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Protein Overview: MYO5A_RAT

General Information:
Name(s) found: MYO5A_RAT [Swiss-Prot]
Description(s) found:
Found 21 descriptions.
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  • Unconventional myosin-Va OS=Rattus norvegicus GN=Myo5a PE=1 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 1828 amino acids

    Gene Ontology:
    Cellular Component: myosin complex [UNKNOWN][IEA]
    synaptic vesicle [IDA]
    secretory granule [UNKNOWN][IDA][TAS]
    Golgi apparatus [UNKNOWN]
    intermediate filament [UNKNOWN]
    actomyosin [UNKNOWN]
    neuronal cell body [UNKNOWN][IDA]
    actomyosin, myosin complex part [IDA]
    neuron projection [IDA]
    photoreceptor outer segment [UNKNOWN]
    cytoplasm [UNKNOWN][IDA]
    melanosome [UNKNOWN]
    ruffle [UNKNOWN]
    axon [IDA]
    Biological Process: melanin biosynthetic process [UNKNOWN]
    long-chain fatty acid biosynthetic process [UNKNOWN]
    insulin secretion [UNKNOWN]
    secretory granule localization [UNKNOWN][IDA][IMP]
    melanin metabolic process [UNKNOWN]
    vesicle transport along actin filament [IMP]
    synapse organization [UNKNOWN]
    synaptic transmission [UNKNOWN]
    myelination [UNKNOWN]
    anagen [UNKNOWN]
    odontogenesis [UNKNOWN]
    visual perception [UNKNOWN]
    exocytosis [UNKNOWN]
    developmental pigmentation [UNKNOWN]
    ER localization [UNKNOWN]
    melanocyte differentiation [UNKNOWN]
    locomotion involved in locomotory behavior [UNKNOWN]
    pigmentation [UNKNOWN][IMP]
    regulation of inositol-1,4,5-triphosphate receptor activity [UNKNOWN]
    melanosome localization [UNKNOWN]
    regulation of exocytosis [IMP]
    actin filament-based movement [UNKNOWN][IDA]
    neuromuscular process controlling balance [UNKNOWN]
    melanosome transport [UNKNOWN]
    Molecular Function: calcium-dependent protein binding [IPI]
    protein dimerization activity [IMP]
    SNARE binding [IPI]
    microfilament motor activity [UNKNOWN][IDA]
    ATP-dependent protein binding [IPI]
    motor activity [UNKNOWN][IEA][IMP]
    nucleotide binding [IEA]
    actin filament binding [IEA]
    ATP binding [IDA][IEA]
    calmodulin binding [UNKNOWN][IEA]
    protein binding [UNKNOWN][IEA]
    actin binding [UNKNOWN]
    protein heterodimerization activity [IDA]
    calcium ion binding [UNKNOWN]
    syntaxin-1 binding [IPI]
    microtubule plus-end binding [UNKNOWN]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAASELYTKF ARVWIPDPEE VWKSAELLKD YKPGDKVLLL HLEEGKDLEY RLDPKTSELP  60
   61 HLRNPDILVG ENDLTALSYL HEPAVLHNLR VRFIDSKLIY TYCGIVLVAI NPYEQLPIYG 120
  121 EDIINAYSGQ NMGDMDPHIF AVAEEAYKQM ARDERNQSII VSGESGAGKT VSAKYAMRYF 180
  181 ATVSGSASEA NVEEKVLASN PIMESIGNAK TTRNDNSSRF GKYIEIGFDK RYRIIGANMR 240
  241 TYLLEKSRVV FQAEEERNYH IFYQLCASAK LPEFKMLRLG NADSFHYTKQ GGSPMIEGVD 300
  301 DAKEMAHTRQ ACTLLGISES YQMGIFRILA GILHLGNVGF ASRDSDSCTI PPKHEPLIIF 360
  361 CDLMGVDYEE MCHWLCHRKL ATATETYIKP ISKLQATNAR DALAKHIYAK LFNWIVGHVN 420
  421 QALHSAVKQH SFIGVLDIYG FETFEINSFE QFCINYANEK LQQQFNMHVF KLEQEEYMKE 480
  481 QIPWTLIDFY DNQPCINLIE SKLGILDLLD EECKMPKGTD DTWAQKLYNT HLNKCALFEK 540
  541 PRMSNKAFII KHFADKVEYQ CEGFLEKNKD TVFEEQIKVL KSSKFKMLPE LFQDDEKAIS 600
  601 PTSATSSGRT PLTRVPVKPT KGRPGQTAKE HKKTVGLQFR NSLHLLMETL NATTPHYVRC 660
  661 IKPNDFKFPF TFDEKRAVQQ LRACGVLETI RISAAGFPSR WTYQEFFSRY RVLMKQKDVL 720
  721 GDRKQTCQNV LEKLILDKDK YQFGKTKIFF RAGQVAYLEK LRADKLRAAC IRIQKTIRGW 780
  781 LLRKRYLCMQ RAAITVQRYV RGYQARCYAK FLRRTKAATT IQKYWRMYVV RRKYKIRRAA 840
  841 TIVLQSYLRG YLARNRYRKI LREHKAVIIQ KRVRGWLART HYKRTMKAII YLQCCFRRMM 900
  901 AKRELKKLKI EARSVERYKK LHIGMENKIM QLQRKVDEQN KDYKCLMEKL TNLEGVYNSE 960
  961 TEKLRNDVER LQLSEEEAKV ATGRVLSLQE EIAKLRKDLE QTRSEKKSIE ERADKYKQET1020
 1021 EQLVSNLKEE NTLLKQEKET LNHLMVEQAK EMTETMERKL VEETKQLELD LNDERLRYQN1080
 1081 LLNEFSRLEE RYDDLKEEMT LMLNVPKPGH KRTDSTHSSN ESEYTFSSEF AETEDIAPRT1140
 1141 EEPTEKKVPL DMSLFLKLQK RVTELGQEKQ LMQDELDRKE EQVLRSKAKG GERPQIRGAE1200
 1201 LGYESLKRQE LESENKKLKN ELNELRKALS EKSAPEVNAP GAPAYRVLME QLTAVSEELD1260
 1261 VRKEEVLILR SQLVSQKEAI QPKDDKNTMT DSTILLEDVQ KMKDKGEIAQ AYIGLKETNR1320
 1321 LLESQLQSQK RSHENEAEAL RGEIQSLKEE NNRQQQLLAQ NLQLPPEARI EASLQHEITR1380
 1381 LTNENLDLME QLEKQDKTVR KLKKQLKVFA KKIGELEVGQ MENISPGQII DEPIRPVNIP1440
 1441 RKGKDFQGML EYKREDEQKL VKNLILELKP RGVAVNLISG LPAYILFMCV RHADYLDDDQ1500
 1501 KVRSLLTSTI NSIKKVLKKR GDDFETVSFW LSNTCRFLHC LKQYSGEEGF MKHNTSRQNE1560
 1561 HCLTNFDLAE YRQVLSDLAI QIYQQLVRVL ENILQPMIVS GMLEHETIQG VSGVKPTGLR1620
 1621 KRTSSIADEG TYTLDSILRQ LNSFHSVMCQ HGMDPELIKQ VVKQMFYIVG AITLNNLLLR1680
 1681 KDMCSWSKGM QIRYNVSQLE EWLRDKNLMN SGAKETLEPL IQAAQLLQVK KKTDDDAEAI1740
 1741 CSMCNALTTA QIVKVLNLYT PVNEFEERVS VSFIRTIQVR LRDRKDSPQL LMDAKHIFPV1800
 1801 TFPFNPSSLA LETIQIPASL GLGFIARV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.87

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle