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Protein Overview: E4PD_ECOLI

General Information:
Name(s) found: E4PD_ECOLI [Swiss-Prot]
Description(s) found:
Found 16 descriptions.
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  • D-erythrose-4-phosphate dehydrogenase (EC 1.2.1.72) (E4PDH) - Escherichia coli [Swiss-Prot]
    • Organism: Escherichia coli
    Length: 339 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTVRVAINGF GRIGRNVVRA LYESGRRAEI TVVAINELAD AAGMAHLLKY DTSHGRFAWE  60
   61 VRQERDQLFV GDDAIRVLHE RSLQSLPWRE LGVDVVLDCT GVYGSREHGE AHIAAGAKKV 120
  121 LFSHPGSNDL DATVVYGVNQ DQLRAEHRIV SNASCTTNCI IPVIKLLDDA YGIESGTVTT 180
  181 IHSAMHDQQV IDAYHPDLRR TRAASQSIIP VDTKLAAGIT RFFPQFNDRF EAIAVRVPTI 240
  241 NVTAIDLSVT VKKPVKANEV NLLLQKAAQG AFHGIVDYTE LPLVSVDFNH DPHSAIVDGT 300
  301 QTRVSGAHLI KTLVWCDNEW GFANRMLDTT LAMATVAFR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..339] PSI-BLAST 106.0 Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • glyceraldehyde-3-phosphate dehydrogenase activity
    		•  6.40381118887682 bayes_pls_golite062009
  • glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity
    		•  5.96956214078036 bayes_pls_golite062009
  • oxidoreductase activity
    		•  4.00402564572912 bayes_pls_golite062009
  • 1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
    		•  3.16750187025282 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors
    		•  2.70673476015931 bayes_pls_golite062009
  • catalytic activity
    		•  2.54843319568228 bayes_pls_golite062009
  • glucose-6-phosphate dehydrogenase activity
    		•  2.2713146106379 bayes_pls_golite062009
  • inositol-3-phosphate synthase activity
    		•  2.2178883592085 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.90939908578582 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
    		•  1.66955978224275 bayes_pls_golite062009
  • DNA binding
    		•  1.61355789916908 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.48478425318425 bayes_pls_golite062009
  • hydrolase activity
    		•  1.40468563568607 bayes_pls_golite062009
  • binding
    		•  1.22114607236074 bayes_pls_golite062009
  • retinol dehydrogenase activity
    		•  1.16811519855038 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  1.11682034462164 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  1.03017667696669 bayes_pls_golite062009
  • transcription factor activity
    		•  0.91090893050278 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.910536752370264 bayes_pls_golite062009
  • signal transducer activity
    		•  0.910536752370264 bayes_pls_golite062009
  • alcohol dehydrogenase (NAD) activity
    		•  0.88293430762998 bayes_pls_golite062009
  • NAD or NADH binding
    		•  0.74536049628503 bayes_pls_golite062009
  • intramolecular lyase activity
    		•  0.708206800759221 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  0.527946013169731 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-CH group of donors
    		•  0.41382905800454 bayes_pls_golite062009
  • receptor activity
    		•  0.388215697182664 bayes_pls_golite062009
  • structural molecule activity
    		•  0.345975336806588 bayes_pls_golite062009
  • alcohol dehydrogenase activity, zinc-dependent
    		•  0.331048046502169 bayes_pls_golite062009
  • collagen binding
    		•  0.30621400535957 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  0.211380641599388 bayes_pls_golite062009
  • NADPH:quinone reductase activity
    		•  0.136079082491021 bayes_pls_golite062009
  • glucose binding
    		•  0.13030486887358 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle