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View Structure Prediction Details

Protein: EFR3
Organism: Saccharomyces cerevisiae
Length: 782 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EFR3.

Description E-value Query
Range
Subject
Range
EFR3_YEAST - Protein EFR3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=EFR3 PE=1 SV=1
EFR3 - Non-essential protein of unknown function; exhibits synthetic lethal genetic interactions with PHO85...
0.0 [1..782] [1..782]
gi|2495710, gi|1... - gi|2495710|sp|Q14156|K0143_HUMAN Protein KIAA0143, gi|1469868|dbj|BAA09764.1| KIAA0143 [Homo sapiens...
0.0 [10..515] [77..590]
CE01843 - status:Partially_confirmed UniProt:Q09263 protein_id:AAC46791.1
0.0 [10..514] [11..518]
EFR3_SCHPO - Protein efr3 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=efr3 PE=1 SV=1
SPCC794.08 - HEAT repeat protein, unknown biological role
0.0 [5..415] [1..443]
gi|4218979 - gi|4218979|gb|AAD12254.1| putative transmembrane protein cmp44E [Drosophila melanogaster]
0.0 [10..487] [12..462]
gi|8810459, gi|2... - gi|8810459|gb|AAF80120.1|AC024174_2 Contains similarity to an unknown protein T11A7.7 gi|2335096 fro...
0.0 [12..419] [32..466]

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Predicted Domain #1
Region A:
Residues: [1-416]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQLSMRMMFT PKHQKLVNQC YPTGRTTDKK PKSSETSYLL YYVNSRRSKL EKVSTYLIKR  60
   61 STSDLNHRRI GNIAVTLDLM NKIVLHCKEN LNVFVKDFLY IMNKVLSNNN FNNDVSVVEL 120
  121 IELAFSSICQ NLDDVLCNGD MEFVQLYQNF VDLFFKIVTE RIHNDDMLLK CCIDISNTNS 180
  181 VSSNPQLNHF VSKSVAYTIS KFQERNPKFK TLSLEAALES NLGKRLSRTQ TRTIGLDKAA 240
  241 EDNHDLSVKA LQSYFNTTET DKLNLSIRTL LRCLQSTPNK ELLEFVCNGI PVQLRYIVIL 300
  301 LLVRQLSDKD KNVNPIVSLK LMSSLLVSDV SIVGLSVLDI MRKLLNFQLK NATNKEVVAQ 360
  361 SCITMTDLNH KTYYAEQTSD MLYELLLKLK SDTVKDVEKN AVVEDIDFLV EHITQP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [417-782]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SISLELFIDL AHYMKNHIIC LFNIVETEVP SSILFSKLYS LLRELDSHGV QKEMMEEIFD  60
   61 KYGKMALLSG LNYFLENVSE PEYTYYSYHL QAANFLKLND YKSQTEYKMQ TRTLFTKEDL 120
  121 LSYYSDTGSN KYSKKGAQIL LSRDNQISTS DLLSDSQVRT TPLEYKNVPN AIFSNGKAVY 180
  181 DNNDFAAKQN KFDNSIDDNI EEANDTVISD ANAKGSIYRF VAEDARSWKT MRATAPKVSD 240
  241 LKKTMNEKNI PNNMKRDGSF RGSQSVKSRV TNITFLLNEL KTFSDDANKI KDPDEENIVG 300
  301 LDKIDVARSN SLRLAPISSL SDRSSIGNRK SFLQKTATGE NQNDDFKDAN EDLHSLSSRG 360
  361 KIFSST

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle