YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: SMAD2_RAT

General Information:
Name(s) found: SMAD2_RAT [Swiss-Prot]
Description(s) found:
Found 27 descriptions.
SHOW ALL
  • Mothers against decapentaplegic homolog 2 OS=Rattus norvegicus GN=Smad2 PE=1 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 467 amino acids

    Gene Ontology:
    Cellular Component: nucleus [UNKNOWN][IDA][ISS]
    transcription factor complex [UNKNOWN][IEA][ISS]
    cytoplasm [UNKNOWN][IDA]
    cytosol [UNKNOWN]
    activin responsive factor complex [UNKNOWN][IEA]
    protein complex [IDA]
    intracellular [IEA]
    nucleoplasm [UNKNOWN]
    Biological Process: organ growth [UNKNOWN][IEA]
    insulin secretion [UNKNOWN][IEA]
    zygotic specification of dorsal/ventral axis [UNKNOWN][IEA]
    endoderm development [UNKNOWN][IEA]
    negative regulation of cell proliferation [IMP]
    post-embryonic development [UNKNOWN][IEA]
    palate development [IEA]
    transforming growth factor beta receptor signaling pathway [UNKNOWN][IEA][ISS]
    anterior/posterior pattern formation [UNKNOWN][ISS]
    positive regulation of transcription [UNKNOWN]
    protein amino acid phosphorylation [UNKNOWN][IEA]
    positive regulation of transcription from RNA polymerase II promoter [UNKNOWN][ISS]
    embryonic foregut morphogenesis [UNKNOWN][IEA]
    positive regulation of epithelial to mesenchymal transition [IEA]
    heart development [UNKNOWN]
    response to glucose stimulus [UNKNOWN][IEA]
    paraxial mesoderm morphogenesis [UNKNOWN][ISS]
    positive regulation of gene-specific transcription [IEA]
    negative regulation of transcription, DNA-dependent [UNKNOWN][IEA]
    in utero embryonic development [UNKNOWN][IEA]
    positive regulation of transcription, DNA-dependent [UNKNOWN][ISS]
    mesoderm formation [UNKNOWN][ISS]
    lung development [UNKNOWN][IEA]
    pancreas development [UNKNOWN][IEA]
    response to cholesterol [UNKNOWN][IEA]
    common-partner SMAD protein phosphorylation [UNKNOWN]
    SMAD protein complex assembly [UNKNOWN][IEA]
    embryonic pattern specification [UNKNOWN][IEA]
    regulation of transcription, DNA-dependent [IEA]
    pattern specification process [UNKNOWN]
    embryonic cranial skeleton morphogenesis [UNKNOWN][IEA]
    developmental growth [UNKNOWN][IEA]
    pericardium development [UNKNOWN][IEA]
    gastrulation [UNKNOWN][IEA]
    intracellular signaling pathway [UNKNOWN][ISS]
    ureteric bud development [UNKNOWN][IEA]
    cell fate commitment [UNKNOWN][ISS]
    regulation of binding [UNKNOWN][ISS]
    regulation of transforming growth factor beta receptor signaling pathway [UNKNOWN][IEA]
    Molecular Function: transforming growth factor beta receptor binding [UNKNOWN]
    double-stranded DNA binding [UNKNOWN][ISS]
    chromatin binding [UNKNOWN][IEA]
    transcription factor binding [UNKNOWN][IPI][ISS]
    DNA binding [UNKNOWN]
    transcription factor activity [UNKNOWN][IEA]
    protein binding [UNKNOWN][IEA][IPI]
    ubiquitin protein ligase binding [UNKNOWN][IEA]
    transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity [UNKNOWN][IEA]
    R-SMAD binding [UNKNOWN][IEA]
    co-SMAD binding [UNKNOWN][IEA]
    promoter binding [UNKNOWN][IEA]
    transcription activator activity [UNKNOWN][ISS]
    I-SMAD binding [UNKNOWN]
    type I transforming growth factor beta receptor binding [UNKNOWN][IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSILPFTPP VVKRLLGWKK SAGGSGGAGG GEQNGQEEKW CEKAVKSLVK KLKKTGRLDE  60
   61 LEKAITTQNC NTKCVTIPST CSEIWGLSTA NTVDQWDTTG LYSFSEQTRS LDGRLQVSHR 120
  121 KGLPHVIYCR LWRWPDLHSH HELKAIENCE YAFSLKKDEV CVNPYHYQRV ETPVLPPVLV 180
  181 PRHTEILTEL PPLDDYTHSI PENTNFPAGI EPQSNYIPET PPPGYISEDG ETSDQQLNQS 240
  241 MDTGSPAELS PTTLSPVNHS LDLQPVTYSE PAFWCSIAYY ELNQRVGETF HASQPSLTVD 300
  301 GFTDPSNSER FCLGLLSNVN RNATVEMTRR HIGRGVRLYY IGGEVFAECL SDSAIFVQSP 360
  361 NCNQRYGWHP ATVCKIPPGC NLKIFNNQEF AALLAQSVNQ GFEAVYQLTR MCTIRMSFVK 420
  421 GWGAEYRRQT VTSTPCWIEL HLNGPLQWLD KVLTQMGSPS VRCSSMS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle