_protein:AGB92549,UniProt/TrEMBL:Q9VQW7; MD5=b7839de9c946497736f32e973a96fce0; length=1332; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	1332 amino acids
Gene Ontology:
Cellular Component:	cell-cell adherens junction [IDA] integral to membrane [ISS] plasma membrane [IDA]
Biological Process:	regulation of cell shape [IMP] cell-cell adhesion [IMP] dorsal closure [IMP] mushroom body development [IMP] epidermal growth factor receptor signaling pathway [IMP][IPI] imaginal disc-derived wing morphogenesis [IMP] dorsal appendage formation [IMP] cell adhesion [ISS] homophilic cell adhesion [IDA][IMP] muscle organ morphogenesis [IMP] negative regulation of epidermal growth factor receptor signaling pathway [IGI][IMP][NAS] inter-male aggressive behavior [IMP] sensory organ development [IMP] morphogenesis of an epithelium [IMP] negative regulation of neurogenesis [IMP] contractile actin filament bundle assembly [IMP]
Molecular Function:	protein binding [IPI]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRRKTTTKGT AIVNSRSARR AATTICNFFL IALVALSSTT LADESIDTRE NADLTLKCRF  60
   61 NDKYEANDFS FFWTRWTANP AQFDNVAIGE VQLSSGYRLD FQPERGIYDL QIKNVSYNRD 120
  121 NGRFECRIKA KGTGADVHQE FHNLTVLTPP HPPVISPGNI AVATEDKPME LTCSSIGGSP 180
  181 DPTITWYREG SNTPLPATVL KGGTKDQPTN ATLSIIPRRE DDGAKYKCVV RNRAMNEGKR 240
  241 LEATATLNVN YYPRVEVGPE NPLRVERDRT AKLECNVDAK PKVPNVRWNR NGRFISSSLV 300
  301 HTIHRVSVQD AGKYTCIADN GLGKTGEQEL ILDILYPPMV VIESKTREAE EGDTVTIRCN 360
  361 VTANPAPVTI EWLKENSPDF RYNGDVLTLT SVRADHAGNY ICRAVNIMQS QGMERSERVG 420
  421 NSTVALLVRH RPGQAYITPN KPVVHVGNGV TLTCSANPPG WPVPQYRWFR DMDGEFSSTQ 480
  481 KILAQGPQYS IPKAHLGNEG KYHCHAVNEL GIGMMATIVL EIHQPPQFLA KLQQHMTRRV 540
  541 ADTDYTVTCS AKGKPAPSVK WLKDAVEILP EENLYEVQTN PDQGLNGMVT VQSQLKFRGK 600
  601 ARPNGNALVP GDRGLYTCLY QNEVNSANSS MQLRIEHEPI VLHQYNKVAF DIRETAEVVC 660
  661 KVQAYPKPEF QWQFGNNPSP LTMSSDGHYE ISTTTDNNDI YTSVLKINSL THSDYGEYTC 720
  721 RVANTLDTIR APIRLQQKGP PEKPTNLRAT EVGHNYVSLS WDPGFDGGLS KTKFFVSYRR 780
  781 VAMPREEQLI PDCATLANSN SAWVEVDCQR DIPCKVTALE QHQSYAFKVK ALNPKSDSPY 840
  841 SSEIMVTTKV SRIPPPLQVT YEPNTRTLGI DVGATCLNLV AVVESMVNAD SPMAAWEVVT 900
  901 TMDNLQLSGN GPTHKEKIID RIIGARRVGG GRALGHTISE DEDDNGLNSL ALEDENSPTV 960
  961 RVKLCLRTNP EHCGDYTDAE IGRPYIAEAN ALATPTLIAI IVSCVVFALF AGLILMFCRC1020
 1021 KRNQSKKSAA AKDYEMDSVR PSIVAAQQNQ APPPYYPASG LDNKALEHSM DLALSMEDQK1080
 1081 TALYATQNGY SYHPGSGVVG VGMGGGVVGV GVGGSVVSGM GGGVGGIGGS GVGVNGIPGL1140
 1141 SAHTMPGNEW VNMGYMENNY SNSNNGGSVN SQDSLWQVKM SAAAVGNQQG MVQAPMNQYV1200
 1201 EQQPAYGYDP LTHGGYGAVD DYAPYPHLTA TPSQVGDEYH NLRNSQNPSR QDYCSDPYAS1260
 1261 VQKPKKRVDQ HLDSPYHDVS GLPNPYNMEH LEQDEVLPPQ QHMSLSYDDS FEGEYSTTPN1320
 1321 ARNRRVIREI IV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: ed-PA, FBpp0306381

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: