Protein Overview: CD28_RAT

General Information:
Name(s) found:	CD28_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|6978625\|ref\|NP_037253.1\| Cd28 molecule [Rattus norvegicus] [NCBI NR] gi\|55906\|emb\|CAA39003.1\| CD28 [Rattus norvegicus] [NCBI NR] gi\|399210\|sp\|P31042.1\|CD28_RAT RecName: Full=T-cell-specific surface glycoprotein CD28; AltName: CD_antigen=CD28; Flags: Precursor [NCBI NR] T-cell-specific surface glycoprotein CD28 OS=Rattus norvegicus GN=Cd28 PE=2 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):9-65032997 T-cell-specific surface glycoprotein CD28 precursor [hmr_yeast5_DM3-1_pombe.fasta] CD28 antigen [HMR_022704-rand.fasta] CD28 antigen [Rattus norvegicus]gi\|55906\|emb\|CAA39003.1\| CD28 [Rattus norvegicus]gi\|399210\|sp\|P31042\|CD28_RAT T-cell-specific surface glycoprotein CD28 precursor [nrdb_11152004_Chlamydomonas] Tax_Id=10116 T-cell-specific surface glycoprotein CD28 precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_013121) CD28 antigen [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Cd28 molecule [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] T-cell-specific surface glycoprotein CD28 precursor [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] CD28 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 T-CELL-SPECIFIC SURFACE GLYCOPROTEIN CD28 PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] CD28 antigen [Rattus norvegicus] [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Cd28 T-cell-specific surface glycoprotein CD28 [rat-ipi-250309-contam.fasta] T-cell-specific surface glycoprotein CD28 OS=Rattus norvegicus GN=Cd28 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	218 amino acids
Gene Ontology:
Cellular Component:	membrane [IEA] membrane raft [IDA] external side of plasma membrane [UNKNOWN][IEA] integral to membrane [IEA] cytosol [UNKNOWN] plasma membrane [UNKNOWN]
Biological Process:	T cell costimulation [UNKNOWN][IMP] T cell activation [IMP] positive regulation of isotype switching to IgG isotypes [UNKNOWN][IEA] positive regulation of T cell proliferation [UNKNOWN][ISS] positive regulation of mitosis [UNKNOWN][ISS] induction of apoptosis by extracellular signals [UNKNOWN][IEA] positive regulation of inflammatory response to antigenic stimulus [UNKNOWN][IEA] positive regulation of interleukin-2 biosynthetic process [UNKNOWN][ISS] immune response [TAS] positive regulation of alpha-beta T cell proliferation [UNKNOWN][IEA] regulation of defense response to virus by virus [UNKNOWN] regulatory T cell differentiation [UNKNOWN] negative thymic T cell selection [UNKNOWN][IEA]
Molecular Function:	coreceptor activity [NAS] SH3/SH2 adaptor activity [UNKNOWN] protein binding [UNKNOWN] protein homodimerization activity [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTLRLLFLAL SFFSVQVTEN KILVKQSPLL VVDNNEVSLS CRYSYNLLAK EFRASLYKGV  60
   61 NSDVEVCVGN GNFTYQPQFR PNVGFNCDGN FDNETVTFRL WNLDVNHTDI YFCKIEVMYP 120
  121 PPYLDNEKSN GTIIHIKEKH LCHAQTSPKL FWPLVVVAGV LLCYGLLVTV TLCIIWTNSR 180
  181 RNRLLQSDYM NMTPRRLGPT RKHYQPYAPA RDFAAYRP

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: CD28_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: