Protein Overview: FRDB_ECOLI

General Information:
Name(s) found:	FRDB_ECOLI [Swiss-Prot]
Description(s) found: Found 17 descriptions. SHOW ALL	Fumarate reductase iron-sulfur subunit (EC 1.3.99.1) - Escherichia coli [Swiss-Prot]
Organism:	Escherichia coli
Length:	244 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEMKNLKIE VVRYNPEVDT APHSAFYEVP YDATTSLLDA LGYIKDNLAP DLSYRWSCRM  60
   61 AICGSCGMMV NNVPKLACKT FLRDYTDGMK VEALANFPIE RDLVVDMTHF IESLEAIKPY 120
  121 IIGNSRTADQ GTNIQTPAQM AKYHQFSGCI NCGLCYAACP QFGLNPEFIG PAAITLAHRY 180
  181 NEDSRDHGKK ERMAQLNSQN GVWSCTFVGY CSEVCPKHVD PAAAIQQGKV ESSKDFLIAT 240
  241 LKPR

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..244]	PSI-BLAST	51.69897	Fumarate reductase; Fumarate reductase iron-sulfur protein, N-terminal domain

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
succinate dehydrogenase (ubiquinone) activity	8.67170708058767	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor	8.67170708058767	bayes_pls_golite062009
electron carrier activity	5.46307392364196	bayes_pls_golite062009
succinate dehydrogenase activity	5.17247395944711	bayes_pls_golite062009
4 iron, 4 sulfur cluster binding	4.95798078106244	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors	4.38887210619429	bayes_pls_golite062009
oxidoreductase activity	4.24568355093737	bayes_pls_golite062009
NADH dehydrogenase activity	4.24327638063454	bayes_pls_golite062009
NADH dehydrogenase (quinone) activity	4.15859537745252	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH	3.78210410787032	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor	3.67682177056786	bayes_pls_golite062009
iron-sulfur cluster binding	3.28424324316751	bayes_pls_golite062009
metal cluster binding	3.28424324316751	bayes_pls_golite062009
binding	1.29066915338738	bayes_pls_golite062009
protein binding	0.507343948317508	bayes_pls_golite062009
catalytic activity	0.105119876745552	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
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