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Protein Overview: eps-8

General Information:
Name(s) found: eps-8 / CE39449 [WormBase]
Description(s) found:
Found 11 descriptions.
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  • WBGene00001330 locus:eps-8 status:Confirmed UniProt:Q7YTG2 protein_id:CAE45094.2 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 665 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article]
    brush border [IDALink to PubMed article]
    Biological Process: locomotory behavior [IMPLink to PubMed articleLink to PubMed article]
    nematode larval development [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed articleLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    growth [IMPLink to PubMed articleLink to PubMed article]
    Molecular Function: sequence-specific DNA binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPFYPPDDAS ISSETSEMFE RDVNTLNRCF DDIERFVARI QSAALAQREI EQQNHRYRTA  60
   61 NRRDKKNQQP PDPNGILFMR AQLPLESEFV DILKKFKLSF NLLAKLKNHI HEPNAPELLH 120
  121 FLFTPLAVIL EACHWGLGRN VAPTVASPLL SLEARELMQN CLTSHESDIW MSLGEAWRTP 180
  181 PEDWTKPLPP PYRPIFNDGF APYGVADRAM ATPNQIHRGH SAPPEHFRQP PPRERNMVDT 240
  241 LEFDRLTLER ERLEFEKAKI MERESRLRHE EKQIEDEKRR MHAEKDLITK ETTQPVPPPA 300
  301 AVVTHQPITK RYDPPISISP PPQRNNYSHV KVTVDSDTSP RQQAFIDDIV AKGGKLAVVT 360
  361 YDRGGQNTKE LTVHKGEYLE VIFDERNWWE CKNMHQRVGY VPHTILSMVP FEQQQYASPN 420
  421 HHNNSSSTGG YNNGHHQGPA QNVYRPPPPP LVSDAGVQVE IRREHVAPPP PPVVIPPPPP 480
  481 PVRTPTMEEL LRMQQQQQQK QRKPPVEEPV YQPQPAQRAG LEIWRRNQNP QLIQEVTETV 540
  541 GQHSGDILRP AMQRATRVAI NEKSSPEDVT RWLQEKGFSP RVIDLLDGQD GANLFSLSKL 600
  601 HLQQACGRDE GGYLYSQLLV QKKRSGFRTH TGDELKAILN HRRTHVELSN EAAADEPVFT 660
  661 INPIL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..173] MSA 1.043964 View MSA. No confident structure predictions are available.
    2 View Details [174..233] deduced N/A No confident structure predictions are available.
    3 View Details [234..472] PSI-BLAST 17.522879 No description for 2eyzA was found.
    4 View Details [473..559] PSI-BLAST 21.69897 Growth factor receptor-bound protein 2 (GRB2), N- and C-terminal domains; Growth factor receptor-bound protein 2 (GRB2)
    5 View Details [560..665] PSI-BLAST 22.0 No description for 2e8mA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • binding
    		•  0.375837873453985 bayes_pls_golite062009
  • protein binding
    		•  0.25580402341401 bayes_pls_golite062009
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle