YRC Public Data Repository - Protein Structure Prediction

Protein:	YJGH_ECOLI
Organism:	Escherichia coli
Length:	131 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YJGH_ECOLI.

Description	E-value	Query Range	Subject Range
Y854_PYRHO - UPF0076 protein PH0854 OS=Pyrococcus horikoshii GN=PH0854 PE=1 SV=2 Y854_PYRHO - RutC family protein PH0854 OS=Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBR...	160.0	[0..9]	[128..5]
gi\|3257265, gi\|1... - gi\|3257265\|dbj\|BAA29948.1\| 137aa long hypothetical protein [Pyrococcus horikoshii OT3], gi\|14590714\|... gi\|7444996 - gi\|7444996\|pir\|\|B71136 hypothetical protein PH0854 - Pyrococcus horikoshii	160.0	[0..9]	[128..16]
gi\|186685855, gi... - gi\|23127695\|ref\|ZP_00109558.1\| COG1357: Uncharacterized low-complexity proteins [Nostoc punctiforme ...	159.0	[0..2]	[128..301]
RIDA_PYRFU - 2-iminobutanoate/2-iminopropanoate deaminase OS=Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / ...	159.0	[0..4]	[128..2]
gi\|25533215 - pir\|\|AF2289 hypothetical protein all3869 [imported] - Nostoc sp. (strain PCC 7120) gi\|17231361, gi\|... - gi\|17231361\|ref\|NP_487909.1\| hypothetical protein all3869 [Nostoc sp. PCC 7120], gi\|17133003\|dbj\|BAB...	157.0	[0..2]	[131..245]
gi\|89211378, gi\|... - gi\|89211378\|ref\|ZP_01189746.1\| YjgF-like protein [Halothermothrix orenii H 168], gi\|89159023\|gb\|EAR7...	156.0	[0..2]	[128..1]
Y1251_PYRAB, YC5... - (Q9UZA3) Hypothetical UPF0076 protein PYRAB12510, UPF0076 protein PYRAB12510 OS=Pyrococcus abyssi GN... Y1251_PYRAB - RutC family protein PYRAB12510 OS=Pyrococcus abyssi (strain GE5 / Orsay) GN=PYRAB12510 PE=3 SV=1	156.0	[0..2]	[128..1]
gi\|58177560, gi\|... - gi\|58177562\|pdb\|1XRG\|C Chain C, Conserved Hypothetical Protein From Clostridium Thermocellum Cth-296...	155.0	[0..6]	[128..33]
gi\|56378418, gi\|... - gi\|56418576\|ref\|YP_145894.1\| translation initiation inhibitor [Geobacillus kaustophilus HTA426], gi\|... gi\|221088012, gi... - gi\|221088012\|ref\|ZP_03557546.1\| endoribonuclease L-PSP [Geobacillus sp. Y412MC61], gi\|220708005\|gb\|E... gi\|229329342, gi... - gi\|229499758\|ref\|ZP_04393438.1\| endoribonuclease L-PSP [Geobacillus sp. Y412MC52], gi\|229329342\|gb\|E...	155.0	[0..9]	[129..4]
gi\|125975280, gi... - gi\|67874400\|ref\|ZP_00504186.1\| YjgF-like protein [Clostridium thermocellum ATCC 27405], gi\|67851173\|... gi\|196198252, gi... - gi\|196252394\|ref\|ZP_03151053.1\| endoribonuclease L-PSP [Clostridium thermocellum DSM 4150], gi\|19619...	154.0	[0..4]	[128..1]

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Predicted Domain #1

Region A:
Residues: [1-131]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVERTAVFPA GRHSLYAEHR YSAAIRSGDL LFVSGQVGSR EDGTPEPDFQ QQVRLAFDNL  60
   61 HATLAAAGCT FDDIIDVTSF HTDPENQFED IMTVKNEIFS APPYPNWTAV GVTWLAGFDF 120
  121 EIKVIARIPE Q

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	35.522879
Match:	1pf5A
Description:	Structural Genomics, Protein YJGH
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ribonuclease activity	4.29353503464865	bayes_pls_golite062009
endoribonuclease activity	4.17186603647388	bayes_pls_golite062009
endonuclease activity	2.73014048699132	bayes_pls_golite062009
hydrolase activity	1.75421998035125	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	1.58897589345701	bayes_pls_golite062009
catalytic activity	1.37892559560737	bayes_pls_golite062009
nuclease activity	1.12082233513116	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: