YRC Public Data Repository - Protein Structure Prediction

Protein:	FIEF_ECOLI, YIIP...
Organism:	Escherichia coli
Length:	300 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FIEF_ECOLI, YIIP....

Description	E-value	Query Range	Subject Range
FIEF_SALCH - Cation-efflux pump FieF OS=Salmonella choleraesuis (strain SC-B67) GN=fieF PE=3 SV=1 FIEF_SALCH - Cation-efflux pump FieF OS=Salmonella choleraesuis GN=fieF PE=3 SV=1 FIEF_SALCH - Cation-efflux pump fieF OS=Salmonella choleraesuis GN=fieF PE=3 SV=1	238.0	[0..1]	[296..1]
gi\|91213455, gi\|... - gi\|91213455\|ref\|YP_543441.1\| hypothetical protein YiiP [Escherichia coli UTI89], gi\|91075029\|gb\|ABE0... gi\|226902883, gi... - gi\|237702946\|ref\|ZP_04533427.1\| ferrous iron efflux protein F [Escherichia sp. 3_2_53FAA], gi\|226902... gi\|26111111, gi\|... - gi\|26250680\|ref\|NP_756720.1\| ferrous iron efflux protein F [Escherichia coli CFT073], gi\|26111111\|gb...	238.0	[0..1]	[300..15]
gi\|162138317 - gi\|162138317\|ref\|YP_543441.2\| ferrous iron efflux protein F [Escherichia coli UTI89] FIEF_ECOSM - Ferrous-iron efflux pump FieF OS=Escherichia coli (strain SMS-3-5 / SECEC) GN=fieF PE=3 SV=1 FIEF_ECOL5 - Ferrous-iron efflux pump FieF OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=fieF PE=3 SV=1 FIEF_ECOL6 - Ferrous-iron efflux pump FieF OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=fieF... FIEF_ECO7I - Ferrous-iron efflux pump FieF OS=Escherichia coli O7:K1 (strain IAI39 / ExPEC) GN=fieF PE=3 SV=1 FIEF_ECO45 - Ferrous-iron efflux pump FieF OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=fieF PE=3 SV=1 FIEF_ECO81 - Ferrous-iron efflux pump FieF OS=Escherichia coli O81 (strain ED1a) GN=fieF PE=3 SV=1 FIEF_SHISS - Cation-efflux pump FieF OS=Shigella sonnei (strain Ss046) GN=fieF PE=3 SV=1 gi\|190907046, gi... - gi\|75240308\|ref\|ZP_00724248.1\| COG0053: Predicted Co/Zn/Cd cation transporters [Escherichia coli F11... FIEF_ECOK1 - Ferrous-iron efflux pump FieF OS=Escherichia coli O1:K1 / APEC GN=fieF PE=3 SV=1 gi\|56480480, gi\|... - gi\|56480480\|ref\|NP_709720.2\| ferrous iron efflux protein F [Shigella flexneri 2a str. 301], gi\|56384... gi\|227837721, gi... - gi\|227885345\|ref\|ZP_04003150.1\| CDF family cation diffusion facilitator [Escherichia coli 83972], gi... gi\|30064791, gi\|... - gi\|30064791\|ref\|NP_838962.1\| ferrous iron efflux protein F [Shigella flexneri 2a str. 2457T], gi\|300... FIEF_SHIFL - Cation-efflux pump FieF OS=Shigella flexneri GN=fieF PE=3 SV=2 FIEF_ECOL6 - Ferrous-iron efflux pump FieF OS=Escherichia coli O6 GN=fieF PE=3 SV=2	237.0	[0..1]	[300..1]
gi\|83569819, gi\|... - gi\|83569819\|ref\|ZP_00921268.1\| COG0053: Predicted Co/Zn/Cd cation transporters [Shigella dysenteriae...	237.0	[0..1]	[300..1]
FIEF_SHIB3 - Cation-efflux pump FieF OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) GN=fieF PE=3 SV=... FIEF_SHIBS - Cation-efflux pump FieF OS=Shigella boydii serotype 4 (strain Sb227) GN=fieF PE=3 SV=1	237.0	[0..1]	[300..1]
FIEF_SHIF8 - Cation-efflux pump FieF OS=Shigella flexneri serotype 5b (strain 8401) GN=fieF PE=3 SV=1	236.0	[0..1]	[300..1]
gi\|199604981, gi... - gi\|200387883\|ref\|ZP_03214495.1\| cation-efflux pump FieF [Salmonella enterica subsp. enterica serovar... FIEF_SALG2 - Cation-efflux pump FieF OS=Salmonella gallinarum (strain 287/91 / NCTC 13346) GN=fieF PE=3 SV=1 FIEF_SALEP - Cation-efflux pump FieF OS=Salmonella enteritidis PT4 (strain P125109) GN=fieF PE=3 SV=1 FIEF_SALPC - Cation-efflux pump FieF OS=Salmonella paratyphi C (strain RKS4594) GN=fieF PE=3 SV=1 FIEF_SALNS - Cation-efflux pump FieF OS=Salmonella newport (strain SL254) GN=fieF PE=3 SV=1 FIEF_SALHS - Cation-efflux pump FieF OS=Salmonella heidelberg (strain SL476) GN=fieF PE=3 SV=1 gi\|197242682, gi... - gi\|197264427\|ref\|ZP_03164501.1\| cation-efflux pump FieF [Salmonella enterica subsp. enterica serovar... FIEF_SALDC - Cation-efflux pump FieF OS=Salmonella dublin (strain CT_02021853) GN=fieF PE=3 SV=1 FIEF_SALTY - Cation-efflux pump FieF OS=Salmonella typhimurium GN=fieF PE=3 SV=1 gi\|167991632, gi... - gi\|205330053\|gb\|EDZ16817.1\| cation-efflux pump FieF [Salmonella enterica subsp. enterica serovar 4,[... gi\|168244186, gi... - gi\|205336832\|gb\|EDZ23596.1\| cation-efflux pump FieF [Salmonella enterica subsp. enterica serovar Hei... FIEF_SALTY - Cation-efflux pump FieF OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=fieF PE=3... gi\|168263038, gi... - gi\|205348242\|gb\|EDZ34873.1\| cation-efflux pump FieF [Salmonella enterica subsp. enterica serovar Had... gi\|195630181, gi... - gi\|195630181\|gb\|EDX48821.1\| cation-efflux pump FieF [Salmonella enterica subsp. enterica serovar New... FIEF_SALPB - Cation-efflux pump fieF OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=fieF PE=3 SV=1 gi\|205323661, gi... - gi\|205323661\|gb\|EDZ11500.1\| cation-efflux pump FieF [Salmonella enterica subsp. enterica serovar Sai... FIEF_SALTY - Cation-efflux pump fieF OS=Salmonella typhimurium GN=fieF PE=3 SV=1 FIEF_SALPB - Cation-efflux pump FieF OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=fieF PE=3 SV=1	235.0	[0..1]	[296..1]
CZCD_BACSU - Cadmium, cobalt and zinc/H(+)-K(+) antiporter OS=Bacillus subtilis (strain 168) GN=czcD PE=1 SV=1 gi\|221314921 - gi\|221314921\|ref\|ZP_03596726.1\| cation-efflux system membrane protein [Bacillus subtilis subsp. subt... gi\|221319843 - gi\|221319843\|ref\|ZP_03601137.1\| cation-efflux system membrane protein [Bacillus subtilis subsp. subt... gi\|221324123 - gi\|221324123\|ref\|ZP_03605417.1\| cation-efflux system membrane protein [Bacillus subtilis subsp. subt... CZCD_BACSU - Cadmium, cobalt and zinc/H(+)-K(+) antiporter OS=Bacillus subtilis GN=czcD PE=1 SV=1	233.0	[0..1]	[294..1]
FIEF_SALPA - Cation-efflux pump FieF OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=fieF PE=3 SV=1 FIEF_SALA4 - Cation-efflux pump FieF OS=Salmonella agona (strain SL483) GN=fieF PE=3 SV=1 FIEF_SALPA - Cation-efflux pump FieF OS=Salmonella paratyphi A GN=fieF PE=3 SV=1 FIEF_SALPK - Cation-efflux pump FieF OS=Salmonella paratyphi A (strain AKU_12601) GN=fieF PE=3 SV=1	233.0	[0..1]	[296..1]
gi\|238785693, gi... - gi\|77956875\|ref\|ZP_00820950.1\| COG1230: Co/Zn/Cd efflux system component [Yersinia bercovieri ATCC 4...	233.0	[0..7]	[295..10]

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Predicted Domain #1

Region A:
Residues: [1-300]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNQSYGRLVS RAAIAATAMA SLLLLIKIFA WWYTGSVSIL AALVDSLVDI GASLTNLLVV  60
   61 RYSLQPADDN HSFGHGKAES LAALAQSMFI SGSALFLFLT GIQHLISPTP MTDPGVGVIV 120
  121 TIVALICTII LVSFQRWVVR RTQSQAVRAD MLHYQSDVMM NGAILLALGL SWYGWHRADA 180
  181 LFALGIGIYI LYSALRMGYE AVQSLLDRAL PDEERQEIID IVTSWPGVSG AHDLRTRQSG 240
  241 PTRFIQIHLE MEDSLPLVQA HMVADQVEQA ILRRFPGSDV IIHQDPCSVV PREGKRSMLS 300
  301

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	62.69897
Match:	2qfiA
Description:	No description for 2qfiA was found.

Predicted functions:

Term	Confidence	Notes
cation transmembrane transporter activity	4.80415740186568	bayes_pls_golite062009
ion transmembrane transporter activity	4.7111088918389	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	4.31582321262476	bayes_pls_golite062009
cadmium ion transmembrane transporter activity	3.70168909103546	bayes_pls_golite062009
cation efflux transmembrane transporter activity	3.58605967664273	bayes_pls_golite062009
zinc efflux transmembrane transporter activity	3.58605967664273	bayes_pls_golite062009
zinc efflux active transmembrane transporter activity	3.58605967664273	bayes_pls_golite062009
ferrous iron transmembrane transporter activity	3.11977033026307	bayes_pls_golite062009
zinc ion transmembrane transporter activity	2.95515682622113	bayes_pls_golite062009
transporter activity	2.75060749825863	bayes_pls_golite062009
transmembrane transporter activity	2.61478776136804	bayes_pls_golite062009
substrate-specific transporter activity	2.49211952065411	bayes_pls_golite062009
transition metal ion transmembrane transporter activity	1.29284396884348	bayes_pls_golite062009
iron ion transmembrane transporter activity	1.28901626534199	bayes_pls_golite062009
efflux transmembrane transporter activity	1.25549862417229	bayes_pls_golite062009
metal ion transmembrane transporter activity	1.01332825422669	bayes_pls_golite062009
binding	0.80253540865533	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	0.4725448545847	bayes_pls_golite062009
cation channel activity	0.114605430567645	bayes_pls_golite062009
di-, tri-valent inorganic cation transmembrane transporter activity	0.0866732167896778	bayes_pls_golite062009
protein binding	0.0557829197821959	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: