General Information: |
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Name(s) found: |
NEDD4_RAT
[Swiss-Prot]
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Description(s) found:
SHOW ONLY BEST |
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Organism: | Rattus norvegicus |
Length: | 887 amino acids |
Gene Ontology: |
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Cellular Component: |
membrane fraction
[UNKNOWN]
perinuclear region of cytoplasm [UNKNOWN] ubiquitin ligase complex [UNKNOWN] cytoplasm [UNKNOWN][IEA] microvillus [IDA] cell cortex [UNKNOWN] membrane raft [IDA] cytosol [UNKNOWN] chromatin [UNKNOWN] intracellular [IEA] plasma membrane [UNKNOWN] |
Biological Process: |
glucocorticoid receptor signaling pathway
[UNKNOWN]
positive regulation of phosphoinositide 3-kinase cascade [UNKNOWN] neuron projection development [UNKNOWN] lysosomal transport [UNKNOWN] protein modification process [IEA] positive regulation of protein catabolic process [UNKNOWN] protein targeting to lysosome [UNKNOWN] positive regulation of nucleocytoplasmic transport [UNKNOWN] protein ubiquitination during ubiquitin-dependent protein catabolic process [UNKNOWN] receptor catabolic process [UNKNOWN] immune response [IEP] negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage [UNKNOWN] transmission of virus [UNKNOWN] development during symbiotic interaction [UNKNOWN] negative regulation of vascular endothelial growth factor receptor signaling pathway [ISS] cellular response to UV [UNKNOWN] progesterone receptor signaling pathway [UNKNOWN] negative regulation of sodium ion transport [UNKNOWN] receptor internalization [UNKNOWN] protein ubiquitination [UNKNOWN] |
Molecular Function: |
sodium channel regulator activity
[IPI]
RNA polymerase binding [UNKNOWN] ubiquitin-protein ligase activity [UNKNOWN] proline-rich region binding [UNKNOWN] protein domain specific binding [UNKNOWN] protein binding [UNKNOWN][IDA][IEA] ubiquitin binding [UNKNOWN] protein C-terminus binding [IDA][IPI] sodium channel inhibitor activity [UNKNOWN] acid-amino acid ligase activity [IEA] ligase activity [IEA] beta-2 adrenergic receptor binding [UNKNOWN] |
Sequence: |
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Sequence: [PDR BLAST] [ProtParam] |
1 11 21 31 41 51 | | | | | | 1 MAADDTEAPV LSEDEVWEFC LDKNEEGGGS PGSDVTDTCE PPCGCWELNP SSLEEEHVLF 60 61 TAESIISSFN NDDTRVVRVK VIAGIGLAKK DILGASDPYV RVTLYDPMSG VLTSVQTKTI 120 121 KKSLNPKWNE EILFRVLPQQ HRILFEVFDE NRLTRDDFLG QVDVPLYPLP TENPRMERPY 180 181 TFKDFVLHPR SHKSRVKGYL RLKMTYLPKN GSDDENADQA EELEPGWVVL DQPDAATHLQ 240 241 HPPEPSPLPP GWEERQDVLG RTYYVNHESR TTQWKRPSPE DDLTDDENGD IQLQAHGAFT 300 301 TRRQISEDVD GPDNHESPEN WEIVREDENT IYSGQAVQSP PSGHPDVQVR LAEELDTRLT 360 361 MYGNPATSQP VTSSNHSSRG GSSQTCIFEE QPTLPVLLPT SSGLPPGWEE KQDDRGRSYY 420 421 VDHNSKTTTW SKPTMQDDPR SKIPAHLRGK TPVDSNDLGP LPPGWEERTH TDGRVFFINH 480 481 NIKKTQWEDP RMQNVAITGP AEPYSRDYKR KYEFFRRKLK KQTDIPNKFE MKLRRANILE 540 541 DSYRRIMGVK RADFLKARLW IEFDGEKGLD YGGVAREWFF LISKEMFNPY YGLFEYSATE 600 601 DNYTLQINPN SGLCNEDHLS YFKFIGRVAG MAVYHGKLLD GFFIRPFYKM MLQKLITLHD 660 661 MESVDSEYYS SLRWILENDP TELDLRFIID EELFGQTHQH ELKTGGSEVV VTNKNKKEYI 720 721 YLVIQWRFVN RIQKQMAAFK EGFFELIPQD LIKIFDENEL ELLMCGLGDV DVNDWREHTK 780 781 YKNGYSLNHQ VIHWFWKAVL MMDSEKRIRL LQFVTGTSRV PMNGFAELYG SNGPQSFTVE 840 841 QWGTPDKLPR AHTCFNRLDL PPYESFDELW DKLQMAIENT QGFDGVD |
NOT SHOWING SINGLE HITS. [ Show Single Hits ]
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Protein predicted to be: | GLOBULAR (No transmembrane regions or signal peptide) |
Confidence of classification: | 0.99 |
Source: Reynolds et al. (2008)