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Protein Overview: NCBP1

General Information:
Name(s) found: NCBP1 [HGNC (HUGO)]
Description(s) found:
Found 44 descriptions.
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  • nuclear cap binding protein subunit 1, 80kDa [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 790 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRRRHSDEN DGGQPHKRRK TSDANETEDH LESLICKVGE KSACSLESNL EGLAGVLEAD  60
   61 LPNYKSKILR LLCTVARLLP EKLTIYTTLV GLLNARNYNF GGEFVEAMIR QLKESLKANN 120
  121 YNEAVYLVRF LSDLVNCHVI AAPSMVAMFE NFVSVTQEED VPQVRRDWYV YAFLSSLPWV 180
  181 GKELYEKKDA EMDRIFANTE SYLKRRQKTH VPMLQVWTAD KPHPQEEYLD CLWAQIQKLK 240
  241 KDRWQERHIL RPYLAFDSIL CEALQHNLPP FTPPPHTEDS VYPMPRVIFR MFDYTDDPEG 300
  301 PVMPGSHSVE RFVIEENLHC IIKSHWKERK TCAAQLVSYP GKNKIPLNYH IVEVIFAELF 360
  361 QLPAPPHIDV MYTTLLIELC KLQPGSLPQV LAQATEMLYM RLDTMNTTCV DRFINWFSHH 420
  421 LSNFQFRWSW EDWSDCLSQD PESPKPKFVR EVLEKCMRLS YHQRILDIVP PTFSALCPAN 480
  481 PTCIYKYGDE SSNSLPGHSV ALCLAVAFKS KATNDEIFSI LKDVPNPNQD DDDDEGFSFN 540
  541 PLKIEVFVQT LLHLAAKSFS HSFSALAKFH EVFKTLAESD EGKLHVLRVM FEVWRNHPQM 600
  601 IAVLVDKMIR TQIVDCAAVA NWIFSSELSR DFTRLFVWEI LHSTIRKMNK HVLKIQKELE 660
  661 EAKEKLARQH KRRSDDDDRS SDRKDGVLEE QIERLQEKVE SAQSEQKNLF LVIFQRFIMI 720
  721 LTEHLVRCET DGTSVLTPWY KNCIERLQQI FLQHHQIIQQ YMVTLENLLF TAELDPHILA 780
  781 VFQQFCALQA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run gi|14317902, gi|... No Comments Cheeseman, I.M., et al. (2004)
    View Run MIS12 No Comments Cheeseman, I.M., et al. (2004)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..790] PSI-BLAST 1000.0 CBP80, 80KDa nuclear cap-binding protein

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • RNA cap binding
    		•  6.31996430626206 bayes_pls_golite062009
  • RNA binding
    		•  4.20683443264388 bayes_pls_golite062009
  • binding
    		•  3.0667965351474 bayes_pls_golite062009
  • protein binding
    		•  2.78733902345842 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.74745843355294 bayes_pls_golite062009
  • mRNA binding
    		•  2.49094746544717 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.16673352512615 bayes_pls_golite062009
  • DNA binding
    		•  1.95242774903625 bayes_pls_golite062009
  • structural molecule activity
    		•  1.49689395735141 bayes_pls_golite062009
  • transcription activator activity
    		•  1.33885628961586 bayes_pls_golite062009
  • transcription factor activity
    		•  1.20660383756339 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.03835316513447 bayes_pls_golite062009
  • RNA 7-methylguanosine cap binding
    		•  0.841392474686331 bayes_pls_golite062009
  • hydrolase activity
    		•  0.42501390959416 bayes_pls_golite062009
  • actin binding
    		•  0.278432079866074 bayes_pls_golite062009
  • transcription factor binding
    		•  0.0221966060394205 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle