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Protein Overview: UBP11

General Information:
Name(s) found: UBP11 / YKR098C [SGD]
Description(s) found:
Found 24 descriptions.
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  • Ubiquitin-specific protease that cleaves ubiquitin from ubiquitinated proteins [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 717 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: biological_process [ND]
    Molecular Function: ubiquitin-specific protease activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLNPDQILN LVRKVYEVDI KQFYSQLRLK NLRGLLDHAA HLFNVYLRDL EINQEMEALT  60
   61 AFIIGCYYLY LIIPQSLQFQ TRNNLYSSYA KLKNDYQDEH VMGYVLKVVR DESTVIVDRY 120
  121 LAESNGICRT IKRKRAYSLP LRPLPVHMAS LSIHNKFDGS LHEIPNELTK PTNDNSKEDI 180
  181 VRESNQIASS NKLEAGSEVA YYTSKEALSK PSYLKLSTGK DALFKTLSSP ATAPPVHSLE 240
  241 VSSQIRDSSQ DSSSSLSKVE KPKEEEGKIE AIESSAPKAY NLPVIEDSND LLSELSITGL 300
  301 QNPCNTCYIN SIIQCLFGTT LFRDLFLTKK YRLFLNTNKY PKEVQLSRSI YVLFKKMYLN 360
  361 GGRAIIPNRF LKMCKKLRPD LNIPDDQQDT QEFLLIVLAR IHEELSNENV VKYYPDLVSY 420
  421 DANALQVNPS KYEKWYERNV ITDGLSPIDH IYRGQLENIL KCQRCGNSSY SYSTFYVLSL 480
  481 AIPKLSLYSF TSKSRKIKLE DCINLFTGDE ELSGDNAWDC PNCRITDSKS KKEEITSQKK 540
  541 KSTIFGFHSR SRSKSPHHHH HHHHSSDDST KNAKKRNSKK LTTIKSLDFI VLPPILVIHL 600
  601 SRFYYDLTKK NSTVITYPLI LNIILKNGKV IRYKLYGTVN HSGNLINGHY TSVVNKEKSH 660
  661 EIGLNRQVWV TFDDDYIQQH RKDRNNFEAG KTEMSSDEVY VLFYERMDEE NYEEEFC

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) ASK10 ATG1 BMH2 KIC1 NTH1 PIK1 REG1 RFX1 SOG2 UBP11 YDR348C YNR014W

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #24 Asynchronous Prep3-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #26 Asynchronous Prep4-TiO2 Phosphopeptide enriched, Steps1-2 Keck JM, et al. (2011)
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #30 Asynchronous Prep6-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #11 Mitotic Prep1-TiO2 enriched, new search criteria Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..54] deduced N/A Confident ab initio structure predictions are available.
    2 View Details [55..246] MSA 1.14798 View MSA. No confident structure predictions are available.
    3 View Details [247..382] Pfam 13.327902 No description for PF00442 was found. No confident structure predictions are available.
    4 View Details [383..522] MSA 2.236988 View MSA. No confident structure predictions are available.
    5 View Details [523..622] deduced N/A No confident structure predictions are available.
    6 View Details [623..717] Pfam 23.070581 Ubiquitin carboxyl-terminal hydrolase No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.54

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle