YRC Public Data Repository - Protein Structure Prediction

Protein:	YEHW_ECOLI
Organism:	Escherichia coli
Length:	243 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YEHW_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|29377126, gi\|... - gi\|29377126\|ref\|NP_816280.1\| glycine betaine/L-proline ABC transporter, glycine betaine/L-proline-bi... gi\|227554134, gi... - gi\|227554134\|ref\|ZP_03984181.1\| glycine betaine/carnitine/choline ABC superfamily ATP binding casset... gi\|229305475, gi... - gi\|229549238\|ref\|ZP_04437963.1\| glycine betaine/carnitine/choline ABC superfamily ATP binding casset... gi\|238857201, gi... - gi\|238857201\|ref\|ZP_04647451.1\| glycine betaine/L-proline ABC transporter, glycine betaine/L-proline...	172.0	[0..2]	[234..43]
gi\|77409771, gi\|... - gi\|77409771\|ref\|ZP_00786425.1\| amino acid ABC transporter, permease protein [Streptococcus agalactia...	171.0	[0..3]	[237..48]
gi\|77161934, gi\|... - gi\|77412028\|ref\|ZP_00788356.1\| amino acid ABC transporter, permease protein [Streptococcus agalactia... gi\|77406685, gi\|... - gi\|77406685\|ref\|ZP_00783726.1\| amino acid ABC transporter, permease protein [Streptococcus agalactia... gi\|76563504, gi\|... - gi\|76788447\|ref\|YP_330414.1\| glycine betaine/proline ABC transporter, permease/substrate-binding pro...	170.0	[0..3]	[237..48]
gi\|22537935, gi\|... - gi\|22537935\|ref\|NP_688786.1\| amino acid ABC transporter, permease protein [Streptococcus agalactiae ... gi\|76585744, gi\|... - gi\|76798898\|ref\|ZP_00781104.1\| amino acid ABC transporter, permease protein [Streptococcus agalactia...	170.0	[0..3]	[237..48]
gi\|69245959, gi\|... - gi\|69245959\|ref\|ZP_00603731.1\| Binding-protein-dependent transport systems inner membrane component:... gi\|48825338 - ref\|ZP_00286594.1\| COG4176: ABC-type proline/glycine betaine transport system, permease component [E...	170.0	[0..3]	[234..48]
gi\|254997399 - gi\|254997399\|dbj\|BAH88000.1\| putative ABC transporter, proline/glycine betaine permease protein [Str... gi\|24379499, gi\|... - gi\|24379499\|ref\|NP_721454.1\| putative ABC transporter, proline/glycine betaine permease protein [Str...	169.0	[0..3]	[237..48]
gi\|25011877, gi\|... - gi\|25011877\|ref\|NP_736272.1\| hypothetical protein gbs1838 [Streptococcus agalactiae NEM316], gi\|2441... gi\|77160043, gi\|... - gi\|77413910\|ref\|ZP_00790086.1\| amino acid ABC transporter, permease protein [Streptococcus agalactia...	167.0	[0..3]	[237..48]
gi\|139473033, gi... - gi\|139473033\|ref\|YP_001127748.1\| putative glycine-betaine binding permease protein [Streptococcus py... gi\|50902624, gi\|... - gi\|50913550\|ref\|YP_059522.1\| glycine betaine transport system permease protein [Streptococcus pyogen...	167.0	[0..3]	[237..48]
gi\|94541299, gi\|... - gi\|94987791\|ref\|YP_595892.1\| glycine betaine transport system permease protein [Streptococcus pyogen...	167.0	[0..3]	[237..48]
gi\|150390667, gi... - gi\|77683645\|ref\|ZP_00799091.1\| Binding-protein-dependent transport systems inner membrane component ...	163.0	[0..24]	[243..76]

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Predicted Domain #1

Region A:
Residues: [1-243]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKMLRDPLFW LIALFVALIF WLPYSQPLFA ALFPQLPRPV YQQESFAALA LAHFWLVGIS  60
   61 SLFAVIIGTG AGIAVTRPWG AEFRPLVETI AAVGQTFPPV AVLAIAVPVI GFGLQPAIIA 120
  121 LILYGVLPVL QATLAGLGAI DASVTEVAKG MGMSRGQRVR KVELPLAAPV ILAGVRTSVI 180
  181 INIGTATIAS TVGASTLGTP IIIGLSGFNT AYVIQGALLV ALAAIIADRL FERLVQALSQ 240
  241 HAK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	12.09691
Match:	2onkC
Description:	No description for 2onkC was found.

Predicted functions:

Term	Confidence	Notes
substrate-specific transmembrane transporter activity	3.90877533326679	bayes_pls_golite062009
ion transmembrane transporter activity	3.04751896510563	bayes_pls_golite062009
transporter activity	2.92901170384371	bayes_pls_golite062009
transmembrane transporter activity	2.82231503501622	bayes_pls_golite062009
active transmembrane transporter activity	2.62912035749387	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	2.58567076459772	bayes_pls_golite062009
primary active transmembrane transporter activity	2.58112472232827	bayes_pls_golite062009
ATPase activity, coupled to movement of substances	2.57722913421807	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	2.57722913421807	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances	2.57687258170314	bayes_pls_golite062009
cation transmembrane transporter activity	2.28111291142378	bayes_pls_golite062009
ATPase activity, coupled	2.26533438516544	bayes_pls_golite062009
ATPase activity	2.12523930663356	bayes_pls_golite062009
substrate-specific transporter activity	2.08705004234574	bayes_pls_golite062009
nucleoside-triphosphatase activity	2.06571106810861	bayes_pls_golite062009
pyrophosphatase activity	2.02843508794757	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	2.01869168199434	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	2.01800287925825	bayes_pls_golite062009
hydrolase activity	1.27489880499396	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions	0.86861612741394	bayes_pls_golite062009
catalytic activity	0.79821499476005	bayes_pls_golite062009
anion transmembrane-transporting ATPase activity	0.689648105332081	bayes_pls_golite062009
inorganic anion transmembrane transporter activity	0.67740655647842	bayes_pls_golite062009
carbohydrate transmembrane transporter activity	0.56369901852468	bayes_pls_golite062009
amine transmembrane transporter activity	0.525383483850367	bayes_pls_golite062009
anion transmembrane transporter activity	0.52374242151885	bayes_pls_golite062009
sugar transmembrane transporter activity	0.44915416750675	bayes_pls_golite062009
amino acid transmembrane transporter activity	0.110419368036337	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: