General Information: |
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Name(s) found: |
SMAD2_RAT
[Swiss-Prot]
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Description(s) found:
SHOW ONLY BEST |
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Organism: | Rattus norvegicus |
Length: | 467 amino acids |
Gene Ontology: |
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Cellular Component: |
nucleus
[UNKNOWN][IDA][ISS]
transcription factor complex [UNKNOWN][IEA][ISS] cytoplasm [UNKNOWN][IDA] cytosol [UNKNOWN] activin responsive factor complex [UNKNOWN][IEA] protein complex [IDA] intracellular [IEA] nucleoplasm [UNKNOWN] |
Biological Process: |
organ growth
[UNKNOWN][IEA]
insulin secretion [UNKNOWN][IEA] zygotic specification of dorsal/ventral axis [UNKNOWN][IEA] endoderm development [UNKNOWN][IEA] negative regulation of cell proliferation [IMP] post-embryonic development [UNKNOWN][IEA] palate development [IEA] transforming growth factor beta receptor signaling pathway [UNKNOWN][IEA][ISS] anterior/posterior pattern formation [UNKNOWN][ISS] positive regulation of transcription [UNKNOWN] protein amino acid phosphorylation [UNKNOWN][IEA] positive regulation of transcription from RNA polymerase II promoter [UNKNOWN][ISS] embryonic foregut morphogenesis [UNKNOWN][IEA] positive regulation of epithelial to mesenchymal transition [IEA] heart development [UNKNOWN] response to glucose stimulus [UNKNOWN][IEA] paraxial mesoderm morphogenesis [UNKNOWN][ISS] positive regulation of gene-specific transcription [IEA] negative regulation of transcription, DNA-dependent [UNKNOWN][IEA] in utero embryonic development [UNKNOWN][IEA] positive regulation of transcription, DNA-dependent [UNKNOWN][ISS] mesoderm formation [UNKNOWN][ISS] lung development [UNKNOWN][IEA] pancreas development [UNKNOWN][IEA] response to cholesterol [UNKNOWN][IEA] common-partner SMAD protein phosphorylation [UNKNOWN] SMAD protein complex assembly [UNKNOWN][IEA] embryonic pattern specification [UNKNOWN][IEA] regulation of transcription, DNA-dependent [IEA] pattern specification process [UNKNOWN] embryonic cranial skeleton morphogenesis [UNKNOWN][IEA] developmental growth [UNKNOWN][IEA] pericardium development [UNKNOWN][IEA] gastrulation [UNKNOWN][IEA] intracellular signaling pathway [UNKNOWN][ISS] ureteric bud development [UNKNOWN][IEA] cell fate commitment [UNKNOWN][ISS] regulation of binding [UNKNOWN][ISS] regulation of transforming growth factor beta receptor signaling pathway [UNKNOWN][IEA] |
Molecular Function: |
transforming growth factor beta receptor binding
[UNKNOWN]
double-stranded DNA binding [UNKNOWN][ISS] chromatin binding [UNKNOWN][IEA] transcription factor binding [UNKNOWN][IPI][ISS] DNA binding [UNKNOWN] transcription factor activity [UNKNOWN][IEA] protein binding [UNKNOWN][IEA][IPI] ubiquitin protein ligase binding [UNKNOWN][IEA] transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity [UNKNOWN][IEA] R-SMAD binding [UNKNOWN][IEA] co-SMAD binding [UNKNOWN][IEA] promoter binding [UNKNOWN][IEA] transcription activator activity [UNKNOWN][ISS] I-SMAD binding [UNKNOWN] type I transforming growth factor beta receptor binding [UNKNOWN][IEA] |
Sequence: |
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Sequence: [PDR BLAST] [ProtParam] |
1 11 21 31 41 51 | | | | | | 1 MSSILPFTPP VVKRLLGWKK SAGGSGGAGG GEQNGQEEKW CEKAVKSLVK KLKKTGRLDE 60 61 LEKAITTQNC NTKCVTIPST CSEIWGLSTA NTVDQWDTTG LYSFSEQTRS LDGRLQVSHR 120 121 KGLPHVIYCR LWRWPDLHSH HELKAIENCE YAFSLKKDEV CVNPYHYQRV ETPVLPPVLV 180 181 PRHTEILTEL PPLDDYTHSI PENTNFPAGI EPQSNYIPET PPPGYISEDG ETSDQQLNQS 240 241 MDTGSPAELS PTTLSPVNHS LDLQPVTYSE PAFWCSIAYY ELNQRVGETF HASQPSLTVD 300 301 GFTDPSNSER FCLGLLSNVN RNATVEMTRR HIGRGVRLYY IGGEVFAECL SDSAIFVQSP 360 361 NCNQRYGWHP ATVCKIPPGC NLKIFNNQEF AALLAQSVNQ GFEAVYQLTR MCTIRMSFVK 420 421 GWGAEYRRQT VTSTPCWIEL HLNGPLQWLD KVLTQMGSPS VRCSSMS |
NOT SHOWING SINGLE HITS. [ Show Single Hits ]
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Protein predicted to be: | GLOBULAR (No transmembrane regions or signal peptide) |
Confidence of classification: | 0.98 |
Source: Reynolds et al. (2008)