YRC Public Data Repository - Protein Structure Prediction

Protein:	UGA4
Organism:	Saccharomyces cerevisiae
Length:	571 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UGA4.

Description	E-value	Query Range	Subject Range
YI26_SCHPO - Uncharacterized amino-acid permease P7G5.06 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) G... SPAP7G5.06 - amino acid permease, unknown 4	4.0E-95	[3..569]	[1..567]
gi\|68470470, gi\|... - gi\|68470731\|ref\|XP_720611.1\| N-acetylglucosamine-inducible general amino acid permease [Candida albi... gi\|18568390 - gi\|18568390\|gb\|AAL76065.1\| Gap1 protein [Candida albicans] gi\|238882678 - gi\|238882678\|gb\|EEQ46316.1\| general amino-acid permease GAP1 [Candida albicans WO-1]	5.0E-92	[6..568]	[4..560]
LYP1_YEAST - Lysine-specific permease OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=LYP1 PE=1 SV=2 LYP1 - Lysine permease; one of three amino acid permeases (Alp1p, Can1p, Lyp1p) responsible for uptake of c... gi\|190409237 - gi\|190409237\|gb\|EDV12502.1\| lysine permease [Saccharomyces cerevisiae RM11-1a]	3.0E-91	[5..571]	[43..599]
gi\|447739 - gi\|447739\|prf\|\|1915304A nylB upstream ORF	3.0E-89	[2..570]	[9..589]

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Predicted Domain #1

Region A:
Residues: [1-571]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSMSSKNENK ISVEQRISTD IGQAYQLQGL GSNLRSIRSK TGAGEVNYID AAKSVNDNQL  60
   61 LAEIGYKQEL KRQFSTLQVF GIAFSIMGLL PSIASVMGGG LGGGPATLVW GWFVAAFFIL 120
  121 LVGITMAEHA SSIPTAGGLY YWTYYYAPEG YKEIISFIIG CSNSLALAAG VCSIDYGLAE 180
  181 EIAAAVTLTK DGNFEVTSGK LYGIFAGAVV VMCICTCVAS GAIARLQTLS IFANLFIIVL 240
  241 LFIALPIGTK HRMGGFNDGD FIFGKYENLS DWNNGWQFCL AGFMPAVWTI GSFDSCVHQS 300
  301 EEAKDAKKSV PIGIISSIAV CWILGWLIII CLMACINPDI DSVLDSKYGF ALAQIIYDSL 360
  361 GKKWAIAFMS LIAFCQFLMG ASITTAVSRQ VWAFSRDNGL PLSKYIKRVD SKYSVPFFAI 420
  421 LAACVGSLIL GLLCLIDDAA TDALFSLAVA GNNLAWSTPT VFRLTSGRDL FRPGPFYLGK 480
  481 IWSPIVAWTG VAFQLFIIIL VMFPSQQHGI TKSTMNYACV IGPGIWILAG IYYKVYKKKY 540
  541 YHGPATNLSD DDYTEAVGAD VIDTIMSKQE P

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	5.853872
Match:	PF00324
Description:	Amino acid permease

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [67-571]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KQELKRQFST LQVFGIAFSI MGLLPSIASV MGGGLGGGPA TLVWGWFVAA FFILLVGITM  60
   61 AEHASSIPTA GGLYYWTYYY APEGYKEIIS FIIGCSNSLA LAAGVCSIDY GLAEEIAAAV 120
  121 TLTKDGNFEV TSGKLYGIFA GAVVVMCICT CVASGAIARL QTLSIFANLF IIVLLFIALP 180
  181 IGTKHRMGGF NDGDFIFGKY ENLSDWNNGW QFCLAGFMPA VWTIGSFDSC VHQSEEAKDA 240
  241 KKSVPIGIIS SIAVCWILGW LIIICLMACI NPDIDSVLDS KYGFALAQII YDSLGKKWAI 300
  301 AFMSLIAFCQ FLMGASITTA VSRQVWAFSR DNGLPLSKYI KRVDSKYSVP FFAILAACVG 360
  361 SLILGLLCLI DDAATDALFS LAVAGNNLAW STPTVFRLTS GRDLFRPGPF YLGKIWSPIV 420
  421 AWTGVAFQLF IIILVMFPSQ QHGITKSTMN YACVIGPGIW ILAGIYYKVY KKKYYHGPAT 480
  481 NLSDDDYTEA VGADVIDTIM SKQEP

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.4
Match:	2a65A
Description:	Crystal structure of LEUTAA, a bacterial homolog of Na+/Cl--dependent neurotransmitter transporters
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits