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Protein Overview: BNA3

General Information:
Name(s) found: BNA3 / YJL060W [SGD]
Description(s) found:
Found 24 descriptions.
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  • Kynurenine aminotransferase, catalyzes formation of kynurenic acid from kynurenine; potential Cdc28p substrate [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 444 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    mitochondrion [IDALink to PubMed articleLink to PubMed article]
    Biological Process: NAD biosynthetic process [IMPLink to PubMed article]
    Molecular Function: arylformamidase activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKQRFIRQFT NLMSTSRPKV VANKYFTSNT AKDVWSLTNE AAAKAANNSK NQGRELINLG  60
   61 QGFFSYSPPQ FAIKEAQKAL DIPMVNQYSP TRGRPSLINS LIKLYSPIYN TELKAENVTV 120
  121 TTGANEGILS CLMGLLNAGD EVIVFEPFFD QYIPNIELCG GKVVYVPINP PKELDQRNTR 180
  181 GEEWTIDFEQ FEKAITSKTK AVIINTPHNP IGKVFTREEL TTLGNICVKH NVVIISDEVY 240
  241 EHLYFTDSFT RIATLSPEIG QLTLTVGSAG KSFAATGWRI GWVLSLNAEL LSYAAKAHTR 300
  301 ICFASPSPLQ EACANSINDA LKIGYFEKMR QEYINKFKIF TSIFDELGLP YTAPEGTYFV 360
  361 LVDFSKVKIP EDYPYPEEIL NKGKDFRISH WLINELGVVA IPPTEFYIKE HEKAAENLLR 420
  421 FAVCKDDAYL ENAVERLKLL KDYL

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Gavin AC, et al. (2002) BNA3 CDC3

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #31 Asynchronous Prep (Protease cleavage) Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data BNA3 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..36]
    [63..335]    		 PSI-BLAST 482.9897 Aromatic aminoacid aminotransferase, AroAT
    2 View Details [37..62]
    [336..444]    		 PSI-BLAST 482.9897 Aromatic aminoacid aminotransferase, AroAT

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • L-aspartate:2-oxoglutarate aminotransferase activity
    		•  5.51961002550688 bayes_pls_golite062009
  • catalytic activity
    		•  2.29878871754893 bayes_pls_golite062009
  • glycine dehydrogenase (decarboxylating) activity
    		•  1.63055151623667 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor
    		•  1.63055151623667 bayes_pls_golite062009
  • transferase activity
    		•  1.44093490824786 bayes_pls_golite062009
  • transferase activity, transferring nitrogenous groups
    		•  1.28316822767388 bayes_pls_golite062009
  • transaminase activity
    		•  1.24990480711889 bayes_pls_golite062009
  • 4-aminobutyrate transaminase activity
    		•  0.99097016439114 bayes_pls_golite062009
  • 5-aminolevulinate synthase activity
    		•  0.54326874956263 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  0.319452731970428 bayes_pls_golite062009
  • pyridoxal phosphate binding
    		•  0.16957228630576 bayes_pls_golite062009
  • vitamin B6 binding
    		•  0.16957228630576 bayes_pls_golite062009
  • aromatic-amino-acid:2-oxoglutarate aminotransferase activity
    		•  0.0916183433120769 bayes_pls_golite062009
  • cystathionine beta-lyase activity
    		•  0.0833010353195099 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.013097682076602 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle