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The series of molecular signals generated as a consequence of an epidermal growth factor receptor binding to the ligand Gurken. The series of molecular signals generated as a consequence of an epidermal growth factor receptor binding to one of its physiological ligands. Any process that activates or increases the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity. The proteolysis of epidermal growth factor after its internalization via binding to its receptor. The series of molecular signals generated as a consequence of a epidermal growth factor receptor binding to one of its physiological ligands that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain. The process whereby a signal is passed from the epidermal growth factor receptor (EGFR) to components of the MAPKKK cascade, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell. Any process that stops, prevents or reduces the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity. The series of molecular signals generated as a consequence of an epidermal growth factor-type receptor binding to one of its physiological ligands. This process contributes to lung development. The series of molecular signals generated as a consequence of a transmembrane receptor tyrosine kinase binding to its physiological ligand. Any process that modulates the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity. Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell, where the receptor possesses catalytic activity or is closely associated with an enzyme such as a protein kinase.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: epidermal growth factor receptor signaling pathway
Acc: GO:0007173
Aspect: Biological Process
Desc: The series of molecular signals generated as a consequence of an epidermal growth factor receptor binding to one of its physiological ligands.
Synonyms:
  • EGFR signaling pathway
  • epidermal growth factor receptor signalling pathway
  • EGF receptor signalling pathway
  • EGF receptor signaling pathway
Proteins in PDR annotated with:
   This term: 102 [Search]
   Term or descendants: 165 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0007173 - epidermal growth factor receptor signaling pathway (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle