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Protein Overview: TRPG_ECOLI

General Information:
Name(s) found: TRPG_ECOLI [Swiss-Prot]
Description(s) found:
Found 7 descriptions.
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  • Anthranilate synthase component II (EC 4.1.3.27) [Includes: Glutamine amidotransferase; Anthranilate phosphoribosyltransferase (EC 2.4.2.18)] - Escherichia coli [Swiss-Prot]
    • Organism: Escherichia coli
    Length: 531 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADILLLDNI DSFTYNLADQ LRSNGHNVVI YRNHIPAQTL IERLATMSNP VLMLSPGPGV  60
   61 PSEAGCMPEL LTRLRGKLPI IGICLGHQAI VEAYGGYVGQ AGEILHGKAS SIEHDGQAMF 120
  121 AGLTNPLPVA RYHSLVGSNI PAGLTINAHF NGMVMAVRHD ADRVCGFQFH PESILTTQGA 180
  181 RLLEQTLAWA QQKLEPANTL QPILEKLYQA QTLSQQESHQ LFSAVVRGEL KPEQLAAALV 240
  241 SMKIRGEHPN EIAGAATALL ENAAPFPRPD YLFADIVGTG GDGSNSINIS TASAFVAAAC 300
  301 GLKVAKHGNR SVSSKSGSSD LLAAFGINLD MNADKSRQAL DELGVCFLFA PKYHTGFRHA 360
  361 MPVRQQLKTR TLFNVLGPLI NPAHPPLALI GVYSPELVLP IAETLRVLGY QRAAVVHSGG 420
  421 MDEVSLHAPT IVAELHDGEI KSYQLTAEDF GLTPYHQEQL AGGTPEENRD ILTRLLQGKG 480
  481 DAAHEAAVAA NVAMLMRLHG HEDLQANAQT VLEVLRSGSA YDRVTALAAR G

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..195] PSI-BLAST 42.09691 Anthranilate synthase GAT subunit, TrpG
    2 View Details [196..531] PSI-BLAST 90.69897 Anthranilate phosphoribosyltransferase (TrpD)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • 4-amino-4-deoxychorismate synthase activity
    		•  4.48164623771604 bayes_pls_golite062009
  • anthranilate synthase activity
    		•  2.51214170411838 bayes_pls_golite062009
  • ligase activity
    		•  1.77692713123297 bayes_pls_golite062009
  • oxo-acid-lyase activity
    		•  1.35896725827905 bayes_pls_golite062009
  • catalytic activity
    		•  1.30391542469987 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  0.628648036096965 bayes_pls_golite062009
  • imidazoleglycerol-phosphate synthase activity
    		•  0.270391651600004 bayes_pls_golite062009
  • carbon-carbon lyase activity
    		•  0.0769356405014503 bayes_pls_golite062009
    2
    Term Confidence Notes
  • anthranilate phosphoribosyltransferase activity
    		•  4.81240054558791 bayes_pls_golite062009
  • transferase activity, transferring pentosyl groups
    		•  2.10935430322097 bayes_pls_golite062009
  • catalytic activity
    		•  1.99182579317454 bayes_pls_golite062009
  • transferase activity
    		•  1.24273940197065 bayes_pls_golite062009
  • transferase activity, transferring glycosyl groups
    		•  1.10712828233974 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle