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View Structure Prediction Details

Protein: gi|9714268, gi|1...
Organism: Homo sapiens
Length: 702 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|9714268, gi|1....

Description E-value Query
Range		 Subject
Range
gi|5762313 - gi|5762313|gb|AAD51098.1| nuclear factor associated with dsRNA NFAR-1 [Homo sapiens]
 0.0 [1..702] [1..702]
gi|111607436, gi... - gi|71044413|gb|AAZ20652.1| nuclear factor 90 [Mus musculus], gi|111607436|ref|NP_001036174.1| interl...
 0.0 [1..702] [1..703]
gi|114675409 - gi|114675409|ref|XP_001166345.1| PREDICTED: interleukin enhancer binding factor 3 isoform 5 [Pan tro...
 0.0 [1..702] [1..706]

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Predicted Domain #1
Region A:
Residues: [1-391] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRPMRIFVND DRHVMAKHSS VYPTQEELEA VQNMVSHTER ALKAVSDWID EQEKGSSEQA  60
   61 ESDNMDVPPE DDSKEGAGEQ KTEHMTRTLR GVMRVGLVAK GLLLKGDLDL ELVLLCKEKP 120
  121 TTALLDKVAD NLAIQLAAVT EDKYEILQSV DDAAIVIKNT KEPPLSLTIH LTSPVVREEM 180
  181 EKVLAGETLS VNDPPDVLDR QKCLAALASL RHAKWFQARA NGLKSCVIVI RVLRDLCTRV 240
  241 PTWGPLRGWP LELLCEKSIG TANRPMGAGE ALRRVLECLA SGIVMPDGSG IYDPCEKEAT 300
  301 DAIGHLDRQQ REDITQSAQH ALRLAAFGQL HKVLGMDPLP SKMPKKPKNE NPVDYTVQIP 360
  361 PSTTYAITPM KRPMEEDGEE KSPSKKKKKI Q

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.94
Match: 1px5A
Description: Crystal structure of the 2'-specific and double-stranded RNA-activated interferon-induced antiviral protein 2'-5'-oligoadenylate synthetase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.0967966107058 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.568291021783733 bayes_pls_golite062009
cytoskeletal protein binding 0.512852377741257 bayes_pls_golite062009
nucleotidyltransferase activity 0.378944807711308 bayes_pls_golite062009
protein binding 0.177198796887481 bayes_pls_golite062009
transferase activity 0.02609645275331 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [392-465] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KKEEKAEPPQ AMNALMRLNQ LKPGLQYKLV SQTGPVHAPI FTMSVEVDGN SFEASGPSKK  60
   61 TAKLHVAVKV LQDM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.30103
Match: 2dmyA
Description: No description for 2dmyA was found.

Predicted functions:

Term Confidence Notes
binding 2.85876367411468 bayes_pls_golite062009
nucleic acid binding 1.47797565464292 bayes_pls_golite062009
protein binding 1.45612186272752 bayes_pls_golite062009
RNA binding 0.728830513014366 bayes_pls_golite062009
cytoskeletal protein binding 0.608351833047597 bayes_pls_golite062009
double-stranded RNA binding 0.486416546047936 bayes_pls_golite062009
DNA binding 0.231787740716432 bayes_pls_golite062009
tubulin binding 0.0967166438103781 bayes_pls_golite062009
microtubule binding 0.0936187743249679 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [466-595] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GLPTGAEGRD SSKGEDSAEE TEAKPAVVAP APVVEAVSTP SAAFPSDATA EQGPILTKHG  60
   61 KNPVMELNEK RRGLKYELIS ETGGSHDKRF VMEVEVDGQK FQGAGSNKKV AKAYAALAAL 120
  121 EKLFPDTPLA

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 4.06
Match: 1qu6A
Description: dsRNA-dependent protein kinase pkr
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.72994153207409 bayes_pls_golite062009
protein binding 1.36091923951901 bayes_pls_golite062009
nucleic acid binding 1.29586026296723 bayes_pls_golite062009
cytoskeletal protein binding 0.600021977124743 bayes_pls_golite062009
RNA binding 0.416434097640643 bayes_pls_golite062009
DNA binding 0.184635431648199 bayes_pls_golite062009
tubulin binding 0.0442753884060716 bayes_pls_golite062009
microtubule binding 0.0314632333581821 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [596-702] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LDANKKKRAP VPVRGGPKFA AKPHNPGFGM GGPMHNEVPP PPNLRGRGRG GSIRGRGRGR  60
   61 GFGGANHGGY MNAGAGYGSY GYGGNSATAG YSDFFTDCYG YHDFGSS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.0
Match: 1zy7A
Description: Crystal structure of the catalytic domain of an adenosine deaminase that acts on RNA (hADAR2) bound to inositol hexakisphosphate (IHP)
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle