Protein Overview: EG10242

General Information:
Name(s) found:	dnaN / EG10242 [EcoGene]
Description(s) found: SHOW ONLY BEST	DNA polymerase III, beta subunit / DNA polymerase III sliding clamp beta subunit; required for high processivity; required for regulatory inactivation of DnaA [EcoGene] DNA polymerase III, beta subunit [Escherichia coli K12] [nr-271106-contam.fasta] DNA polymerase III subunit beta [Escherichia coli K12] [nr-271106-contam.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] DNA polymerase III, beta subunit [Escherichia coli str. K-12 substr. MG1655] [Ecoli-contam-Dam1-Mind-COMA-MBP-110.fasta]
Organism:	Escherichia coli str. K-12 substr. MG1655
Length:	366 amino acids
Gene Ontology:
Cellular Component:	cytosol [IDA]
Biological Process:	DNA replication [IEA]
Molecular Function:	3'-5' exonuclease activity [IEA] DNA binding [IEA] nucleotidyltransferase activity [IEA] DNA-directed DNA polymerase activity [IEA] protein binding [IPI ] transferase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKFTVEREHL LKPLQQVSGP LGGRPTLPIL GNLLLQVADG TLSLTGTDLE MEMVARVALV  60
   61 QPHEPGATTV PARKFFDICR GLPEGAEIAV QLEGERMLVR SGRSRFSLST LPAADFPNLD 120
  121 DWQSEVEFTL PQATMKRLIE ATQFSMAHQD VRYYLNGMLF ETEGEELRTV ATDGHRLAVC 180
  181 SMPIGQSLPS HSVIVPRKGV IELMRMLDGG DNPLRVQIGS NNIRAHVGDF IFTSKLVDGR 240
  241 FPDYRRVLPK NPDKHLEAGC DLLKQAFARA AILSNEKFRG VRLYVSENQL KITANNPEQE 300
  301 EAEEILDVTY SGAEMEIGFN VSYVLDVLNA LKCENVRMML TDSVSSVQIE DAASQSAAYV 360
  361 VMPMRL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

Term	Confidence	Notes
DNA-directed DNA polymerase activity	10.1355867012964	bayes_pls_golite062009
DNA polymerase activity	10.0862166288891	bayes_pls_golite062009
nucleotidyltransferase activity	7.50006430161592	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	3.53479307306028	bayes_pls_golite062009
transferase activity	2.88122926655527	bayes_pls_golite062009
binding	0.65029295764999	bayes_pls_golite062009
DNA polymerase processivity factor activity	0.616404933041	bayes_pls_golite062009
catalytic activity	0.48077242755678	bayes_pls_golite062009
nucleic acid binding	0.4343174930339	bayes_pls_golite062009
DNA binding	0.129085697705275	bayes_pls_golite062009

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.97

Source: Reynolds et al. (2008)

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..366]	PSI-BLAST	125.0	E. COLI DNA POLYMERASE BETA SUBUNIT

Protein Overview: EG10242

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: