Protein Overview: POP6

General Information:
Name(s) found:	POP6 / YGR030C [SGD]
Description(s) found: Found 26 descriptions. SHOW ALL	Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends [SGD]
Organism:	Saccharomyces cerevisiae
Length:	158 amino acids
Gene Ontology:
Cellular Component:	ribonuclease MRP complex [IDA] nucleolar ribonuclease P complex [IDA]
Biological Process:	tRNA processing [TAS] rRNA processing [TAS] mRNA cleavage [IPI]
Molecular Function:	ribonuclease P activity [IMP] ribonuclease MRP activity [IMP]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MINGVYYNEI SRDLDISSST QCLRFLKETV IPSLANNGNN STSIQYHGIS KNDNIKKSVN  60
   61 KLDKQINMAD RSLGLQQVVC IFSYGPHIQK MLSILEIFKK GYIKNNKKIY QWNKLTSFDI 120
  121 KREGRNELQE ERLKVPILVT LVSDSEIIDL NLHSFTKQ

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Riffle et al. (2010) (Unpublished Data)		POP5 POP6 POP8 RPP1
View Details	Hazbun TR, et al. (2003)		POP1 POP3 POP4 POP5 POP6 POP8 RMP1 RPP1 SNM1
View Details	(MIPS) Mewes HW, et al. (2004)		POP1 POP3 POP4 POP5 POP6 POP7 POP8 RPP1 RPR2
View Details	Krogan NJ, et al. (2006)		POP1 POP3 POP4 POP5 POP6 POP7 RMP1 RPP1 RPR2 SNM1
View Details	Gavin AC, et al. (2002)		POP1 POP3 POP4 POP5 POP6 POP8 RPP1
View Details	Qiu et al. (2008)		POP1 POP3 POP4 POP5 POP6 POP7 POP8 RMP1 RPP1 RPR2 SNM1

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	RMP1	No Comments	Hazbun TR, et al. (2003)
View Run	CEP3	sample cbf3 from feb 2005	Sandall S, et all (2006)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	NPA3	POP6	2	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	POP6	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..158]	deduced	N/A	No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2