YRC Public Data Repository - Protein Structure Prediction

Protein:	XAPB_ECOLI
Organism:	Escherichia coli
Length:	418 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for XAPB_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|110827356, gi... - gi\|111615223\|ref\|ZP_01402289.1\| Sugar phosphate permease-like [Verminephrobacter eiseniae EF01-2], g...	177.0	[0..2]	[395..301]
gi\|67536615, gi\|... - gi\|67542336\|ref\|ZP_00420273.1\| General substrate transporter:Major facilitator superfamily [Burkhold...	167.0	[0..1]	[418..276]
gi\|78495751, gi\|... - gi\|78495751\|ref\|ZP_00847969.1\| Major facilitator superfamily MFS_1 [Rhodopseudomonas palustris BisB1...	154.0	[0..3]	[415..451]
gi\|49650092 - gi\|49650092\|emb\|CAG79818.1\| YALI0E21241p [Yarrowia lipolytica] gi\|49650092, gi\|... - gi\|50553624\|ref\|XP_504223.1\| YALI0E21241p [Yarrowia lipolytica], gi\|49650092\|emb\|CAG79818.1\| unnamed...	147.0	[0..4]	[413..140]
gi\|60470323, gi\|... - gi\|66816473\|ref\|XP_642246.1\| sugar transporter family protein [Dictyostelium discoideum AX4], gi\|604... gi\|60470323 - gi\|60470323\|gb\|EAL68303.1\| hypothetical protein DDB0205325 [Dictyostelium discoideum]	146.0	[0..5]	[396..183]
gi\|163862954, gi... - gi\|89207137\|ref\|ZP_01185684.1\| General substrate transporter:Major facilitator superfamily MFS_1 [Ba...	143.0	[0..2]	[406..23]
gi\|76809832, gi\|... - gi\|76809832\|ref\|YP_333000.1\| putative proline/betaine transporter [Burkholderia pseudomallei 1710b],...	143.0	[0..1]	[418..167]
gi\|29896668, gi\|... - gi\|30021115\|ref\|NP_832746.1\| proline/betaine transporter [Bacillus cereus ATCC 14579], gi\|29896668\|g...	143.0	[0..2]	[406..23]
gi\|195994730, gi... - gi\|196031979\|ref\|ZP_03099393.1\| major facilitator family transporter [Bacillus cereus W], gi\|1959947... gi\|190564728, gi... - gi\|190564728\|ref\|ZP_03017649.1\| major facilitator family transporter [Bacillus anthracis Tsiankovski... gi\|177650164, gi... - gi\|177650164\|ref\|ZP_02933165.1\| major facilitator family transporter [Bacillus anthracis str. A0174]... gi\|170129807, gi... - gi\|170704952\|ref\|ZP_02895417.1\| major facilitator family transporter [Bacillus anthracis str. A0389]... gi\|170670981, gi... - gi\|170684721\|ref\|ZP_02875946.1\| major facilitator family transporter [Bacillus anthracis str. A0465]... gi\|167637102, gi... - gi\|167637102\|ref\|ZP_02395382.1\| major facilitator family transporter [Bacillus anthracis str. A0193]... gi\|167532041, gi... - gi\|167631743\|ref\|ZP_02390070.1\| major facilitator family transporter [Bacillus anthracis str. A0442]... gi\|164715031, gi... - gi\|165868305\|ref\|ZP_02212965.1\| major facilitator family transporter [Bacillus anthracis str. A0488]... gi\|50083000, gi\|... - gi\|50196938\|ref\|YP_052630.1\| major facilitator family transporter [Bacillus anthracis str. 'Ames Anc... gi\|30257607, gi\|... - gi\|30262974\|ref\|NP_845351.1\| major facilitator family transporter [Bacillus anthracis str. Ames], gi... gi\|228915603, gi... - gi\|228915603\|ref\|ZP_04079190.1\| proline/betaine transporter [Bacillus thuringiensis serovar pulsiens... gi\|227007137, gi... - gi\|227814178\|ref\|YP_002814187.1\| major facilitator family transporter [Bacillus anthracis str. CDC 6... gi\|49479280, gi\|... - gi\|49479280\|ref\|YP_037081.1\| glycine betaine/L-proline ABC transporter, permease [Bacillus thuringie... gi\|225790576, gi... - gi\|225864981\|ref\|YP_002750359.1\| major facilitator family transporter [Bacillus cereus 03BB102], gi\|... gi\|49179740, gi\|... - gi\|49185813\|ref\|YP_029065.1\| major facilitator family transporter [Bacillus anthracis str. Sterne], ... gi\|254738028 - gi\|254738028\|ref\|ZP_05195731.1\| major facilitator family transporter [Bacillus anthracis str. Wester... gi\|254722974 - gi\|254722974\|ref\|ZP_05184762.1\| major facilitator family transporter [Bacillus anthracis str. A1055] gi\|254685565 - gi\|254685565\|ref\|ZP_05149424.1\| major facilitator family transporter [Bacillus anthracis str. CNEVA-... gi\|229264726, gi... - gi\|229600318\|ref\|YP_002867254.1\| major facilitator family transporter [Bacillus anthracis str. A0248... gi\|254760861 - gi\|254760861\|ref\|ZP_05212885.1\| major facilitator family transporter [Bacillus anthracis str. Austra... gi\|254752345 - gi\|254752345\|ref\|ZP_05204381.1\| major facilitator family transporter [Bacillus anthracis str. Vollum... gi\|254742799 - gi\|254742799\|ref\|ZP_05200484.1\| major facilitator family transporter [Bacillus anthracis str. Kruger... gi\|218904133, gi... - gi\|218904133\|ref\|YP_002451967.1\| major facilitator family transporter [Bacillus cereus AH820], gi\|21... gi\|196043031, gi... - gi\|196043031\|ref\|ZP_03110270.1\| major facilitator family transporter [Bacillus cereus 03BB108], gi\|1... gi\|196031066, gi... - gi\|196037796\|ref\|ZP_03105106.1\| major facilitator family transporter [Bacillus cereus NVH0597-99], g...	143.0	[0..2]	[406..23]
gi\|47568603, gi\|... - gi\|47568603\|ref\|ZP_00239301.1\| proline/betaine transporter [Bacillus cereus G9241], gi\|47554699\|gb\|E...	143.0	[0..2]	[406..23]

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Predicted Domain #1

Region A:
Residues: [1-418]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSIAMRLKVM SFLQYFIWGS WLVTLGSYMI NTLHFTGANV GMVYSSKGIA AIIMPGIMGI  60
   61 IADKWLRAER AYMLCHLVCA GVLFYAASVT DPDMMFWVML VNAMAFMPTI ALSNSVSYSC 120
  121 LAQAGLDPVT AFPPIRVFGT VGFIVAMWAV SLLHLELSSL QLYIASGASL LLSAYALTLP 180
  181 KIPVAEKKAT TSLASKLGLD AFVLFKNPRM AIFFLFAMML GAVLQITNVF GNPFLHDFAR 240
  241 NPEFADSFVV KYPSILLSVS QMAEVGFILT IPFFLKRFGI KTVMLMSMVA WTLRFGFFAY 300
  301 GDPSTTGFIL LLLSMIVYGC AFDFFNISGS VFVEQEVDSS IRASAQGLFM TMVNGVGAWV 360
  361 GSILSGMAVD YFSVDGVKDW QTIWLVFAGY ALFLAVIFFF GFKYNHDPEK IKHRAVTH

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	28.09691
Match:	1pw4A
Description:	Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transporter activity	4.09176719149278	bayes_pls_golite062009
substrate-specific transporter activity	3.59744164024479	bayes_pls_golite062009
transmembrane transporter activity	3.5865018981083	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	3.54194478414824	bayes_pls_golite062009
ion transmembrane transporter activity	2.21266150105753	bayes_pls_golite062009
cation transmembrane transporter activity	1.79369588808394	bayes_pls_golite062009
active transmembrane transporter activity	1.59419818573076	bayes_pls_golite062009
secondary active transmembrane transporter activity	1.22264637452409	bayes_pls_golite062009
polyol transmembrane transporter activity	0.924836669821548	bayes_pls_golite062009
alcohol transmembrane transporter activity	0.924836669821548	bayes_pls_golite062009
glycerol transmembrane transporter activity	0.812001619402678	bayes_pls_golite062009
binding	0.805286077372817	bayes_pls_golite062009
symporter activity	0.74591237387473	bayes_pls_golite062009
solute:cation symporter activity	0.74591237387473	bayes_pls_golite062009
sugar:hydrogen symporter activity	0.143419068761182	bayes_pls_golite062009
cation:sugar symporter activity	0.143419068761182	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: