YRC Public Data Repository - Protein Structure Prediction

Protein:	YTFL_ECOLI
Organism:	Escherichia coli
Length:	447 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YTFL_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|17134355, gi\|... - gi\|17232708\|ref\|NP_489256.1\| hypothetical protein alr5216 [Nostoc sp. PCC 7120], gi\|17134355\|dbj\|BAB... gi\|25302934 - pir\|\|AH2457 hypothetical protein alr5216 [imported] - Nostoc sp. (strain PCC 7120)	363.0	[0..1]	[436..4]
gi\|16763227 - gi\|16763227\|ref\|NP_458844.1\| hypothetical protein STY4766 [Salmonella enterica subsp. enterica serov... gi\|29144706, gi\|... - gi\|29144706\|ref\|NP_808048.1\| hypothetical protein t4461 [Salmonella enterica subsp. enterica serovar... gi\|161617684, gi... - gi\|161617684\|ref\|YP_001591649.1\| hypothetical protein SPAB_05547 [Salmonella enterica subsp. enteric... gi\|62182852, gi\|... - gi\|62182852\|ref\|YP_219269.1\| hypothetical protein SC4282 [Salmonella enterica subsp. enterica serova... gi\|56130457, gi\|... - gi\|56416200\|ref\|YP_153275.1\| hypothetical protein SPA4227 [Salmonella enterica subsp. enterica serov... gi\|214002811 - gi\|214002811\|ref\|ZP_03413546.1\| putative transporter [Salmonella enterica subsp. enterica serovar Ty... gi\|224586249, gi... - gi\|224586249\|ref\|YP_002640048.1\| hypothetical protein SPC_4557 [Salmonella enterica subsp. enterica ... gi\|213163570 - gi\|213163570\|ref\|ZP_03349280.1\| putative transporter [Salmonella enterica subsp. enterica serovar Ty... gi\|213423664 - gi\|213423664\|ref\|ZP_03356644.1\| putative transporter [Salmonella enterica subsp. enterica serovar Ty... gi\|213585865 - gi\|213585865\|ref\|ZP_03367691.1\| putative transporter [Salmonella enterica subsp. enterica serovar Ty... gi\|213649714 - gi\|213649714\|ref\|ZP_03379767.1\| putative transporter [Salmonella enterica subsp. enterica serovar Ty... gi\|197213826, gi... - gi\|197250123\|ref\|YP_002149321.1\| putative transporter [Salmonella enterica subsp. enterica serovar A... gi\|197262870, gi... - gi\|197262870\|ref\|ZP_03162944.1\| putative transporter [Salmonella enterica subsp. enterica serovar Sa... gi\|197365123, gi... - gi\|197365123\|ref\|YP_002144760.1\| hypothetical protein SSPA3926 [Salmonella enterica subsp. enterica ... gi\|198245725, gi... - gi\|198245725\|ref\|YP_002218289.1\| putative transporter [Salmonella enterica subsp. enterica serovar D... gi\|167991182, gi... - gi\|205330362\|gb\|EDZ17126.1\| putative transporter [Salmonella enterica subsp. enterica serovar 4,[5],... gi\|205337049, gi... - gi\|205337049\|gb\|EDZ23813.1\| putative transporter [Salmonella enterica subsp. enterica serovar Heidel... gi\|16422969, gi\|... - gi\|16767653\|ref\|NP_463268.1\| putative hemolysin-like protein [Salmonella typhimurium LT2], gi\|164229... gi\|205342349, gi... - gi\|205342349\|gb\|EDZ29113.1\| putative transporter [Salmonella enterica subsp. enterica serovar Weltev... gi\|25302926, gi\|... - gi\|25302926\|pir\|\|AB1055 probable membrane protein ytfL [imported] - Salmonella enterica subsp. enter... gi\|194451631, gi... - gi\|194451631\|ref\|YP_002048449.1\| putative transporter [Salmonella enterica subsp. enterica serovar H... lcl\|NC_016856.1_... - [gene=ytfL] [protein=putative hemolysin-like protein] [protein_id=YP_005240724.1] [location=compleme...	358.0	[0..1]	[447..1]
gi\|193063674, gi... - gi\|193063674\|ref\|ZP_03044762.1\| putative transporter [Escherichia coli E22], gi\|192930661\|gb\|EDV8326... gi\|194426533, gi... - gi\|194426533\|ref\|ZP_03059087.1\| putative transporter [Escherichia coli B171], gi\|194415272\|gb\|EDX315... gi\|187730274, gi... - gi\|187730274\|ref\|YP_001882995.1\| putative transporter [Shigella boydii CDC 3083-94], gi\|187427266\|gb... gi\|190902708, gi... - gi\|191167255\|ref\|ZP_03029073.1\| putative transporter [Escherichia coli B7A], gi\|190902708\|gb\|EDV6243... gi\|82779478, gi\|... - gi\|82779478\|ref\|YP_405827.1\| putative transport protein [Shigella dysenteriae Sd197], gi\|81243626\|gb... gi\|81247942, gi\|... - gi\|82546531\|ref\|YP_410478.1\| putative transport protein [Shigella boydii Sb227], gi\|81247942\|gb\|ABB6... gi\|73858176, gi\|... - gi\|74314699\|ref\|YP_313118.1\| putative transport protein [Shigella sonnei Ss046], gi\|73858176\|gb\|AAZ9... gi\|110617584, gi... - gi\|110808036\|ref\|YP_691556.1\| putative transport protein [Shigella flexneri 5 str. 8401], gi\|1106175... gi\|30043754, gi\|... - gi\|30065490\|ref\|NP_839661.1\| putative transport protein [Shigella flexneri 2a str. 2457T], gi\|300437... gi\|157069372, gi... - gi\|157163692\|ref\|YP_001461010.1\| putative transporter [Escherichia coli HS], gi\|157069372\|gb\|ABV0862... gi\|157079304, gi... - gi\|157157274\|ref\|YP_001465725.1\| putative transporter [Escherichia coli E24377A], gi\|157079304\|gb\|AB... gi\|24115470, gi\|... - gi\|24115470\|ref\|NP_709980.1\| putative transport protein [Shigella flexneri 2a str. 301], gi\|24054790... gi\|218697970, gi... - gi\|218697970\|ref\|YP_002405637.1\| conserved hypothetical protein; putative inner membrane protein [Es... gi\|254037238, gi... - gi\|254037238\|ref\|ZP_04871315.1\| conserved hypothetical protein [Escherichia sp. 1_1_43], gi\|22684034... gi\|194433889, gi... - gi\|194433889\|ref\|ZP_03066162.1\| putative transporter [Shigella dysenteriae 1012], gi\|194417870\|gb\|ED... gi\|218556770, gi... - gi\|218556770\|ref\|YP_002389684.1\| conserved hypothetical protein; putative inner membrane protein [Es...	357.0	[0..1]	[447..1]
gi\|89199894, gi\|... - gi\|89199894\|ref\|ZP_01178651.1\| CBS:Protein of unknown function DUF21:Transporter-associated region [...	354.0	[0..2]	[433..3]
gi\|147920421, gi... - gi\|147920421\|ref\|YP_685804.1\| hypothetical protein RCIX1155 [uncultured methanogenic archaeon RC-I],...	353.0	[0..1]	[435..4]
gi\|89155575, gi\|... - gi\|89206454\|ref\|ZP_01185012.1\| CBS:Protein of unknown function DUF21:Transporter-associated region [...	351.0	[0..2]	[433..3]
gi\|75702703, gi\|... - gi\|75908978\|ref\|YP_323274.1\| hypothetical protein Ava_2766 [Anabaena variabilis ATCC 29413], gi\|7570...	349.0	[0..14]	[436..17]
gi\|196031374, gi... - gi\|196038104\|ref\|ZP_03105414.1\| CBS domain protein [Bacillus cereus NVH0597-99], gi\|196031374\|gb\|EDX... gi\|196035498, gi... - gi\|196035498\|ref\|ZP_03102902.1\| CBS domain protein [Bacillus cereus W], gi\|195991799\|gb\|EDX55763.1\| ... gi\|49330819, gi\|... - gi\|49479263\|ref\|YP_037479.1\| hypothetical protein BT9727_3156 [Bacillus thuringiensis serovar konkuk... gi\|118478657, gi... - gi\|118478657\|ref\|YP_895808.1\| hypothetical protein BALH_3041 [Bacillus thuringiensis str. Al Hakam],... gi\|218904507, gi... - gi\|218904507\|ref\|YP_002452341.1\| CBS domain protein [Bacillus cereus AH820], gi\|218538448\|gb\|ACK9084... gi\|225865347, gi... - gi\|225865347\|ref\|YP_002750725.1\| CBS domain protein [Bacillus cereus 03BB102], gi\|225787139\|gb\|ACO27... gi\|196026081, gi... - gi\|196042597\|ref\|ZP_03109836.1\| CBS domain protein [Bacillus cereus 03BB108], gi\|196026081\|gb\|EDX647...	349.0	[0..2]	[424..3]
gi\|68243770, gi\|... - gi\|68549357\|ref\|ZP_00588822.1\| CBS:Protein of unknown function DUF21:Transporter-associated region [...	348.0	[0..4]	[441..22]
gi\|52142176, gi\|... - gi\|52142176\|ref\|YP_084653.1\| hypothetical protein BCZK3066 [Bacillus cereus E33L], gi\|51975645\|gb\|AA...	348.0	[0..2]	[424..3]

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Predicted Domain #1

Region A:
Residues: [1-350]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLNSILVILC LIAVSAFFSM SEISLAASRK IKLKLLADEG NINAQRVLNM QENPGMFFTV  60
   61 VQIGLNAVAI LGGIVGDAAF SPAFHSLFSR YMSAELSEQL SFILSFSLVT GMFILFADLT 120
  121 PKRIGMIAPE AVALRIINPM RFCLYVCTPL VWFFNGLANI IFRIFKLPMV RKDDITSDDI 180
  181 YAVVEAGALA GVLRKQEHEL IENVFELESR TVPSSMTPRE NVIWFDLHED EQSLKNKVAE 240
  241 HPHSKFLVCN EDIDHIIGYV DSKDLLNRVL ANQSLALNSG VQIRNTLIVP DTLTLSEALE 300
  301 SFKTAGEDFA VIMNEYALVV GIITLNDVMT TLMGDLVGQG LEEQIVARDE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	9.69897
Match:	2ooxG
Description:	No description for 2ooxG was found.

Predicted Domain #2

Region A:
Residues: [351-447]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NSWLIDGGTP IDDVMRVLDI DEFPQSGNYE TIGGFMMFML RKIPKRTDSV KFAGYKFEVV  60
   61 DIDNYRIDQL LVTRIDSKAT ALSPKLPDAK DKEESVA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	17.045757
Match:	2p4pA
Description:	No description for 2p4pA was found.

Predicted functions:

Term	Confidence	Notes
magnesium ion transmembrane transporter activity	4.09048700098247	bayes_pls_golite062009
metal ion transmembrane transporter activity	3.20360029620216	bayes_pls_golite062009
ion transmembrane transporter activity	2.84728629370153	bayes_pls_golite062009
cation transmembrane transporter activity	2.83549234777732	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	2.62479915553705	bayes_pls_golite062009
transition metal ion transmembrane transporter activity	2.22305253722734	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	2.09656284183303	bayes_pls_golite062009
transporter activity	1.41639006729672	bayes_pls_golite062009
di-, tri-valent inorganic cation transmembrane transporter activity	1.21441469552217	bayes_pls_golite062009
transmembrane transporter activity	1.13866512878605	bayes_pls_golite062009
substrate-specific transporter activity	0.917464827903503	bayes_pls_golite062009
binding	0.57037105268889	bayes_pls_golite062009
catalytic activity	0.074501016141151	bayes_pls_golite062009
protein binding	0.0511755694922399	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: