YRC Public Data Repository - Protein Structure Prediction

Protein:	ENTS_ECOLI, YBDA...
Organism:	Escherichia coli
Length:	416 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ENTS_ECOLI, YBDA....

Description	E-value	Query Range	Subject Range
gi\|110827356, gi... - gi\|111615223\|ref\|ZP_01402289.1\| Sugar phosphate permease-like [Verminephrobacter eiseniae EF01-2], g...	181.0	[0..11]	[410..296]
gi\|218202668 - gi\|218202668\|gb\|EEC85095.1\| hypothetical protein OsI_32467 [Oryza sativa Indica Group] PHT44_ORYSJ - Probable anion transporter 4, chloroplastic OS=Oryza sativa subsp. japonica GN=PHT4;4 PE=2 SV=1	176.0	[0..13]	[394..179]
gi\|60467752, gi\|... - gi\|60467752\|gb\|EAL65769.1\| hypothetical protein DDB0191430 [Dictyostelium discoideum], gi\|29500764\|g... gi\|60467752, gi\|... - gi\|66810832\|ref\|XP_639123.1\| major facilitator superfamily transporter [Dictyostelium discoideum AX4...	163.0	[0..18]	[372..603]
gi\|67536615, gi\|... - gi\|67542336\|ref\|ZP_00420273.1\| General substrate transporter:Major facilitator superfamily [Burkhold...	163.0	[0..17]	[415..278]
gi\|50085380, gi\|... - gi\|50085380\|ref\|YP_046890.1\| proline/glycine betaine transporter [Acinetobacter sp. ADP1], gi\|495313...	163.0	[0..24]	[416..42]
gi\|17064976, gi\|... - gi\|21387197\|gb\|AAM48002.1\| putative Na+-dependent inorganic phosphate cotransporter [Arabidopsis tha...	162.0	[0..13]	[397..100]
gi\|68389434 - gi\|68389434\|ref\|XP_691920.1\| PREDICTED: similar to solute carrier family 17 (sodium-dependent inorga...	162.0	[0..13]	[397..141]
gi\|50120481, gi\|... - gi\|50120481\|ref\|YP_049648.1\| proline/glycine betaine transporter [Pectobacterium atrosepticum SCRI10...	161.0	[0..13]	[415..22]
gi\|78495751, gi\|... - gi\|78495751\|ref\|ZP_00847969.1\| Major facilitator superfamily MFS_1 [Rhodopseudomonas palustris BisB1...	160.0	[0..2]	[416..436]

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Predicted Domain #1

Region A:
Residues: [1-416]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNKQSWLLNL SLLKTHPAFR AVFLARFISI VSLGLLGVAV PVQIQMMTHS TWQVGLSVTL  60
   61 TGGAMFVGLM VGGVLADRYE RKKVILLARG TCGIGFIGLC LNALLPEPSL LAIYLLGLWD 120
  121 GFFASLGVTA LLAATPALVG RENLMQAGAI TMLTVRLGSV ISPMIGGLLL ATGGVAWNYG 180
  181 LAAAGTFITL LPLLSLPALP PPPQPREHPL KSLLAGFRFL LASPLVGGIA LLGGLLTMAS 240
  241 AVRVLYPALA DNWQMSAAQI GFLYAAIPLG AAIGALTSGK LAHSARPGLL MLLSTLGSFL 300
  301 AIGLFGLMPM WILGVVCLAL FGWLSAVSSL LQYTMLQTQT PEAMLGRING LWTAQNVTGD 360
  361 AIGAALLGGL GAMMTPVASA SASGFGLLII GVLLLLVLVE LRHFRQTPPQ VTASDS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	31.221849
Match:	1pw4A
Description:	Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transporter activity	2.54286095434601	bayes_pls_golite062009
transmembrane transporter activity	2.01247278444729	bayes_pls_golite062009
substrate-specific transporter activity	1.77039368764865	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	1.66673693200184	bayes_pls_golite062009
active transmembrane transporter activity	0.33203350453105	bayes_pls_golite062009
polyol transmembrane transporter activity	0.24475883286552	bayes_pls_golite062009
alcohol transmembrane transporter activity	0.24475883286552	bayes_pls_golite062009
glycerol transmembrane transporter activity	0.2309068592963	bayes_pls_golite062009
ion transmembrane transporter activity	0.18188709249385	bayes_pls_golite062009
binding	0.105551689569449	bayes_pls_golite062009
glycerol-3-phosphate transmembrane transporter activity	1.26964387230144E-4	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: