YRC Public Data Repository - Protein Structure Prediction

Protein:	YCHK_ECOLI
Organism:	Escherichia coli
Length:	314 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YCHK_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|209398050, gi... - gi\|209398050\|ref\|YP_002270165.1\| phospholipase, patatin family [Escherichia coli O157:H7 str. EC4115... gi\|15801462, gi\|... - gi\|15801462\|ref\|NP_287479.1\| hypothetical protein Z2010 [Escherichia coli O157:H7 EDL933], gi\|125149... gi\|215264542, gi... - gi\|215486470\|ref\|YP_002328901.1\| hypothetical protein E2348C_1361 [Escherichia coli O127:H6 str. E23... gi\|217328322, gi... - gi\|217328322\|ref\|ZP_03444404.1\| phospholipase, patatin family [Escherichia coli O157:H7 str. TW14588... gi\|218553786, gi... - gi\|218553786\|ref\|YP_002386699.1\| hypothetical protein ECIAI1_1254 [Escherichia coli IAI1], gi\|218360... gi\|189376317, gi... - gi\|189406130\|ref\|ZP_02826554.2\| phospholipase, patatin family [Escherichia coli O157:H7 str. EC508],... gi\|191170941, gi... - gi\|191170941\|ref\|ZP_03032492.1\| phospholipase, patatin family [Escherichia coli F11], gi\|190908673\|g... gi\|208733082, gi... - gi\|208816434\|ref\|ZP_03257613.1\| phospholipase, patatin family [Escherichia coli O157:H7 str. EC4045]... gi\|208822330, gi... - gi\|208822330\|ref\|ZP_03262649.1\| phospholipase, patatin family [Escherichia coli O157:H7 str. EC4042]... gi\|189402549, gi... - gi\|189402549\|ref\|ZP_02783166.2\| phospholipase, patatin family [Escherichia coli O157:H7 str. EC4401]... gi\|189403550, gi... - gi\|189403550\|ref\|ZP_02796130.2\| phospholipase, patatin family [Escherichia coli O157:H7 str. EC4486]... gi\|91072029, gi\|... - gi\|91210455\|ref\|YP_540441.1\| hypothetical protein UTI89_C1430 [Escherichia coli UTI89], gi\|91072029\|... gi\|189404428, gi... - gi\|189404428\|ref\|ZP_02789367.2\| phospholipase, patatin family [Escherichia coli O157:H7 str. EC4501]... gi\|13361201, gi\|... - gi\|15830990\|ref\|NP_309763.1\| hypothetical protein ECs1736 [Escherichia coli O157:H7 str. Sakai], gi\|... gi\|189404994, gi... - gi\|189404994\|ref\|ZP_02812745.2\| phospholipase, patatin family [Escherichia coli O157:H7 str. EC869],... gi\|170517641, gi... - gi\|170679923\|ref\|YP_001743961.1\| patatin family phospholipase [Escherichia coli SMS-3-5], gi\|1705176... gi\|187776332, gi... - gi\|187776332\|ref\|ZP_02801881.2\| phospholipase, patatin family [Escherichia coli O157:H7 str. EC4196]... gi\|188025065, gi... - gi\|188025065\|ref\|ZP_02775817.2\| phospholipase, patatin family [Escherichia coli O157:H7 str. EC4113]... gi\|188999994, gi... - gi\|189010486\|ref\|ZP_02807596.2\| phospholipase, patatin family [Escherichia coli O157:H7 str. EC4076]... gi\|209772340, gi... - pir\|\|H90845 hypothetical protein ECs1736 [imported] - Escherichia coli (strain O157:H7, substrain R... gi\|218364931, gi... - gi\|218558162\|ref\|YP_002391075.1\| hypothetical protein ECS88_1302 [Escherichia coli S88], gi\|21836493... gi\|227836542, gi... - gi\|227886338\|ref\|ZP_04004143.1\| alpha-beta hydrolase family esterase [Escherichia coli 83972], gi\|22... gi\|218689180, gi... - gi\|218689180\|ref\|YP_002397392.1\| hypothetical protein ECED1_1385 [Escherichia coli ED1a], gi\|2184267... gi\|226899954, gi... - gi\|237705197\|ref\|ZP_04535678.1\| conserved hypothetical protein [Escherichia sp. 3_2_53FAA], gi\|22689... gi\|13361201, gi\|... - gi\|15830990\|ref\|NP_309763.1\| hypothetical protein ECs1736 [Escherichia coli O157:H7], gi\|13361201\|db... gi\|218369926, gi... - gi\|218699940\|ref\|YP_002407569.1\| hypothetical protein ECIAI39_1569 [Escherichia coli IAI39], gi\|2183... gi\|26247563, gi\|... - gi\|26247563\|ref\|NP_753603.1\| hypothetical protein c1698 [Escherichia coli CFT073], gi\|26107965\|gb\|AA... gi\|115512573, gi... - gi\|117623449\|ref\|YP_852362.1\| hypothetical protein APECO1_348 [Escherichia coli APEC O1], gi\|1155125...	256.0	[0..1]	[314..1]
gi\|82544315, gi\|... - gi\|82544315\|ref\|YP_408262.1\| hypothetical protein SBO_1835 [Shigella boydii Sb227], gi\|81245726\|gb\|A...	256.0	[0..1]	[314..1]
gi\|205339686, gi... - gi\|205339686\|gb\|EDZ26450.1\| phospholipase, patatin family [Salmonella enterica subsp. enterica serov... gi\|194450925, gi... - gi\|194450925\|ref\|YP_002045799.1\| hypothetical protein SeHA_C1944 [Salmonella enterica subsp. enteric... gi\|161363117, gi... - gi\|161613753\|ref\|YP_001587718.1\| hypothetical protein SPAB_01487 [Salmonella enterica subsp. enteric... gi\|205327536, gi... - gi\|205327536\|gb\|EDZ14300.1\| phospholipase, patatin family [Salmonella enterica subsp. enterica serov... gi\|56127579, gi\|... - gi\|56413322\|ref\|YP_150397.1\| hypothetical protein SPA1124 [Salmonella enterica subsp. enterica serov... gi\|16765098, gi\|... - gi\|16765098\|ref\|NP_460713.1\| hypothetical protein STM1754 [Salmonella typhimurium LT2], gi\|16420286\|... lcl\|NC_016856.1_... - [gene=ychK] [protein=hypothetical protein] [protein_id=YP_005237682.1] [location=complement(1860732.... gi\|200390353, gi... - gi\|200390353\|ref\|ZP_03216964.1\| phospholipase, patatin family [Salmonella enterica subsp. enterica s... gi\|197266035, gi... - gi\|197266035\|ref\|ZP_03166109.1\| phospholipase, patatin family [Salmonella enterica subsp. enterica s... gi\|197093724, gi... - gi\|197362247\|ref\|YP_002141884.1\| hypothetical protein SSPA1043 [Salmonella enterica subsp. enterica ...	249.0	[0..14]	[314..1]
gi\|62180319, gi\|... - gi\|62180319\|ref\|YP_216736.1\| hypothetical protein SC1749 [Salmonella enterica subsp. enterica serova... gi\|224583754, gi... - gi\|224583754\|ref\|YP_002637552.1\| hypothetical protein SPC_1975 [Salmonella enterica subsp. enterica ... gi\|206708539, gi... - gi\|207856736\|ref\|YP_002243387.1\| hypothetical protein SEN1282 [Salmonella enterica subsp. enterica s... gi\|205352575, gi... - gi\|205352575\|ref\|YP_002226376.1\| hypothetical protein SG1362 [Salmonella enterica subsp. enterica se... gi\|204323097, gi... - gi\|204927755\|ref\|ZP_03218956.1\| phospholipase, patatin family [Salmonella enterica subsp. enterica s... gi\|198242035, gi... - gi\|198242035\|ref\|YP_002215389.1\| phospholipase, patatin family [Salmonella enterica subsp. enterica ... gi\|197211215, gi... - gi\|197247512\|ref\|YP_002146274.1\| phospholipase, patatin family [Salmonella enterica subsp. enterica ... gi\|194736874, gi... - gi\|194736874\|ref\|YP_002114785.1\| phospholipase, patatin family [Salmonella enterica subsp. enterica ... gi\|194470482, gi... - gi\|194470482\|ref\|ZP_03076466.1\| phospholipase, patatin family [Salmonella enterica subsp. enterica s... gi\|194402117, gi... - gi\|194443454\|ref\|YP_002041006.1\| phospholipase, patatin family [Salmonella enterica subsp. enterica ... gi\|205343803, gi... - gi\|205343803\|gb\|EDZ30567.1\| phospholipase, patatin family [Salmonella enterica subsp. enterica serov... gi\|168462770, gi... - gi\|195634017\|gb\|EDX52369.1\| phospholipase, patatin family [Salmonella enterica subsp. enterica serov... gi\|205351207, gi... - gi\|205351207\|gb\|EDZ37838.1\| phospholipase, patatin family [Salmonella enterica subsp. enterica serov... gi\|197289217, gi... - gi\|197289217\|gb\|EDY28584.1\| phospholipase, patatin family protein [Salmonella enterica subsp. enteri... gi\|167553689, gi... - gi\|205321919\|gb\|EDZ09758.1\| phospholipase, patatin family [Salmonella enterica subsp. enterica serov... gi\|238913656 - gi\|238913656\|ref\|ZP_04657493.1\| hypothetical protein SentesTe_21338 [Salmonella enterica subsp. ente...	248.0	[0..14]	[314..1]
gi\|16760129 - gi\|16760129\|ref\|NP_455746.1\| hypothetical protein STY1296 [Salmonella enterica subsp. enterica serov... gi\|213586988 - gi\|213586988\|ref\|ZP_03368814.1\| hypothetical protein SentesTyph_39181 [Salmonella enterica subsp. en... gi\|25358004, gi\|... - gi\|25358004\|pir\|\|AH0649 conserved hypothetical protein STY1296 [imported] - Salmonella enterica subs... gi\|213999233 - gi\|213999233\|ref\|ZP_03409968.1\| hypothetical protein Salmonellentericaenterica_00065 [Salmonella ent... gi\|29137729, gi\|... - gi\|29142100\|ref\|NP_805442.1\| hypothetical protein t1665 [Salmonella enterica subsp. enterica serovar... gi\|213650846 - gi\|213650846\|ref\|ZP_03380899.1\| hypothetical protein SentesTy_28633 [Salmonella enterica subsp. ente...	246.0	[0..14]	[314..1]
gi\|195939121 - gi\|195939121\|ref\|ZP_03084503.1\| hypothetical protein EscherichcoliO157_22327 [Escherichia coli O157:... gi\|208726073, gi... - gi\|208806272\|ref\|ZP_03248609.1\| phospholipase, patatin family [Escherichia coli O157:H7 str. EC4206]... gi\|209918475, gi... - gi\|209918475\|ref\|YP_002292559.1\| hypothetical protein ECSE_1284 [Escherichia coli SE11], gi\|20991173... gi\|218431852, gi... - gi\|218704755\|ref\|YP_002412274.1\| hypothetical protein ECUMN_1531 [Escherichia coli UMN026], gi\|21843... gi\|254592104, gi... - gi\|254792704\|ref\|YP_003077541.1\| hypothetical protein ECSP_1626 [Escherichia coli O157:H7 str. TW143... gi\|110641463, gi... - gi\|110641463\|ref\|YP_669193.1\| hypothetical protein ECP_1281 [Escherichia coli 536], gi\|110343055\|gb\|...	246.0	[0..14]	[314..1]
gi\|83569294, gi\|... - gi\|83569294\|ref\|ZP_00920750.1\| COG1752: Predicted esterase of the alpha-beta hydrolase superfamily [...	245.0	[0..14]	[314..1]
EG12120 - putative patatin-like family phospholipase / Predicted phospholipase, patatin-like family, function ... RSSA_SHIFL - NTE family protein RssA OS=Shigella flexneri GN=rssA PE=3 SV=2 gi\|124528384, gi... - gi\|124528384\|ref\|ZP_01699694.1\| Patatin [Escherichia coli B], gi\|124500616\|gb\|EAY48087.1\| Patatin [E... EG12120 - putative patatin-like family phospholipase / Predicted phospholipase, patatin-like family, function ... gi\|157160740, gi... - gi\|157160740\|ref\|YP_001458058.1\| hypothetical protein EcHS_A1342 [Escherichia coli HS], gi\|157066420... sp\|P0AFR0\|RSSA_ECOLI - NTE family protein rssA OS=Escherichia coli (strain K12) GN=rssA PE=1 SV=2 gi\|194424102, gi... - gi\|194437119\|ref\|ZP_03069218.1\| phospholipase, patatin family [Escherichia coli 101-1], gi\|194424102... gi\|30041002, gi\|... - gi\|30062754\|ref\|NP_836925.1\| hypothetical protein S1320 [Shigella flexneri 2a str. 2457T], gi\|300410... gi\|110614785, gi... - gi\|110805237\|ref\|YP_688757.1\| hypothetical protein SFV_1247 [Shigella flexneri 5 str. 8401], gi\|1106... gi\|56479861, gi\|... - gi\|56479861\|ref\|NP_707140.2\| hypothetical protein SF1234 [Shigella flexneri 2a str. 301], gi\|5638341...	245.0	[0..14]	[314..1]
gi\|77957070 - gi\|77957070\|ref\|ZP_00821136.1\| COG1752: Predicted esterase of the alpha-beta hydrolase superfamily [...	244.0	[0..14]	[311..1]
gi\|91714778, gi\|... - gi\|91792776\|ref\|YP_562427.1\| patatin [Shewanella denitrificans OS217], gi\|91714778\|gb\|ABE54704.1\| Pa...	243.0	[0..12]	[311..13]

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Predicted Domain #1

Region A:
Residues: [1-314]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATIAFQGNL AGIMRKIKIG LALGSGAARG WSHIGVINAL KKVGIEIDIV AGCSIGSLVG  60
   61 AAYACDRLSA LEDWVTSFSY WDVLRLMDLS WQRGGLLRGE RVFNQYREIM PETEIENCSR 120
  121 RFAAVATNLS TGRELWFTEG DLHLAIRASC SIPGLMAPVA HNGYWLVDGA VVNPIPISLT 180
  181 RALGADIVIA VDLQHDAHLM QQDLLSFNVS EENSENGDSL PWHARLKERL GSITTRRAVT 240
  241 APTATEIMTT SIQVLENRLK RNRMAGDPPD ILIQPVCPQI STLDFHRAHA AIAAGQLAVE 300
  301 RKMDELLPLV RTNI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	19.522879
Match:	1oxwA
Description:	Patatin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
phospholipase A2 activity	1.98467451720607	bayes_pls_golite062009
phospholipase activity	1.80454369034948	bayes_pls_golite062009
catalytic activity	1.681309422157	bayes_pls_golite062009
lipase activity	1.58686349518315	bayes_pls_golite062009
fatty acid synthase activity	1.20394174397151	bayes_pls_golite062009
[acyl-carrier-protein] S-malonyltransferase activity	0.812816692540436	bayes_pls_golite062009
S-malonyltransferase activity	0.812816692540436	bayes_pls_golite062009
malonyltransferase activity	0.812816692540436	bayes_pls_golite062009
hydrolase activity	0.582505020700489	bayes_pls_golite062009
carboxylesterase activity	0.543259402611534	bayes_pls_golite062009
acyltransferase activity	0.350701756346828	bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups	0.295883900540457	bayes_pls_golite062009
S-acyltransferase activity	0.279710514295726	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	0.208678652576559	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: