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Protein Overview: FUI1

General Information:
Name(s) found: FUI1 / YBL042C [SGD]
Description(s) found:
Found 27 descriptions.
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  • High affinity uridine permease, localizes to the plasma membrane; also mediates low but significant transport of the cytotoxic nucleoside analog 5-fluorouridine; not involved in uracil transport [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 639 amino acids

    Gene Ontology:
    Cellular Component: plasma membrane [IGILink to PubMed article][IMPLink to PubMed article]
    Biological Process: uridine transport [IGILink to PubMed article][IMPLink to PubMed article]
    Molecular Function: uridine transmembrane transporter activity [IGILink to PubMed article][IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPVSDSGFDN SSKTMKDDTI PTEDYEEITK ESEMGDATKI TSKIDANVIE KKDTDSENNI  60
   61 TIAQDDEKVS WLQRVVEFFE VKNDSTDLAD HKPENPIRTF KDLQESLRST YLYNTDLRPV 120
  121 EAKRRTWTWK QYIFFWISGS FNVNTWQISA TGLQLGLNWW QTWICIWVGY TFVAFFLILG 180
  181 SKVGNNYHIS FPISSRVSFG IYFSIWIVIN RVVMACVWNS TLAYIGSQCV QLMLKAIFGT 240
  241 NLNTRIKDTI KNPNLTNFEF MCFMVFWVAC LPFLWFPPDK LRHIFALKSA ITPFAAFGFL 300
  301 IWTLCKAKGH LALGSLNDNG GAISKTVLAW SVIRAIMSAL DNFSTLILNA PDFTRFGKTY 360
  361 KSSVYSQLIA LPVCYAIISL IGILSVSAAY TLYGVNYWSP LDILNRYLDN YTSGNRAGVF 420
  421 LISFIFAFDQ LGANLSGNSI PAGTDLTALL PKFINIRRGS YICALISLAI CPWDLLSSSS 480
  481 KFTTALAAYA VFLSAIAGVI SADYFIVRKG YVNIFHCYTD KPGSYYMYNK YGTNWRAVVA 540
  541 YIFGIAPNFA GFLGSVGVSV PIGAMKVYYL NYFVGYLLAA LSYCILVYFY PIKGIPGDAK 600
  601 ITDRKWLEEW VEVEEFGTER EAFEEYGGVS TGYEKIRYI

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) FCY2 FUI1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data FUI1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..83] deduced N/A Confident ab initio structure predictions are available.
    2 View Details [84..639] Pfam 229.69897 Permease for cytosine/purines, uracil, thiamine, allantoin No confident structure predictions are available.
    3 View Details [561..639] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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