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View Structure Prediction Details

Protein: UBP11
Organism: Saccharomyces cerevisiae
Length: 717 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UBP11.

Description E-value Query
Range
Subject
Range
UBP11_YEAST - Ubiquitin carboxyl-terminal hydrolase 11 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN...
UBP11 - Ubiquitin-specific protease that cleaves ubiquitin from ubiquitinated proteins
0.0 [1..717] [1..717]
gi|2655204 - gi|2655204|gb|AAC53587.1| ubiquitin-specific protease [Mus musculus]
5.0E-79 [92..491] [83..490]
gi|16552833, gi|... - gi|21361712|ref|NP_004196.3| ubiquitin specific peptidase 2 isoform a [Homo sapiens], gi|16552833|db...
9.0E-79 [121..705] [107..597]
gi|3800764 - gi|3800764|gb|AAC68865.1| ubiquitin specific protease 66 [Gallus gallus]
3.0E-78 [290..705] [38..376]
gi|6492126, gi|5... - gi|6492126|gb|AAF14190.1|AF106659_1 deubiquitinating enzyme Ubp69 [Rattus norvegicus], gi|51592088|r...
2.0E-76 [121..705] [107..610]

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Predicted Domain #1
Region A:
Residues: [1-54]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLNPDQILN LVRKVYEVDI KQFYSQLRLK NLRGLLDHAA HLFNVYLRDL EINQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.839 0.029 ubiquitin-specific protease activity a.144.1 PABC (PABP) domain

Predicted Domain #2
Region A:
Residues: [55-246]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EMEALTAFII GCYYLYLIIP QSLQFQTRNN LYSSYAKLKN DYQDEHVMGY VLKVVRDEST  60
   61 VIVDRYLAES NGICRTIKRK RAYSLPLRPL PVHMASLSIH NKFDGSLHEI PNELTKPTND 120
  121 NSKEDIVRES NQIASSNKLE AGSEVAYYTS KEALSKPSYL KLSTGKDALF KTLSSPATAP 180
  181 PVHSLEVSSQ IR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [247-382]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSSQDSSSSL SKVEKPKEEE GKIEAIESSA PKAYNLPVIE DSNDLLSELS ITGLQNPCNT  60
   61 CYINSIIQCL FGTTLFRDLF LTKKYRLFLN TNKYPKEVQL SRSIYVLFKK MYLNGGRAII 120
  121 PNRFLKMCKK LRPDLN

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 13.327902
Match: PF00442
Description: No description for PF00442 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [383-522]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IPDDQQDTQE FLLIVLARIH EELSNENVVK YYPDLVSYDA NALQVNPSKY EKWYERNVIT  60
   61 DGLSPIDHIY RGQLENILKC QRCGNSSYSY STFYVLSLAI PKLSLYSFTS KSRKIKLEDC 120
  121 INLFTGDEEL SGDNAWDCPN 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [523-622]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CRITDSKSKK EEITSQKKKS TIFGFHSRSR SKSPHHHHHH HHSSDDSTKN AKKRNSKKLT  60
   61 TIKSLDFIVL PPILVIHLSR FYYDLTKKNS TVITYPLILN 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [623-717]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IILKNGKVIR YKLYGTVNHS GNLINGHYTS VVNKEKSHEI GLNRQVWVTF DDDYIQQHRK  60
   61 DRNNFEAGKT EMSSDEVYVL FYERMDEENY EEEFC

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 23.070581
Match: PF00443
Description: Ubiquitin carboxyl-terminal hydrolase

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle