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View Structure Prediction Details

Protein: APC7-PA
Organism: Drosophila melanogaster
Length: 615 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for APC7-PA.

Description E-value Query
Range
Subject
Range
gi|113475191, gi... - gi|113475191|ref|YP_721252.1| glycosyl transferase family protein [Trichodesmium erythraeum IMS101],...
397.0 [0..1] [604..34]

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Predicted Domain #1
Region A:
Residues: [1-139]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASFLIVVEK MEIALFANAK KLYDHKLYEC VIPAADLLRT VLKNDRYVAT LDVEYQVLLY  60
   61 LLNANYKERN YRAALRHFDE IIHKRRLMMR HKNAVLVAIE SSYPEFGDAE QRRRAAECYR 120
  121 QIGNTDMAIE TLLQVPPTL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.69897
Match: 1ouvA
Description: Helicobacter cysteine rich protein C (HcpC)
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [140-538]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RSPRINLMLA RLQHHGSRHG TTKKSEAVLA YKEVIRECPM ALQVIEALLE LGVNGNEINS  60
   61 LVMHAATVPD HFDWLSKWIK ALAQMFNFKH SDASQTFLML HDNTTLRCNE HLMMALGKCL 120
  121 YYNGDYFQAE DIFSSTLCAN PDNVEAIGLM AVLCGQEGGC EQDSADMDYL FAKVSSEVKY 180
  181 TASHWFAHAQ LLYDEGKFER GLNFVEKCLD SEPRNHEALI LRGRLLIALE RHTQAVCAFR 240
  241 TAQMVAPYRF EIYRGLFHSY LAQKRFKEAN ALCNWTIRLF QNSPRSFTMF GRTLFLFPDP 300
  301 RMRRTARKFA EKSLKINHIY TPAVNLIADI CQVEGPTKAI IKLLEKHVII FPKVNLLNHL 360
  361 GDIMRKQKEP VKAMEYYYKA LRQDPKSKRT LRGLRLLAK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 58.522879
Match: 1w3bA
Description: The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.52126334054344 bayes_pls_golite062009
protein binding 1.52807685989528 bayes_pls_golite062009
enzyme binding 0.44905827271946 bayes_pls_golite062009
nucleic acid binding 0.41706917101675 bayes_pls_golite062009
transcription regulator activity 0.322371143360832 bayes_pls_golite062009
hydrolase activity 0.252678932946087 bayes_pls_golite062009
small conjugating protein ligase activity 0.244038930707726 bayes_pls_golite062009
ubiquitin-protein ligase activity 0.215617899962405 bayes_pls_golite062009
DNA binding 0.17736976899009 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [539-615]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SDDESPVLDE SDDIGMDNQQ SINDLTTLCE ATNAQGAEGA ESVENSREAS SSAAARSGQE  60
   61 EDVDEHDWID VPDGMSY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.522879
Match: 2j9qA
Description: No description for 2j9qA was found.

YRC Informatics Platform - Version 3.0
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