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Protein Overview: EFR3

General Information:
Name(s) found: EFR3 / YMR212C [SGD]
Description(s) found:
Found 26 descriptions.
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  • Non-essential protein of unknown function; exhibits synthetic lethal genetic interactions with PHO85; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies and is phosphorylated [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 782 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed articleLink to PubMed article]
    Biological Process: cell morphogenesis [IGILink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQLSMRMMFT PKHQKLVNQC YPTGRTTDKK PKSSETSYLL YYVNSRRSKL EKVSTYLIKR  60
   61 STSDLNHRRI GNIAVTLDLM NKIVLHCKEN LNVFVKDFLY IMNKVLSNNN FNNDVSVVEL 120
  121 IELAFSSICQ NLDDVLCNGD MEFVQLYQNF VDLFFKIVTE RIHNDDMLLK CCIDISNTNS 180
  181 VSSNPQLNHF VSKSVAYTIS KFQERNPKFK TLSLEAALES NLGKRLSRTQ TRTIGLDKAA 240
  241 EDNHDLSVKA LQSYFNTTET DKLNLSIRTL LRCLQSTPNK ELLEFVCNGI PVQLRYIVIL 300
  301 LLVRQLSDKD KNVNPIVSLK LMSSLLVSDV SIVGLSVLDI MRKLLNFQLK NATNKEVVAQ 360
  361 SCITMTDLNH KTYYAEQTSD MLYELLLKLK SDTVKDVEKN AVVEDIDFLV EHITQPSISL 420
  421 ELFIDLAHYM KNHIICLFNI VETEVPSSIL FSKLYSLLRE LDSHGVQKEM MEEIFDKYGK 480
  481 MALLSGLNYF LENVSEPEYT YYSYHLQAAN FLKLNDYKSQ TEYKMQTRTL FTKEDLLSYY 540
  541 SDTGSNKYSK KGAQILLSRD NQISTSDLLS DSQVRTTPLE YKNVPNAIFS NGKAVYDNND 600
  601 FAAKQNKFDN SIDDNIEEAN DTVISDANAK GSIYRFVAED ARSWKTMRAT APKVSDLKKT 660
  661 MNEKNIPNNM KRDGSFRGSQ SVKSRVTNIT FLLNELKTFS DDANKIKDPD EENIVGLDKI 720
  721 DVARSNSLRL APISSLSDRS SIGNRKSFLQ KTATGENQND DFKDANEDLH SLSSRGKIFS 780
  781 ST

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #03 Alpha Factor Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data EFR3 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..416] MSA 4.012968 View MSA. No confident structure predictions are available.
    2 View Details [417..782] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle