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Protein Overview: RDI1

General Information:
Name(s) found: RDI1 / YDL135C [SGD]
Description(s) found:
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  • gi|6320066|ref|NP_010146.1| Rho GDP dissociation inhibitor involved in the localization and regulation of Cdc42p; Rdi1p [Saccharomyces cerevisiae] [NCBI NR]
  • pir||A53646 rho GDP dissociation inhibitor - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • gi|516857|dbj|BAA06499.1| rho GDP dissociation inhibitor [Saccharomyces cerevisiae] [NCBI NR]
  • gi|45270220|gb|AAS56491.1| YDL135C [Saccharomyces cerevisiae] [NCBI NR]
  • gi|2494706|sp|Q12434.1|GDIR_YEAST RecName: Full=Rho GDP-dissociation inhibitor; Short=Rho GDI [NCBI NR]
  • gi|1431207|emb|CAA98708.1| RDI1 [Saccharomyces cerevisiae] [NCBI NR]
  • gi|1419226|emb|CAA65624.1| rho GDP dissociation factor [Saccharomyces cerevisiae] [NCBI NR]
  • Rho GDP-dissociation inhibitor OS=Saccharomyces cerevisiae GN=RDI1 PE=1 SV=1 [Swiss-Prot]
  • RDI1 Rho GDP dissociation inhibitor with activity toward Rho1p [mips]
  • Rho GDP dissociation inhibitor involved in the localization and regulation of Cdc42p [SGD]
  • RDI1, Chr IV from 218680-219288, reverse complement [yeast_orfs2]
  • Chr IV from 218680-219288, reverse complement [yeastorf3.fasta]
  • Chr IV from 219288-218680, reverse complement [yeastorf5.fasta]
  • (Q12434) Rho GDP-dissociation inhibitor (Rho GDI) [4932.FASTACCERV.txt]
  • RDI1 SGDID:S0002294, Chr IV from 219288-218680, reverse complement, Verified ORF [yeastflysequest.fasta]
  • Rdi1p [Saccharomyces cerevisiae]gi|1419226|emb|CAA65624.1| rho GDP dissociation factor [Saccharomyces cerevisiae]gi|1431207|emb|CAA98708.1| RDI1 [Saccharomyces cerevisiae]gi|516857|dbj|BAA06499.1| rho GDP dissociation inhibitor [Saccharomyces cerevisia [nrdb_11152004_Chlamydomonas]
  • RDI1 SGDID:S000002294, Chr IV from 219288-218680, reverse complement, Verified ORF, "Rho GDP dissociation inhibitor involved in the localization and regulation of Cdc42p" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • YDL135C [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • rho GDP dissociation inhibitor [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • RDI1 [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • Rho GDP-dissociation inhibitor (Rho GDI) [nr-271106-contam.fasta]
  • Rho GDP dissociation inhibitor involved in the localization and regulation of Cdc42p; Rdi1p [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • rho GDP dissociation factor [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • [chemostatdb.fasta]
  • Rho GDP-dissociation inhibitor OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RDI1 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • RDI1 SGDID:S000002294, Chr IV from 219288-218680, Genome Release 64-1-1, reverse complement, Verified ORF, "Rho GDP dissociation inhibitor involved in the localization and regulation of Cdc42p and Rho1p" [yeast-030211-contam.fasta]
  • RDI1 SGDID:S000002294, Chr IV from 219288-218680, Genome Release 64-2-1, reverse complement, Verified ORF, "Rho GDP dissociation inhibitor; involved in the localization and regulation of Cdc42p and Rho1p; protein abundance increases in response to DNA replication stress" [20141208_orf_trans.fasta]
  • TR4993|c0_g1_i1|g.3327 ORF TR4993|c0_g1_i1|g.3327 TR4993|c0_g1_i1|m.3327 type:complete len:203 (+) TR4993|c0_g1_i1:187-795(+) [DBVPG6044_S_cerevisiae-Sep2015-contam.fasta]
  • YDL135C SGDID:S000002294, Chr IV from 219288-218680, Genome Release 64-1-1, reverse complement, Verified ORF, "Rho GDP dissociation inhibitor involved in the localization and regulation of Cdc42p and Rho1p" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
  • asmbl_1109|g.523 ORF asmbl_1109|g.523 asmbl_1109|m.523 type:complete len:203 (+) asmbl_1109:176-784(+) [DBVPG6044_Trinity_v2_2_0_PASA_6May2016-contam.fasta]
  • ID=asmbl_1111|g.659 ORF ID=asmbl_1111|g.659 ID=asmbl_1111|m.659 type:complete len:203 (+) ID=asmbl_1111:176-784(+) [DBVPG6044_quiverGenomes_Trinity_v2_2_0_PASA_2June2016-contam.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 202 amino acids

    Gene Ontology:
    Cellular Component: cellular bud tip [IDALink to PubMed article]
    cellular bud neck [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: small GTPase mediated signal transduction [IPILink to PubMed article]
    actin filament organization [IDALink to PubMed article][IMPLink to PubMed article]
    Molecular Function: Rho GDP-dissociation inhibitor activity [IDALink to PubMed article]
    signal transducer activity [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEESTDFSQ FEEERNNDQY KVSAKKTVDE YKNLDAEDES LAKWKESLGL SSDVLPLEFP  60
   61 GDKRKVVVQK IQLLVNTEPN PITFDLTNEK TIKELASKRY KIKENSIYKL KIVFKVQHEI 120
  121 ITGLRYVQYI KKAGIAVDKI DDHLGSYAPN TKTKPFYEVE LPESEAPSGF LARGNYSAVS 180
  181 KFIDDDKTNH LTLNWGVEIV KK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data RDI1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..202] PSI-BLAST 376.450636 Rho GDP-dissociation inhibitor 1, RhoGDI

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • actin binding
    		•  4.21900602727099 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  3.82728537491772 bayes_pls_golite062009
  • voltage-gated cation channel activity
    		•  2.79599274364249 bayes_pls_golite062009
  • voltage-gated ion channel activity
    		•  2.7120102542099 bayes_pls_golite062009
  • voltage-gated channel activity
    		•  2.70863932585459 bayes_pls_golite062009
  • potassium channel activity
    		•  2.69685666968196 bayes_pls_golite062009
  • voltage-gated potassium channel activity
    		•  2.69627305312298 bayes_pls_golite062009
  • binding
    		•  2.65544526722793 bayes_pls_golite062009
  • cation channel activity
    		•  2.65302958856525 bayes_pls_golite062009
  • gated channel activity
    		•  2.52278796517374 bayes_pls_golite062009
  • transporter activity
    		•  2.46466249895824 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.37642404692102 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.37262306131842 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  2.32502571419352 bayes_pls_golite062009
  • channel activity
    		•  2.3181005726144 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  2.3181005726144 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  2.31677709260544 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  2.28077016868353 bayes_pls_golite062009
  • ion channel activity
    		•  2.2553711462771 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  2.23522391314947 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  2.15379228421204 bayes_pls_golite062009
  • inward rectifier potassium channel activity
    		•  1.86598930407084 bayes_pls_golite062009
  • ligand-gated ion channel activity
    		•  1.81486809950722 bayes_pls_golite062009
  • ligand-gated channel activity
    		•  1.81486809950722 bayes_pls_golite062009
  • Rho GDP-dissociation inhibitor activity
    		•  1.67374100547551 bayes_pls_golite062009
  • actin filament binding
    		•  1.67203076960313 bayes_pls_golite062009
  • small GTPase regulator activity
    		•  1.55727555528218 bayes_pls_golite062009
  • protein binding
    		•  1.50286160643298 bayes_pls_golite062009
  • GTPase regulator activity
    		•  1.44225801859996 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  1.42486878565247 bayes_pls_golite062009
  • clathrin binding
    		•  1.23902179002817 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.12993648323166 bayes_pls_golite062009
  • signal transducer activity
    		•  1.12993648323166 bayes_pls_golite062009
  • enzyme regulator activity
    		•  1.05880190577068 bayes_pls_golite062009
  • GDP-dissociation inhibitor activity
    		•  0.580608094701522 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle