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Protein Overview: UGA4

General Information:
Name(s) found: UGA4 / YDL210W [SGD]
Description(s) found:
Found 28 descriptions.
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  • Permease that serves as a gamma-aminobutyrate (GABA) transport protein involved in the utilization of GABA as a nitrogen source; catalyzes the transport of putrescine and delta-aminolevulinic acid (ALA); localized to the vacuolar membrane [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 571 amino acids

    Gene Ontology:
    Cellular Component: fungal-type vacuole membrane [IDALink to PubMed article]
    Biological Process: putrescine transport [IDALink to PubMed article]
    transport [TASLink to PubMed article]
    Molecular Function: putrescine transmembrane transporter activity [IDALink to PubMed article]
    gamma-aminobutyric acid:hydrogen symporter activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSMSSKNENK ISVEQRISTD IGQAYQLQGL GSNLRSIRSK TGAGEVNYID AAKSVNDNQL  60
   61 LAEIGYKQEL KRQFSTLQVF GIAFSIMGLL PSIASVMGGG LGGGPATLVW GWFVAAFFIL 120
  121 LVGITMAEHA SSIPTAGGLY YWTYYYAPEG YKEIISFIIG CSNSLALAAG VCSIDYGLAE 180
  181 EIAAAVTLTK DGNFEVTSGK LYGIFAGAVV VMCICTCVAS GAIARLQTLS IFANLFIIVL 240
  241 LFIALPIGTK HRMGGFNDGD FIFGKYENLS DWNNGWQFCL AGFMPAVWTI GSFDSCVHQS 300
  301 EEAKDAKKSV PIGIISSIAV CWILGWLIII CLMACINPDI DSVLDSKYGF ALAQIIYDSL 360
  361 GKKWAIAFMS LIAFCQFLMG ASITTAVSRQ VWAFSRDNGL PLSKYIKRVD SKYSVPFFAI 420
  421 LAACVGSLIL GLLCLIDDAA TDALFSLAVA GNNLAWSTPT VFRLTSGRDL FRPGPFYLGK 480
  481 IWSPIVAWTG VAFQLFIIIL VMFPSQQHGI TKSTMNYACV IGPGIWILAG IYYKVYKKKY 540
  541 YHGPATNLSD DDYTEAVGAD VIDTIMSKQE P

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) AVT4 GAP1 TPO3 UGA4 VBA1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen ELM1 UGA4 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..571] Pfam 5.853872 Amino acid permease No confident structure predictions are available.
    2 View Details [67..571] FFAS03 1.4 Crystal structure of LEUTAA, a bacterial homolog of Na+/Cl--dependent neurotransmitter transporters


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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