YRC Public Data Repository - Protein Structure Prediction

Protein:	YKR043C
Organism:	Saccharomyces cerevisiae
Length:	271 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YKR043C.

Description	E-value	Query Range	Subject Range
SHB17_YEAST - Sedoheptulose 1,7-bisphosphatase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SHB17 P... gi\|151941584 - gi\|151941584\|gb\|EDN59947.1\| conserved protein [Saccharomyces cerevisiae YJM789] YKR043C - Metal-independent fructose 1,6-bisphosphatase, may play a role in gluconeogenesis under metal-limiti...	5.0E-65	[1..271]	[1..271]
gi\|149291242, gi... - gi\|149366868\|ref\|ZP_01888902.1\| phosphoglycerate mutase 1 [Yersinia pestis CA88-4125], gi\|149291242\|... GPMA_YERPP - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Yersinia pestis (strain Pestoides F) GN... GPMA_YERPG - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Yersinia pestis bv. Antiqua (strain Ang... gi\|165923463, gi... - gi\|165924403\|ref\|ZP_02220235.1\| 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [Yersinia ... gi\|165938334, gi... - gi\|165938334\|ref\|ZP_02226892.1\| 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [Yersinia ... GPMA_YERPS - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Yersinia pseudotuberculosis serotype I ... GPMA_YERPE - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Yersinia pestis GN=gpmA PE=3 SV=3 gi\|15979199, gi\|... - gi\|218928300\|ref\|YP_002346175.1\| phosphoglycerate mutase 1 [Yersinia pestis CO92], gi\|16121432\|ref\|N... GPMA_YERPS - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Yersinia pseudotuberculosis GN=gpmA PE=... GPMA_YERP3 - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Yersinia pseudotuberculosis serotype O:... GPMA_YERPA - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Yersinia pestis bv. Antiqua (strain Ant... GPMA_YERPN - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Yersinia pestis bv. Antiqua (strain Nep... gi\|166011548, gi... - gi\|166011548\|ref\|ZP_02232446.1\| 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [Yersinia ... gi\|166211470, gi... - gi\|166211470\|ref\|ZP_02237505.1\| 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [Yersinia ... gi\|167050137, gi... - gi\|167400188\|ref\|ZP_02305701.1\| 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [Yersinia ... gi\|229703894, gi... - gi\|229894009\|ref\|ZP_04509195.1\| phosphoglyceromutase 1 [Yersinia pestis Pestoides A], gi\|229703894\|g... gi\|167419786, gi... - gi\|167419786\|ref\|ZP_02311539.1\| 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [Yersinia ... gi\|229689522, gi... - gi\|229843175\|ref\|ZP_04463321.1\| phosphoglyceromutase 1 [Yersinia pestis biovar Orientalis str. India... gi\|167057206, gi... - gi\|167424357\|ref\|ZP_02316110.1\| 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [Yersinia ... gi\|229697437, gi... - gi\|229841071\|ref\|ZP_04461230.1\| phosphoglyceromutase 1 [Yersinia pestis biovar Orientalis str. PEXU2... GPMA_YERPY - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Yersinia pseudotuberculosis serotype O:... GPMA_YERPB - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Yersinia pseudotuberculosis serotype IB...	2.0E-49	[6..237]	[4..236]
gi\|214001890 - gi\|214001890\|ref\|ZP_03412625.1\| 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [Salmonell... GPMA_SALPC - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Salmonella paratyphi C (strain RKS4594)... gi\|213427699 - gi\|213427699\|ref\|ZP_03360449.1\| 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [Salmonell... GPMA_SALCH - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Salmonella choleraesuis GN=gpmA PE=3 SV... gi\|213582686 - gi\|213582686\|ref\|ZP_03364512.1\| 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [Salmonell... gi\|213649737 - gi\|213649737\|ref\|ZP_03379790.1\| 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [Salmonell... gi\|213854586 - gi\|213854586\|ref\|ZP_03382826.1\| 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [Salmonell... gi\|199602212, gi... - gi\|200389767\|ref\|ZP_03216378.1\| 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [Salmonell... GPMA_SALTI - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Salmonella typhi GN=gpmA PE=3 SV=3 gi\|204320976, gi... - gi\|204929982\|ref\|ZP_03221003.1\| 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [Salmonell... gi\|213163241 - gi\|213163241\|ref\|ZP_03348951.1\| 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [Salmonell... gi\|213420657 - gi\|213420657\|ref\|ZP_03353723.1\| 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [Salmonell... gi\|16759697 - gi\|16759697\|ref\|NP_455314.1\| phosphoglyceromutase [Salmonella enterica subsp. enterica serovar Typhi... GPMA_SALNS - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Salmonella newport (strain SL254) GN=gp... gi\|194456919, gi... - gi\|194470555\|ref\|ZP_03076539.1\| 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [Salmonell... GPMA_SALTI - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Salmonella typhi GN=gpmA PE=3 SV=3 GPMA_SALSV - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Salmonella schwarzengrund (strain CVM19... gi\|29138161, gi\|... - gi\|29142530\|ref\|NP_805872.1\| phosphoglyceromutase [Salmonella enterica subsp. enterica serovar Typhi... gi\|197264300, gi... - gi\|197264300\|ref\|ZP_03164374.1\| 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [Salmonell... GPMA_SALCH - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Salmonella choleraesuis GN=gpmA PE=3 SV... gi\|205334784, gi... - gi\|205334784\|gb\|EDZ21548.1\| 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [Salmonella en... gi\|168236694, gi... - gi\|197290171\|gb\|EDY29528.1\| 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [Salmonella en... GPMA_SALCH - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Salmonella choleraesuis (strain SC-B67)...	2.0E-49	[6..237]	[4..236]
gi\|7437400 - gi\|7437400\|pir\|\|A70182 phosphoglycerate mutase (gpmA) homolog - Lyme disease spirochete gi\|2688589, gi\|1... - gi\|2688589\|gb\|AAC67007.1\| phosphoglycerate mutase (gpmA) [Borrelia burgdorferi B31], gi\|15595003\|ref...	3.0E-49	[3..238]	[4..240]
GPMA_SALA4 - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Salmonella agona (strain SL483) GN=gpmA... GPMA_SALPB - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Salmonella paratyphi B (strain ATCC BAA... GPMA_SALHS - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Salmonella heidelberg (strain SL476) GN... GPMA_SALEP - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Salmonella enteritidis PT4 (strain P125... GPMA_SALG2 - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Salmonella gallinarum (strain 287/91 / ... gi\|167994417, gi... - gi\|205327722\|gb\|EDZ14486.1\| 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [Salmonella en... gi\|205324579, gi... - gi\|205324579\|gb\|EDZ12418.1\| 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [Salmonella en... GPMA_SALTY - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Salmonella typhimurium GN=gpmA PE=3 SV=... gi\|168263737, gi... - gi\|205347720\|gb\|EDZ34351.1\| 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [Salmonella en... gi\|205340128, gi... - gi\|205340128\|gb\|EDZ26892.1\| 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [Salmonella en... lcl\|NC_016856.1_... - [gene=gpmA] [protein=phosphoglyceromutase] [protein_id=YP_005236490.1] [location=complement(836703..... GPMA_SALTY - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Salmonella typhimurium (strain LT2 / SG... GPMA_SALTY - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Salmonella typhimurium GN=gpmA PE=3 SV=... GPMA_SALPB - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Salmonella paratyphi B (strain ATCC BAA...	5.0E-49	[6..237]	[4..236]
GPMA_ECO57 - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Escherichia coli O157:H7 GN=gpmA PE=3 S... gi\|254591305, gi... - gi\|254791905\|ref\|YP_003076742.1\| phosphoglyceromutase 1 [Escherichia coli O157:H7 str. TW14359], gi\|... gi\|30040333, gi\|... - gi\|30062089\|ref\|NP_836260.1\| phosphoglyceromutase [Shigella flexneri 2a str. 2457T], gi\|30040333\|gb\|... gi\|253972719, gi... - gi\|254160818\|ref\|YP_003043926.1\| phosphoglyceromutase [Escherichia coli B str. REL606], gi\|253972719... GPMA_ECOL6 - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Escherichia coli O6:H1 (strain CFT073 /... gi\|12513684, gi\|... - gi\|15800464\|ref\|NP_286476.1\| phosphoglyceromutase [Escherichia coli O157:H7 EDL933], gi\|12513684\|gb\|... gi\|253774281, gi... - gi\|254287606\|ref\|YP_003053354.1\| phosphoglyceromutase [Escherichia coli BL21(DE3)], gi\|253976913\|gb\|... EG11699 - phosphoglyceromutase 1 / Phosphoglycerate mutase, 2,3-bisphosphoglycerate-dependent; dPGM; Fur regul... gi\|251784237, gi... - gi\|251784237\|ref\|YP_002998541.1\| hypothetical protein B21_00697 [Escherichia coli BL21], gi\|24237651... GPMA_ECOBW - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Escherichia coli (strain K12 / MC4100 /... gi\|227839037, gi... - gi\|227884285\|ref\|ZP_04002090.1\| phosphoglyceromutase [Escherichia coli 83972], gi\|227839037\|gb\|EEJ49... GPMA_ECOL6 - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Escherichia coli O6 GN=gpmA PE=3 SV=2 GPMA_ECOLI - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (EC 5.4.2.1) (Phosphoglyceromutase) (PGAM)... GPMA_SHIFL - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Shigella flexneri GN=gpmA PE=3 SV=2 GPMA_SHIBS - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Shigella boydii serotype 4 (strain Sb22... gi\|56383240, gi\|... - gi\|56479689\|ref\|NP_706486.2\| phosphoglyceromutase [Shigella flexneri 2a str. 301], gi\|56383240\|gb\|AA... gi\|188487599, gi... - gi\|75511357\|ref\|ZP_00734042.1\| COG0588: Phosphoglycerate mutase 1 [Escherichia coli 53638], gi\|18849... GPMA_SHISS - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Shigella sonnei (strain Ss046) GN=gpmA ... GPMA_ECOLC - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Escherichia coli (strain ATCC 8739 / DS... GPMA_SHIB3 - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Shigella boydii serotype 18 (strain CDC... GPMA_ECOHS - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Escherichia coli O9:H4 (strain HS) GN=g... gi\|83584860, gi\|... - gi\|83584860\|ref\|ZP_00923519.1\| COG0588: Phosphoglycerate mutase 1 [Escherichia coli 101-1], gi\|19443... gi\|75237091, gi\|... - gi\|75237091\|ref\|ZP_00721145.1\| COG0588: Phosphoglycerate mutase 1 [Escherichia coli F11], gi\|1911741... gi\|192926788, gi... - gi\|75256339\|ref\|ZP_00728009.1\| COG0588: Phosphoglycerate mutase 1 [Escherichia coli E22], gi\|1930656... gi\|75228378, gi\|... - gi\|75228378\|ref\|ZP_00715026.1\| COG0588: Phosphoglycerate mutase 1 [Escherichia coli B7A], gi\|1911684... gi\|192957134, gi... - gi\|75235772\|ref\|ZP_00719927.1\| COG0588: Phosphoglycerate mutase 1 [Escherichia coli E110019], gi\|193... gi\|89107606, gi\|... - gi\|89107606\|ref\|AP_001386.1\| phosphoglyceromutase 1 [Escherichia coli str. K-12 substr. W3110], gi\|4... gi\|13360242, gi\|... - gi\|15830037\|ref\|NP_308810.1\| phosphoglyceromutase [Escherichia coli O157:H7 str. Sakai], gi\|13360242... GPMA_ECOL5 - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Escherichia coli O6:K15:H31 (strain 536... GPMA_SHIF8 - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Shigella flexneri serotype 5b (strain 8... gi\|168763345, gi... - gi\|189366417\|gb\|EDU84833.1\| 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [Escherichia c... gi\|189363482, gi... - gi\|189363482\|gb\|EDU81901.1\| 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [Escherichia c... gi\|168776500, gi... - gi\|187768149\|gb\|EDU31993.1\| 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [Escherichia c... gi\|189002856, gi... - gi\|189002856\|gb\|EDU71842.1\| 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [Escherichia c... gi\|189373126, gi... - gi\|189373126\|gb\|EDU91542.1\| 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [Escherichia c... gi\|168800813, gi... - gi\|189376939\|gb\|EDU95355.1\| 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [Escherichia c... GPMA_ECODH - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Escherichia coli (strain K12 / DH10B) G... GPMA_ECOSM - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Escherichia coli (strain SMS-3-5 / SECE... gi\|168750247, gi... - gi\|188015491\|gb\|EDU53613.1\| 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [Escherichia c... gi\|189355841, gi... - gi\|189355841\|gb\|EDU74260.1\| 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [Escherichia c... GPMA_ESCF3 - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Escherichia fergusonii (strain ATCC 354... GPMA_ECO8A - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Escherichia coli O8 (strain IAI1) GN=gp... GPMA_ECO45 - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Escherichia coli O45:K1 (strain S88 / E... GPMA_ECO81 - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Escherichia coli O81 (strain ED1a) GN=g... GPMA_ECO55 - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Escherichia coli (strain 55989 / EAEC) ... GPMA_ECO7I - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Escherichia coli O7:K1 (strain IAI39 / ... GPMA_ECOLU - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Escherichia coli O17:K52:H18 (strain UM... gi\|170769020, gi... - gi\|170769020\|ref\|ZP_02903473.1\| 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [Escherich... EG11699 - phosphoglyceromutase 1 / Phosphoglycerate mutase, 2,3-bisphosphoglycerate-dependent; dPGM; Fur regul... gi\|195936743 - gi\|195936743\|ref\|ZP_03082125.1\| phosphoglyceromutase 1 [Escherichia coli O157:H7 str. EC4024] gi\|208732453, gi... - gi\|208815805\|ref\|ZP_03256984.1\| 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [Escherich... GPMA_ECOK1 - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Escherichia coli O1:K1 / APEC GN=gpmA P... gi\|208822250, gi... - gi\|208822250\|ref\|ZP_03262569.1\| 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [Escherich... gi\|124531872, gi... - gi\|124531872\|ref\|ZP_01701971.1\| phosphoglycerate mutase 1 family [Escherichia coli B], gi\|124498293\|... GPMA_ECO5E - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Escherichia coli O157:H7 (strain EC4115... sp\|B7ULM8\|GPMA_ECO27 - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Escherichia coli O127:H6 (strain E2348/... GPMA_ECOSE - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Escherichia coli (strain SE11) GN=gpmA ... GPMA_ECO27 - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Escherichia coli O127:H6 (strain E2348/... gi\|217325929, gi... - gi\|217325929\|ref\|ZP_03442013.1\| 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [Escherich...	8.0E-49	[6..237]	[4..236]
GPMA_ECOLI - (P62707) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (EC 5.4.2.1) (Phosphoglyceromutas... GPMA_ECOL6 - (P62708) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (EC 5.4.2.1) (Phosphoglyceromutas... GPMA_ECO57 - (P62709) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (EC 5.4.2.1) (Phosphoglyceromutas... GPMA_SHIFL - (P62710) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (EC 5.4.2.1) (Phosphoglyceromutas...	9.0E-49	[6..237]	[3..235]
gi\|17427362 - gi\|17427362\|emb\|CAD13881.1\| probable 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (phos... gi\|17545072 - gi\|17545072\|ref\|NP_518474.1\| phosphoglyceromutase [Ralstonia solanacearum GMI1000]	3.0E-48	[3..235]	[18..251]
gi\|166159344, gi... - gi\|16904828\|gb\|AAL30898.1\| phosphoglycerate mutase [Schistosoma japonicum], gi\|166159344\|gb\|ABY83139...	3.0E-47	[5..240]	[3..239]

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Predicted Domain #1

Region A:
Residues: [1-271]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSLTPRCII VRHGQTEWSK SGQYTGLTDL PLTPYGEGQM LRTGESVFRN NQFLNPDNIT  60
   61 YIFTSPRLRA RQTVDLVLKP LSDEQRAKIR VVVDDDLREW EYGDYEGMLT REIIELRKSR 120
  121 GLDKERPWNI WRDGCENGET TQQIGLRLSR AIARIQNLHR KHQSEGRASD IMVFAHGHAL 180
  181 RYFAAIWFGL GVQKKCETIE EIQNVKSYDD DTVPYVKLES YRHLVDNPCF LLDAGGIGVL 240
  241 SYAHHNIDEP ALELAGPFVS PPEEESQHGD V

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	117.39794
Match:	1bq3D_
Description:	Phosphoglycerate mutase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.610716769500575	bayes_pls_golite062009
binding	0.125625514513293	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: