YRC Public Data Repository - Protein Structure Prediction

Protein:	RS12_AQUAE
Organism:	Aquifex aeolicus
Length:	128 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RS12_AQUAE.

Description	E-value	Query Range	Subject Range
gi\|71730663, gi\|... - gi\|71899534\|ref\|ZP_00681690.1\| Ribosomal protein S12, bacterial and chloroplast form [Xylella fastid...	207.0	[0..1]	[124..42]
gi\|92910094, gi\|... - gi\|92910094\|ref\|ZP_01278870.1\| Ribosomal protein S12 [Mycobacterium sp. JLS], gi\|92432182\|gb\|EAS9151... gi\|92438565, gi\|... - gi\|92917301\|ref\|ZP_01285915.1\| Ribosomal protein S12 [Mycobacterium sp. KMS], gi\|92438565\|gb\|EAS9641...	206.0	[0..1]	[124..135]
RS12_TRIEI - 30S ribosomal protein S12 OS=Trichodesmium erythraeum (strain IMS101) GN=rpsL PE=3 SV=1	206.0	[0..1]	[124..1]
gi\|56313632, gi\|... - gi\|56477589\|ref\|YP_159178.1\| 30S ribosomal protein S12 [Azoarcus sp. EbN1], gi\|56313632\|emb\|CAI08277...	205.0	[0..1]	[125..13]
gi\|33575063, gi\|... - gi\|33599017\|ref\|NP_886577.1\| 30S ribosomal protein S12 [Bordetella bronchiseptica RB50], gi\|33575063...	204.0	[0..1]	[125..22]
RS12_NOSP7 - 30S ribosomal protein S12 OS=Nostoc punctiforme (strain ATCC 29133 / PCC 73102) GN=rpsL PE=3 SV=1	204.0	[0..1]	[126..1]
gi\|79685 - gi\|79685\|pir\|\|S04427 ribosomal protein S12 - Synechococcus sp. (PCC 6301) RS12_SYNP6 - 30S ribosomal protein S12 OS=Synechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1) GN=rpsL ... RS12_SYNE7 - 30S ribosomal protein S12 OS=Synechococcus elongatus (strain PCC 7942) GN=rpsL PE=3 SV=1	204.0	[0..1]	[124..1]
gi\|74275829, gi\|... - gi\|75437463\|ref\|ZP_00733433.1\| 30S ribosomal protein S12 [Actinobacillus succinogenes 130Z], gi\|7427...	203.0	[0..1]	[124..19]
RS12_PROMM - 30S ribosomal protein S12 OS=Prochlorococcus marinus (strain MIT 9313) GN=rpsL PE=3 SV=1 RS12_PROM3 - 30S ribosomal protein S12 OS=Prochlorococcus marinus (strain MIT 9303) GN=rpsL PE=3 SV=1	203.0	[0..1]	[125..1]
RS12_CUPPJ - 30S ribosomal protein S12 OS=Cupriavidus pinatubonensis (strain JMP 134 / LMG 1197) GN=rpsL PE=3 SV=...	203.0	[0..1]	[125..1]

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Predicted Domain #1

Region A:
Residues: [1-128]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPTFNQLVKY GREKRKKKSK APALQGCPQK RGVCVRVYTV TPKKPNSALR KVARVRLSNG  60
   61 IEVTAYIPGE GHNLQEHSIV LVRGGRVKDL PGVRYKIIRG ALDAAGVEGR RQSRSKYGTK 120
  121 RPKEEKGG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	50.39794
Match:	1vs5L
Description:	No description for 1vs5L was found.

Predicted functions:

Term	Confidence	Notes
structural constituent of ribosome	7.45319063235379	bayes_pls_golite062009
structural molecule activity	6.87843523680097	bayes_pls_golite062009
misfolded RNA binding	4.4877915495248	bayes_pls_golite062009
nucleic acid binding	3.63363905192127	bayes_pls_golite062009
RNA binding	3.30183895019873	bayes_pls_golite062009
DNA binding	2.84579720873153	bayes_pls_golite062009
	2.80746531284205	bayes_pls_golite062009
binding	2.40532042551671	bayes_pls_golite062009
mRNA binding	1.65819015373151	bayes_pls_golite062009
translation regulator activity	1.46320772716954	bayes_pls_golite062009
translation factor activity, nucleic acid binding	1.40718318783582	bayes_pls_golite062009
translation initiation factor activity	1.27539679024898	bayes_pls_golite062009
protein binding	1.20309946451799	bayes_pls_golite062009
transcription regulator activity	1.1059706841002	bayes_pls_golite062009
structure-specific DNA binding	1.10289736160471	bayes_pls_golite062009
single-stranded DNA binding	0.96886436248958	bayes_pls_golite062009
transcription factor activity	0.540940243804807	bayes_pls_golite062009
ribonuclease activity	0.498439111185072	bayes_pls_golite062009
aminoacyl-tRNA ligase activity	0.474251377131502	bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds	0.47336621289748	bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds	0.47336621289748	bayes_pls_golite062009
transcription activator activity	0.458219339846021	bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters	0.438266295385131	bayes_pls_golite062009
exoribonuclease activity	0.39131721416336	bayes_pls_golite062009
sequence-specific DNA binding	0.23198185345804	bayes_pls_golite062009
nuclease activity	0.17660139576327	bayes_pls_golite062009
3'-5'-exoribonuclease activity	0.0717589400404304	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: