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Protein Overview: ARGI1_RAT

General Information:
Name(s) found: ARGI1_RAT [Swiss-Prot]
Description(s) found:
Found 48 descriptions.
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  • Arginase-1 OS=Rattus norvegicus GN=Arg1 PE=1 SV=2 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 323 amino acids

    Gene Ontology:
    Cellular Component: extracellular space [IDA]
    cytoplasm [IEA]
    Biological Process: arginine metabolic process [IDA]
    urea cycle [IDA]
    response to wounding [IEP]
    female pregnancy [IEP]
    Molecular Function: metal ion binding [IEA]
    arginase activity [UNKNOWN][IDA]
    hydrolase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSKPKPIEI IGAPFSKGQP RGGVEKGPAA LRKAGLVEKL KETEYNVRDH GDLAFVDVPN  60
   61 DSPFQIVKNP RSVGKANEQL AAVVAETQKN GTISVVLGGD HSMAIGSISG HARVHPDLCV 120
  121 IWVDAHTDIN TPLTTSSGNL HGQPVAFLLK ELKGKFPDVP GFSWVTPCIS AKDIVYIGLR 180
  181 DVDPGEHYII KTLGIKYFSM TEVDKLGIGK VMEETFSYLL GRKKRPIHLS FDVDGLDPVF 240
  241 TPATGTPVVG GLSYREGLYI TEEIYKTGLL SGLDIMEVNP TLGKTPEEVT RTVNTAVALT 300
  301 LSCFGTKREG NHKPETDYLK PPK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..323] PSI-BLAST 101.0 Arginase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • arginase activity
    		•  6.53441421234691 bayes_pls_golite062009
  • agmatinase activity
    		•  3.73238467801147 bayes_pls_golite062009
  • protein deacetylase activity
    		•  3.15425266272734 bayes_pls_golite062009
  • histone deacetylase activity
    		•  3.10913119405575 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.52770743634098 bayes_pls_golite062009
  • hydrolase activity
    		•  2.11707868768295 bayes_pls_golite062009
  • transcription factor binding
    		•  2.06538836131829 bayes_pls_golite062009
  • binding
    		•  1.948738669065 bayes_pls_golite062009
  • deacetylase activity
    		•  1.91016771390707 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
    		•  1.72243397396987 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.70671280294121 bayes_pls_golite062009
  • catalytic activity
    		•  1.68836803454021 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.59562744871718 bayes_pls_golite062009
  • DNA binding
    		•  1.55288325159263 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
    		•  1.01223037319069 bayes_pls_golite062009
  • transcription factor activity
    		•  0.882841288306625 bayes_pls_golite062009
  • protein binding
    		•  0.725535842743004 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.68008378742866 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.52929003055123 bayes_pls_golite062009
  • enzyme binding
    		•  0.39566582482721 bayes_pls_golite062009
  • specific transcriptional repressor activity
    		•  0.38389503761392 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
    		•  0.0917282383800223 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle