YRC Public Data Repository - Protein Structure Prediction

Protein:	PTSO_ECOLI
Organism:	Escherichia coli
Length:	90 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PTSO_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|20808237, gi\|... - gi\|20808237\|ref\|NP_623408.1\| phosphotransferase system, HPr-related proteins [Thermoanaerobacter ten... gi\|20808237 - gi\|20808237\|ref\|NP_623408.1\| Phosphotransferase system, HPr-related proteins [Thermoanaerobacter ten...	120.0	[0..2]	[90..1]
gi\|241885227, gi... - gi\|241902512\|ref\|ZP_04787246.1\| phosphocarrier, HPr family [Thermoanaerobacter brockii subsp. finni... gi\|76796564, gi\|... - gi\|76796564\|ref\|ZP_00778923.1\| Phosphoryl transfer system, HPr [Thermoanaerobacter ethanolicus ATCC ...	118.0	[0..2]	[90..1]
gi\|114804824, gi... - gi\|167039835\|ref\|YP_001662820.1\| phosphotransferase system, phosphocarrier protein HPr [Thermoanaero... gi\|242256248, gi... - gi\|242256248\|ref\|ZP_04801142.1\| phosphocarrier, HPr family [Thermoanaerobacter sp. X513], gi\|2422322...	118.0	[0..2]	[90..1]
gi\|74057926, gi\|... - gi\|74318431\|ref\|YP_316171.1\| HPrNtr [Thiobacillus denitrificans ATCC 25259], gi\|74057926\|gb\|AAZ98366...	117.0	[0..2]	[90..1]
gi\|91774503, gi\|... - gi\|91774503\|ref\|YP_544259.1\| HPrNtr [Methylobacillus flagellatus KT], gi\|91708490\|gb\|ABE48418.1\| HPr...	113.0	[0..2]	[89..1]
gi\|119865757, gi... - gi\|119947153\|ref\|YP_944833.1\| bifunctional fructose-specific PTS IIA/HPr protein [Psychromonas ingra...	111.0	[0..4]	[89..283]
gi\|94501790, gi\|... - gi\|94501790\|ref\|ZP_01308303.1\| probable phosphocarrier protein hpr (phosphohistidinoprotein-hexose p...	111.0	[0..2]	[90..5]
gi\|83746874, gi\|... - gi\|83746874\|ref\|ZP_00943921.1\| Phosphocarrier protein HPr [Ralstonia solanacearum UW551], gi\|8372645... gi\|206593580, gi... - gi\|207742192\|ref\|YP_002258584.1\| phosphocarrier protein hpr (phosphohistidinoprotein-hexose phosphot... gi\|207727789, gi... - gi\|207727789\|ref\|YP_002256183.1\| phosphocarrier protein hpr (phosphohistidinoprotein-hexose phosphot...	110.0	[0..2]	[89..1]
gi\|83652478, gi\|... - gi\|83718653\|ref\|YP_440970.1\| phosphocarrier protein HPr [Burkholderia thailandensis E264], gi\|836524... gi\|167617763 - gi\|167617763\|ref\|ZP_02386394.1\| phosphocarrier protein HPr [Burkholderia thailandensis Bt4] gi\|167579686 - gi\|167579686\|ref\|ZP_02372560.1\| phosphocarrier protein HPr [Burkholderia thailandensis TXDOH]	110.0	[0..2]	[89..1]
gi\|17427356 - gi\|17427356\|emb\|CAD13875.1\| probable phosphocarrier protein hpr (phosphohistidinoprotein-hexose phos... gi\|17545066 - gi\|17545066\|ref\|NP_518468.1\| phosphohistidinoprotein-hexose phosphotransferase [Ralstonia solanacear...	110.0	[0..2]	[89..1]

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Predicted Domain #1

Region A:
Residues: [1-90]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTVKQTVEIT NKLGMHARPA MKLFELMQGF DAEVLLRNDE GTEAEANSVI ALLMLDSAKG  60
   61 RQIEVEATGP QEEEALAAVI ALFNSGFDED

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	22.39794
Match:	1ggrB
Description:	Histidine-containing phosphocarrier protein (HPr)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
protein-N(PI)-phosphohistidine-sugar phosphotransferase activity	5.70778264466435	bayes_pls_golite062009
carbohydrate transmembrane transporter activity	4.7398246519874	bayes_pls_golite062009
transporter activity	1.94557075462337	bayes_pls_golite062009
transmembrane transporter activity	1.8285077384404	bayes_pls_golite062009
active transmembrane transporter activity	1.73790085561506	bayes_pls_golite062009
substrate-specific transporter activity	1.57976971135135	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	1.4723961195197	bayes_pls_golite062009
catalytic activity	1.16445344378552	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.97685688328333	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.61783246115451	bayes_pls_golite062009
binding	0.569728786489819	bayes_pls_golite062009
transferase activity	0.08533057053308	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: