YRC Public Data Repository - Protein Structure Prediction

Protein:	SUFS_ECOLI
Organism:	Escherichia coli
Length:	406 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SUFS_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|89200187, gi\|... - gi\|89200187\|ref\|ZP_01178942.1\| Cysteine desulphurases, SufS [Bacillus cereus subsp. cytotoxis NVH 39...	395.0	[0..4]	[405..2]
gi\|218900136, gi... - gi\|218900136\|ref\|YP_002448547.1\| cysteine desulfurase SufS [Bacillus cereus G9842], gi\|218542809\|gb\|... gi\|228910821, gi... - gi\|228910821\|ref\|ZP_04074630.1\| cysteine desulfurase [Bacillus thuringiensis IBL 200], gi\|228848772\|... gi\|228856171, gi... - gi\|228903486\|ref\|ZP_04067611.1\| cysteine desulfurase [Bacillus thuringiensis IBL 4222], gi\|228856171... gi\|228961227, gi... - gi\|228961227\|ref\|ZP_04122847.1\| cysteine desulfurase [Bacillus thuringiensis serovar pakistani str. ... gi\|218233850, gi... - gi\|218233850\|ref\|YP_002369783.1\| cysteine desulfurase SufS [Bacillus cereus B4264], gi\|218161807\|gb\|... gi\|228817483, gi... - gi\|228942149\|ref\|ZP_04104689.1\| cysteine desulfurase [Bacillus thuringiensis serovar berliner ATCC 1... gi\|228784599, gi... - gi\|228975078\|ref\|ZP_04135637.1\| cysteine desulfurase [Bacillus thuringiensis serovar thuringiensis s... gi\|228968099, gi... - gi\|228968099\|ref\|ZP_04129104.1\| cysteine desulfurase [Bacillus thuringiensis serovar sotto str. T040... gi\|229032620, gi... - gi\|229032620\|ref\|ZP_04188584.1\| cysteine desulfurase [Bacillus cereus AH1271], gi\|228728705\|gb\|EEL79... gi\|228981718, gi... - gi\|228981718\|ref\|ZP_04142013.1\| cysteine desulfurase [Bacillus thuringiensis Bt407], gi\|228777830\|gb... gi\|229112426, gi... - gi\|229112426\|ref\|ZP_04241964.1\| cysteine desulfurase [Bacillus cereus Rock1-15], gi\|228671074\|gb\|EEL... gi\|229049673, gi... - gi\|229049673\|ref\|ZP_04194230.1\| cysteine desulfurase [Bacillus cereus AH676], gi\|228722586\|gb\|EEL739... gi\|74491798, gi\|... - gi\|75760714\|ref\|ZP_00740738.1\| Cysteine desulfurase / Selenocysteine lyase [Bacillus thuringiensis ... gi\|228630272, gi... - gi\|229153173\|ref\|ZP_04281352.1\| cysteine desulfurase [Bacillus cereus m1550], gi\|228630272\|gb\|EEK869... gi\|30023021, gi\|... - gi\|30023021\|ref\|NP_834652.1\| cysteine desulfhydrase [Bacillus cereus ATCC 14579], gi\|29898581\|gb\|AAP... gi\|229130239, gi... - gi\|229130239\|ref\|ZP_04259198.1\| cysteine desulfurase [Bacillus cereus BDRD-Cer4], gi\|228653172\|gb\|EE... gi\|228619580, gi... - gi\|229163959\|ref\|ZP_04291899.1\| cysteine desulfurase [Bacillus cereus R309803], gi\|228619580\|gb\|EEK7...	392.0	[0..4]	[405..2]
gi\|47505669, gi\|... - gi\|47530521\|ref\|YP_021870.1\| aminotransferase, class V [Bacillus anthracis str. 'Ames Ancestor'], gi... gi\|30265020, gi\|... - gi\|30265020\|ref\|NP_847397.1\| aminotransferase, class V [Bacillus anthracis str. Ames], gi\|30259697\|g... gi\|65316972, gi\|... - gi\|65316972\|ref\|ZP_00389931.1\| COG0520: Selenocysteine lyase [Bacillus anthracis str. A2012], ref\|NP... gi\|229268065, gi... - gi\|229603657\|ref\|YP_002869222.1\| cysteine desulfurase SufS [Bacillus anthracis str. A0248], gi\|22926...	392.0	[0..4]	[405..2]
gi\|206745313, gi... - gi\|206976389\|ref\|ZP_03237296.1\| cysteine desulfurase SufS [Bacillus cereus H3081.97], gi\|206745313\|g... gi\|196044098, gi... - gi\|196044098\|ref\|ZP_03111335.1\| cysteine desulfurase SufS [Bacillus cereus 03BB108], gi\|196025434\|gb... gi\|49187839, gi\|... - gi\|49187839\|ref\|YP_031092.1\| aminotransferase, class V [Bacillus anthracis str. Sterne], gi\|49181766... gi\|52140552, gi\|... - gi\|52140552\|ref\|YP_086277.1\| aminotransferase, class V, cysteine desulfhydrase [Bacillus cereus E33L... gi\|225866952, gi... - gi\|225866952\|ref\|YP_002752330.1\| cysteine desulfurase SufS [Bacillus cereus 03BB102], gi\|225785964\|g... gi\|228596228, gi... - gi\|229187218\|ref\|ZP_04314363.1\| cysteine desulfurase [Bacillus cereus BGSC 6E1], gi\|228596228\|gb\|EEK... gi\|228771520, gi... - gi\|228988223\|ref\|ZP_04148320.1\| cysteine desulfurase [Bacillus thuringiensis serovar tochigiensis BG... gi\|228917608, gi... - gi\|228917608\|ref\|ZP_04081152.1\| cysteine desulfurase [Bacillus thuringiensis serovar pulsiensis BGSC... gi\|227817752, gi... - gi\|227817752\|ref\|YP_002817761.1\| cysteine desulfurase SufS [Bacillus anthracis str. CDC 684], gi\|227... gi\|254735350 - gi\|254735350\|ref\|ZP_05193058.1\| cysteine desulfurase SufS [Bacillus anthracis str. Western North Ame... gi\|254725325 - gi\|254725325\|ref\|ZP_05187108.1\| cysteine desulfurase SufS [Bacillus anthracis str. A1055] gi\|254687313 - gi\|254687313\|ref\|ZP_05151170.1\| cysteine desulfurase SufS [Bacillus anthracis str. CNEVA-9066] gi\|228584398, gi... - gi\|229199127\|ref\|ZP_04325810.1\| cysteine desulfurase [Bacillus cereus m1293], gi\|228584398\|gb\|EEK425... gi\|42784164, gi\|... - gi\|42784164\|ref\|NP_981411.1\| aminotransferase, class V [Bacillus cereus ATCC 10987], gi\|42740095\|gb\|... gi\|254761463 - gi\|254761463\|ref\|ZP_05213484.1\| cysteine desulfurase SufS [Bacillus anthracis str. Australia 94] gi\|254753121 - gi\|254753121\|ref\|ZP_05205157.1\| cysteine desulfurase SufS [Bacillus anthracis str. Vollum] gi\|254740617 - gi\|254740617\|ref\|ZP_05198308.1\| cysteine desulfurase SufS [Bacillus anthracis str. Kruger B] gi\|118480065, gi... - gi\|118480065\|ref\|YP_897216.1\| cysteine desulfurase, aminotransferase class-V [Bacillus thuringiensis... gi\|190567163, gi... - gi\|190567163\|ref\|ZP_03020078.1\| cysteine desulfurase SufS [Bacillus anthracis Tsiankovskii-I], gi\|19... gi\|172082212, gi... - gi\|177652206\|ref\|ZP_02934709.1\| cysteine desulfurase SufS [Bacillus anthracis str. A0174], gi\|172082... gi\|170706965, gi... - gi\|170706965\|ref\|ZP_02897422.1\| cysteine desulfurase SufS [Bacillus anthracis str. A0389], gi\|170128... gi\|170686006, gi... - gi\|170686006\|ref\|ZP_02877229.1\| cysteine desulfurase SufS [Bacillus anthracis str. A0465], gi\|170670... gi\|167512122, gi... - gi\|167640041\|ref\|ZP_02398309.1\| cysteine desulfurase SufS [Bacillus anthracis str. A0193], gi\|167512... gi\|167529747, gi... - gi\|167634997\|ref\|ZP_02393315.1\| cysteine desulfurase SufS [Bacillus anthracis str. A0442], gi\|167529... gi\|164713435, gi... - gi\|165870926\|ref\|ZP_02215578.1\| cysteine desulfurase SufS [Bacillus anthracis str. A0488], gi\|164713...	391.0	[0..4]	[405..2]
gi\|42519066, gi\|... - gi\|42519066\|ref\|NP_964996.1\| selenocysteine lyase [Lactobacillus johnsonii NCC 533], gi\|41583353\|gb\|... gi\|31076070 - gi\|31076070\|emb\|CAD68973.1\| selenocysteine lyase [Lactobacillus johnsonii]	391.0	[0..1]	[405..1]
gi\|218906174, gi... - gi\|218906174\|ref\|YP_002454008.1\| cysteine desulfurase SufS [Bacillus cereus AH820], gi\|218535531\|gb\|... gi\|49332595, gi\|... - gi\|49481039\|ref\|YP_039000.1\| aminotransferase, class V; cysteine desulfhydrase [Bacillus thuringiens... gi\|47556336, gi\|... - gi\|47567018\|ref\|ZP_00237735.1\| MW0797 [Bacillus cereus G9241], gi\|47556336\|gb\|EAL14670.1\| MW0797 [Ba... gi\|195994370, gi... - gi\|196032941\|ref\|ZP_03100354.1\| cysteine desulfurase SufS [Bacillus cereus W], gi\|195994370\|gb\|EDX58... gi\|228823394, gi... - gi\|228936278\|ref\|ZP_04099077.1\| cysteine desulfurase [Bacillus thuringiensis serovar andalousiensis ... gi\|228930004, gi... - gi\|228930004\|ref\|ZP_04093015.1\| cysteine desulfurase [Bacillus thuringiensis serovar pondicheriensis... gi\|228658856, gi... - gi\|229124516\|ref\|ZP_04253701.1\| cysteine desulfurase [Bacillus cereus 95/8201], gi\|228658856\|gb\|EEL1... gi\|228948706, gi... - gi\|228948706\|ref\|ZP_04110984.1\| cysteine desulfurase [Bacillus thuringiensis serovar monterrey BGSC ... gi\|228590239, gi... - gi\|229193262\|ref\|ZP_04320213.1\| cysteine desulfurase [Bacillus cereus ATCC 10876], gi\|228590239\|gb\|E... gi\|228607819, gi... - gi\|229175678\|ref\|ZP_04303186.1\| cysteine desulfurase [Bacillus cereus MM3], gi\|228607819\|gb\|EEK65133...	390.0	[0..4]	[405..2]
gi\|20517684, gi\|... - gi\|20809014\|ref\|NP_624185.1\| selenocysteine lyase [Thermoanaerobacter tengcongensis MB4], gi\|2051768... gi\|20809014 - gi\|20809014\|ref\|NP_624185.1\| Selenocysteine lyase [Thermoanaerobacter tengcongensis MB4]	389.0	[0..2]	[405..1]
gi\|90436004, gi\|... - gi\|90588362\|ref\|ZP_01244014.1\| Cysteine desulphurases, SufS [Flavobacterium johnsoniae UW101], gi\|90...	388.0	[0..2]	[405..1]
gi\|229062649, gi... - gi\|229062649\|ref\|ZP_04199958.1\| cysteine desulfurase [Bacillus cereus AH603], gi\|228716619\|gb\|EEL683... gi\|228747124, gi... - gi\|229014170\|ref\|ZP_04171291.1\| cysteine desulfurase [Bacillus mycoides DSM 2048], gi\|228747124\|gb\|E... gi\|229169703, gi... - gi\|229169703\|ref\|ZP_04297403.1\| cysteine desulfurase [Bacillus cereus AH621], gi\|228613742\|gb\|EEK708... gi\|228647675, gi... - gi\|229135809\|ref\|ZP_04264579.1\| cysteine desulfurase [Bacillus cereus BDRD-ST196], gi\|228647675\|gb\|E... gi\|163864893, gi... - gi\|89206044\|ref\|ZP_01184607.1\| Cysteine desulphurases, SufS [Bacillus weihenstephanensis KBAB4], gi\|...	388.0	[0..4]	[405..2]
CSD_BACSU - Probable cysteine desulfurase OS=Bacillus subtilis GN=csd PE=3 SV=1 gi\|221324740 - gi\|221324740\|ref\|ZP_03606034.1\| cysteine desulfurase [Bacillus subtilis subsp. subtilis str. SMY] gi\|221315541 - gi\|221315541\|ref\|ZP_03597346.1\| cysteine desulfurase [Bacillus subtilis subsp. subtilis str. NCIB 36... gi\|221320456 - gi\|221320456\|ref\|ZP_03601750.1\| cysteine desulfurase [Bacillus subtilis subsp. subtilis str. JH642] SUFS_BACSU - Cysteine desulfurase SufS OS=Bacillus subtilis (strain 168) GN=sufS PE=1 SV=1	388.0	[0..4]	[405..2]

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Predicted Domain #1

Region A:
Residues: [1-406]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIFSVDKVRA DFPVLSREVN GLPLAYLDSA ASAQKPSQVI DAEAEFYRHG YAAVHRGIHT  60
   61 LSAQATEKME NVRKRASLFI NARSAEELVF VRGTTEGINL VANSWGNSNV RAGDNIIISQ 120
  121 MEHHANIVPW QMLCARVGAE LRVIPLNPDG TLQLETLPTL FDEKTRLLAI THVSNVLGTE 180
  181 NPLAEMITLA HQHGAKVLVD GAQAVMHHPV DVQALDCDFY VFSGHKLYGP TGIGILYVKE 240
  241 ALLQEMPPWE GGGSMIATVS LSEGTTWTKA PWRFEAGTPN TGGIIGLGAA LEYVSALGLN 300
  301 NIAEYEQNLM HYALSQLESV PDLTLYGPQN RLGVIAFNLG KHHAYDVGSF LDNYGIAVRT 360
  361 GHHCAMPLMA YYNVPAMCRA SLAMYNTHEE VDRLVTGLQR IHRLLG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	104.0
Match:	1jf9A
Description:	NifS-like protein/selenocysteine lyase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
glycine dehydrogenase (decarboxylating) activity	3.40354781002256	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor	3.40354781002256	bayes_pls_golite062009
transferase activity	2.59075614411581	bayes_pls_golite062009
catalytic activity	2.29878871754893	bayes_pls_golite062009
L-aspartate:2-oxoglutarate aminotransferase activity	1.62166853560902	bayes_pls_golite062009
cysteine desulfurase activity	1.30923778688541	bayes_pls_golite062009
transferase activity, transferring nitrogenous groups	1.28316822767388	bayes_pls_golite062009
transaminase activity	1.24990480711889	bayes_pls_golite062009
binding	0.942651665520336	bayes_pls_golite062009
carbon-sulfur lyase activity	0.698312655247044	bayes_pls_golite062009
5-aminolevulinate synthase activity	0.523223426448441	bayes_pls_golite062009
cystathionine gamma-lyase activity	0.505859361763689	bayes_pls_golite062009
transferase activity, transferring acyl groups	0.50269055590758	bayes_pls_golite062009
cystathionine beta-lyase activity	0.27933426619091	bayes_pls_golite062009
glycine hydroxymethyltransferase activity	0.271623203801431	bayes_pls_golite062009
O-phospho-L-serine:2-oxoglutarate aminotransferase activity	0.234399054481664	bayes_pls_golite062009
nucleic acid binding	0.186646089509162	bayes_pls_golite062009
vitamin B6 binding	0.16957228630576	bayes_pls_golite062009
pyridoxal phosphate binding	0.16957228630576	bayes_pls_golite062009
sulfurtransferase activity	0.0450490929307473	bayes_pls_golite062009
DNA binding	0.0281750086102144	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: