Protein Overview: YKR043C

General Information:
Name(s) found:	YKR043C [SGD]
Description(s) found: SHOW ONLY BEST	gi\|6322896\|ref\|NP_012969.1\| Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; Ykr043cp [Saccharomyces cerevisiae] [NCBI NR] gi\|549613\|sp\|P36136.1\|YK23_YEAST RecName: Full=Uncharacterized protein YKR043C [NCBI NR] pir\|\|S38115 hypothetical protein YKR043c - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|486491\|emb\|CAA82119.1\| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR] Uncharacterized protein YKR043C OS=Saccharomyces cerevisiae GN=YKR043C PE=1 SV=1 [Swiss-Prot] Putative phosphoglycerate mutase [mips] Metal-independent fructose 1,6-bisphosphatase, may play a role in gluconeogenesis under metal-limiting conditions; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus [SGD] YKR043C, Chr XI from 520534-521349, reverse complement [yeast_orfs2] Chr XI from 520534-521349, reverse complement [yeastorf3.fasta] Chr XI from 521349-520534, reverse complement [yeastorf5.fasta] (P36136) Hypothetical 31.0 kDa protein in GAP1-NAP1 intergenic region [4932.FASTACCERV.txt] YKR043C SGDID:S0001751, Chr XI from 521354-520539, reverse complement, Uncharacterized ORF [yeastflysequest.fasta] Ykr043cp [Saccharomyces cerevisiae]gi\|486491\|emb\|CAA82119.1\| unnamed protein product [Saccharomyces cerevisiae]gi\|539256\|pir\|\|S38115 hypothetical protein YKR043c - yeast (Saccharomyces cerevisiae)gi\|549613\|sp\|P36136\|YK23_YEAST HYPOTHETICAL 31.0 KD PROT [nrdb_11152004_Chlamydomonas] YKR043C SGDID:S000001751, Chr XI from 521354-520539, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; Ykr043cp [Saccharomyces cerevisiae] [nr-271106-contam.fasta] unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Uncharacterized protein YKR043C [nr-271106-contam.fasta] [chemostatdb.fasta] Sedoheptulose 1,7-bisphosphatase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SHB17 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] SHB17 SGDID:S000001751, Chr XI from 521712-520897, Genome Release 64-1-1, reverse complement, Verified ORF, "Sedoheptulose bisphosphatase involved in riboneogenesis; dephosphorylates sedoheptulose 1,7-bisphosphate, which is converted via the nonoxidative pentose phosphate pathway to ribose-5-phosphate; facilitates the conversion of glycolytic intermediates to pentose phosphate units; also has fructose 1,6-bisphosphatase activity but this is probably not biologically relevant, since deletion does not affect FBP levels; GFP-fusion protein localizes to the cytoplasm and nucleus" [yeast-030211-contam.fasta] SHB17 SGDID:S000001751, Chr XI from 521712-520897, Genome Release 64-2-1, reverse complement, Verified ORF, "Sedoheptulose bisphosphatase involved in riboneogenesis; dephosphorylates sedoheptulose 1,7-bisphosphate, which is converted via the nonoxidative pentose phosphate pathway to ribose-5-phosphate; facilitates the conversion of glycolytic intermediates to pentose phosphate units; also has fructose 1,6-bisphosphatase activity but this is probably not biologically relevant, since deletion does not affect FBP levels; GFP-fusion protein localizes to the cytoplasm and nucleus" [20141208_orf_trans.fasta] TR3075\|c0_g1_i1\|g.2192 ORF TR3075\|c0_g1_i1\|g.2192 TR3075\|c0_g1_i1\|m.2192 type:complete len:272 (+) TR3075\|c0_g1_i1:1367-2182(+) [Y12_S_cerevisiae-Sep2015-contam.fasta] TR975\|c0_g1_i1\|g.640 ORF TR975\|c0_g1_i1\|g.640 TR975\|c0_g1_i1\|m.640 type:complete len:272 (+) TR975\|c0_g1_i1:81-896(+) [DBVPG6044_S_cerevisiae-Sep2015-contam.fasta] YKR043C SGDID:S000001751, Chr XI from 521712-520897, Genome Release 64-1-1, reverse complement, Verified ORF, "Sedoheptulose bisphosphatase involved in riboneogenesis; dephosphorylates sedoheptulose 1,7-bisphosphate, which is converted via the nonoxidative pentose phosphate pathway to ribose-5-phosphate; facilitates the conversion of glycolytic intermediates to pentose phosphate units; also has fructose 1,6-bisphosphatase activity but this is probably not biologically relevant, since deletion does not affect FBP levels; GFP-fusion protein localizes to the cytoplasm and nucleus" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta] asmbl_6386\|g.5027 ORF asmbl_6386\|g.5027 asmbl_6386\|m.5027 type:complete len:272 (+) asmbl_6386:2333-3148(+) [Y12_Trinity_v2_2_0_PASA_6May2016-contam.fasta] ID=asmbl_6630\|g.4259 ORF ID=asmbl_6630\|g.4259 ID=asmbl_6630\|m.4259 type:complete len:272 (+) ID=asmbl_6630:116-931(+) [DBVPG6044_quiverGenomes_Trinity_v2_2_0_PASA_2June2016-contam.fasta] ID=asmbl_6407\|g.3969 ORF ID=asmbl_6407\|g.3969 ID=asmbl_6407\|m.3969 type:complete len:272 (+) ID=asmbl_6407:2333-3148(+) [Y12_quiver_Trinity_v2_2_0_PASA_2June2016-contam.fasta]
Organism:	Saccharomyces cerevisiae
Length:	271 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] cytoplasm [IDA]
Biological Process:	biological_process [ND]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSLTPRCII VRHGQTEWSK SGQYTGLTDL PLTPYGEGQM LRTGESVFRN NQFLNPDNIT  60
   61 YIFTSPRLRA RQTVDLVLKP LSDEQRAKIR VVVDDDLREW EYGDYEGMLT REIIELRKSR 120
  121 GLDKERPWNI WRDGCENGET TQQIGLRLSR AIARIQNLHR KHQSEGRASD IMVFAHGHAL 180
  181 RYFAAIWFGL GVQKKCETIE EIQNVKSYDD DTVPYVKLES YRHLVDNPCF LLDAGGIGVL 240
  241 SYAHHNIDEP ALELAGPFVS PPEEESQHGD V

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Krogan NJ, et al. (2006)		IPP1 ROM2 YKR043C

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	CDC4	YKR043C	1	Unpublished Fields Lab Data
View Screen	SAM35	YKR043C	1	Unpublished Fields Lab Data

Microscopy / Localization Data

New Feature: Upload Your Own Microscopy Data

	PROTEIN(S)	PUBLICATION
View Data	YKR043C	Huh WK, et al. (2003)

Protein Structure Data

[What does the above image mean?]
[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..271]	PSI-BLAST	117.39794	Phosphoglycerate mutase

Functions predicted (by domain):

Gene Ontology predictions

Term	Confidence	Notes
catalytic activity	0.610716769500575	bayes_pls_golite062009
binding	0.125625514513293	bayes_pls_golite062009

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.96

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2