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Protein Overview: SOK1

General Information:
Name(s) found: SOK1 / YDR006C [SGD]
Description(s) found:
Found 25 descriptions.
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  • Protein whose overexpression suppresses the growth defect of mutants lacking protein kinase A activity; involved in cAMP-mediated signaling; localized to the nucleus; similar to the mouse testis-specific protein PBS13 [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 901 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    Biological Process: cAMP-mediated signaling [IGILink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDQPRTHSGP TTASNPAPSS TNSSSAPSAT NSKQERSSSS LSKPSSVVPS KDSPDGDAIA  60
   61 KTQAAALKND MKSGDTSTLD GSSQNIIPNR ASMQKYIDQS SDLLSRSSGV ITPSMSLNAS 120
  121 TNATNNDSSG NSANSSDLKI PIDRDNTIFK TFDTKTGQFL KNDDNEEEIR RNNKVDSIPP 180
  181 KNIYTNINNP SPSPPPSSKQ PPSASAPQLP PATEPHKEQA AQQQPPGNAS NFLRIFSNKK 240
  241 MRSHSVPTIL HSSLRKLSSH NQYYRNQNIL LNHPTPSGIS KKKFSRNHHQ PYLHSNNPLS 300
  301 SNPLSLKRAI FLNQQISGNA STNANNDNIN NSTATSMTNQ SFLSSSNFDL TLEDRINYIK 360
  361 ATPTPVPFPP INLQGLKEID LQEILKNPQL RHDIIFDPLL QFRPNLDGER GNKKRQLANI 420
  421 YWNDVQNEIY VYSKRPEIFQ YNRSRLVPLF DTLRDVLLTI VPQKESPMIN NVLDTELNIQ 480
  481 ELLKGSLIMS NLSGWLADLF KHHCAPMRDP WVDKMSNKFK EAERDSSLTR LIEGLRLVFQ 540
  541 ILETMKLDIA NHQIRILRPA LLSNAVEFEK QYFNTLIASK RVNLNTSLLW FDKKFNENVT 600
  601 AGLVRNPSSI TIPDVYNICI RSIINLLSCR KMVREYPTPL SFDHARLILL RADIRQIVCI 660
  661 LVCRLLFQQL VANDPSMDKA TKEYVIHTYS TKRLKNEIIS IITDEHGNCR WTKNTMSIAV 720
  721 HLCKVIDDLH REYDNNGSCE QARRPQLPSL DNSKITFAKS WLSKQTQPLS EVYGVLENRV 780
  781 FKSLEDAIFN RSECTIDGRV KQDFVYLYNT NNGNVGSTNT LSTTTDTASV KISPSLMSPS 840
  841 KTSTTTPTGN AIASRGLFAA TELEEFENVY RHLYALINLH WSVFGPHYIE MLGDKVNKKG 900
  901 I

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) HFM1 LYS4 NEW1 RBG1 SGD1 SOK1 SSZ1 TCB1 TGL5 TMA46 YEF3 YLR072W ZUO1
    View Details Ho Y, et al. (2002) ADR1 BMH1 BNR1 BOI2 CSR2 CYK3 GSY2 KCS1 NTH1 REG1 SOK1 STU1 SVL3 YFR017C YIL028W

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data SOK1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..347] deduced N/A No confident structure predictions are available.
    2 View Details [348..716] ab initio 9.18 No description for 1ldjA was found.
    3 View Details [717..812] ab initio 9.18 No description for 1ldjA was found.
    4 View Details [813..901] deduced N/A Confident ab initio structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle