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View Structure Prediction Details

Protein: par-1-PG
Organism: Drosophila melanogaster
Length: 1138 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for par-1-PG.

Description E-value Query
Range
Subject
Range
gi|16197787 - gi|16197787|gb|AAL13494.1| GH01890p [Drosophila melanogaster]
659.0 [0..67] [1138..1]

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Predicted Domain #1
Region A:
Residues: [1-208]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEATTTTTPD LNRGDATRKS VRLYAARKGA APAPPKLSVA PSSNQNSNHS SNNNNSSSNL  60
   61 PETEKEMELR QTHLANKDLD GATEDDSIVE LRRRDAQATP LPRIAVSALP TLQPHPTPKE 120
  121 RQKPPMPRLL STEDDAGVSF ALGSIEKHIH NVEESFKQQQ QNQQSQSSMD VMKLEIKRKQ 180
  181 SKRYGETENL LRPGISDMSS ENDFQYLG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [209-363]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GRRAGELDDS NELMLSEFQR GSDGRNSIGA YSKNSAAAAN GANAVKAKLA RTASDTKNND  60
   61 TVLAMRATFK QKQHLQDEKQ PAVWRPAGTG PTPAARSSSS TTSTSGSASR GGSSSSVVDG 120
  121 VAPSKLTATT ISASKRREEN LRQFEALLAQ KSSHR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [364-744]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HGASGASGTG SNAASSKRRS DRPIVAPIPP YNSSRAEHVT SSTRHSVDPR SHSGHESRSG  60
   61 TASTHPPVGH HPTSRVPSVV ANRSNVYSNN AAQGSPNMQM RSSAPMRWRA TEEHIGKYKL 120
  121 IKTIGKGNFA KVKLAKHLPT GKEVAIKIID KTQLNPGSLQ KLFREVRIMK MLDHPNIVKL 180
  181 FQVIETEKTL YLIMEYASGG EVFDYLVLHG RMKEKEARVK FRQIVSAVQY CHQKRIIHRD 240
  241 LKAENLLLDS ELNIKIADFG FSNEFTPGSK LDTFCGSPPY AAPELFQGKK YDGPEVDVWS 300
  301 LGVILYTLVS GSLPFDGSTL RELRERVLRG KYRIPFYMST DCENLLRKFL VLNPAKRASL 360
  361 ETIMGDKWMN MGFEEDELKP Y

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 45.221849
Match: 2ozoA
Description: No description for 2ozoA was found.

Predicted Domain #4
Region A:
Residues: [745-829]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IEPKADLADP KRIEALVAMG YNRSEIEASL SQVRYDDVFA TYLLLGRKST DPESDGSRSG  60
   61 SSLSLRNISG NDAGANAGSA SVQSP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 100.0
Match: 2qnjA
Description: No description for 2qnjA was found.

Predicted Domain #5
Region A:
Residues: [830-1053]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 THRGVHRSIS ASSTKPSRRA SSGAETLRVG PTNAAATVAA ATGAVGAVNP SNNYNAAGSA  60
   61 ADRASVGSNF KRQNTIDSAT IKENTARLAA QNQRPASATQ KMLTTADTTL NSPAKPRTAT 120
  121 KYDPTNGNRT VSGTSGIIPR RSTTLYEKTS STEKTNVIPA ETKARNNTAL EYSGTSGASG 180
  181 DSSHPGRMSF FSKLSSRFSK RPTIADEAAK PRVLRFTWSM KTTS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [1054-1138]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLMPDQIMQK IREVLDQNNC DYEQRERFVL WCVHGDPNTD SLVQWEIEVC KLPRLSLNGV  60
   61 RFKRISGTSI GFKNIASRIA FDLKL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 38.0
Match: 1ul7A
Description: Solution structure of kinase associated domain 1 of mouse MAP/microtubule affinity-regulating kinase 3
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein kinase activity 4.05475891009228 bayes_pls_golite062009
protein serine/threonine kinase activity 3.7974128326421 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 3.59230737331367 bayes_pls_golite062009
kinase activity 3.41737435609334 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 3.2342722637405 bayes_pls_golite062009
binding 2.41732321506551 bayes_pls_golite062009
transferase activity 2.04713540681686 bayes_pls_golite062009
ATP binding 1.44435058039859 bayes_pls_golite062009
adenyl ribonucleotide binding 1.41005152726625 bayes_pls_golite062009
adenyl nucleotide binding 1.38971642420542 bayes_pls_golite062009
ribonucleotide binding 1.16863558166547 bayes_pls_golite062009
purine ribonucleotide binding 1.16859376715941 bayes_pls_golite062009
purine nucleotide binding 1.15633908642115 bayes_pls_golite062009
nucleotide binding 1.14964488472581 bayes_pls_golite062009
AMP-activated protein kinase activity 1.12923456567012 bayes_pls_golite062009
catalytic activity 0.836142537655721 bayes_pls_golite062009
protein binding 0.704339182896017 bayes_pls_golite062009
magnesium ion binding 0.439688030503848 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle