YRC Public Data Repository - Protein Structure Prediction

Protein:	PTFX2_ECOLI, PT1...
Organism:	Escherichia coli
Length:	833 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PTFX2_ECOLI, PT1....

Description	E-value	Query Range	Subject Range
gi\|191168940, gi... - gi\|75227816\|ref\|ZP_00714534.1\| COG1080: Phosphoenolpyruvate-protein kinase (PTS system EI component ...	707.0	[0..1]	[833..1]
gi\|75513866, gi\|... - gi\|75513866\|ref\|ZP_00736219.1\| COG1080: Phosphoenolpyruvate-protein kinase (PTS system EI component ...	707.0	[0..1]	[833..1]
gi\|91075069, gi\|... - gi\|91213495\|ref\|YP_543481.1\| phosphoenolpyruvate-protein phosphotransferase ptsA [Escherichia coli U... gi\|226902922, gi... - gi\|237702985\|ref\|ZP_04533466.1\| phosphoenolpyruvate-protein phosphotransferase ptsA [Escherichia sp.... gi\|115515341, gi... - gi\|117626217\|ref\|YP_859540.1\| phosphoenolpyruvate-protein phosphotransferase PtsA [Escherichia coli ...	706.0	[0..1]	[833..1]
gi\|189367929, gi... - gi\|189367929\|gb\|EDU86345.1\| multi-phosphoryl transfer protein 2 [Escherichia coli O157:H7 str. EC450... gi\|189357213, gi... - gi\|189357213\|gb\|EDU75632.1\| multi-phosphoryl transfer protein 2 [Escherichia coli O157:H7 str. EC440... gi\|168748746, gi... - gi\|188016825\|gb\|EDU54947.1\| multi-phosphoryl transfer protein 2 [Escherichia coli O157:H7 str. EC411... gi\|38704216 - gi\|38704216\|ref\|NP_312903.2\| PEP-protein phosphotransferase system enzyme I [Escherichia coli O157:H... gi\|254595353, gi... - gi\|254795953\|ref\|YP_003080790.1\| fused predicted PTS enzymes: Hpr component, enzyme I component, enz... gi\|38704216 - gi\|38704216\|ref\|NP_312903.2\| PEP-protein phosphotransferase system enzyme I [Escherichia coli O157:H... gi\|217325451, gi... - gi\|217325451\|ref\|ZP_03441535.1\| multi-phosphoryl transfer protein 2 [Escherichia coli O157:H7 str. T... gi\|209161274, gi... - gi\|209399874\|ref\|YP_002273470.1\| multi-phosphoryl transfer protein 2 [Escherichia coli O157:H7 str. ... gi\|208739137, gi... - gi\|208819014\|ref\|ZP_03259334.1\| multi-phosphoryl transfer protein 2 [Escherichia coli O157:H7 str. E... gi\|208812735, gi... - gi\|208812735\|ref\|ZP_03254064.1\| multi-phosphoryl transfer protein 2 [Escherichia coli O157:H7 str. E... gi\|208727005, gi... - gi\|208807204\|ref\|ZP_03249541.1\| multi-phosphoryl transfer protein 2 [Escherichia coli O157:H7 str. E... gi\|195937598 - gi\|195937598\|ref\|ZP_03082980.1\| PEP-protein phosphotransferase system enzyme I [Escherichia coli O15... gi\|189378097, gi... - gi\|189378097\|gb\|EDU96513.1\| multi-phosphoryl transfer protein 2 [Escherichia coli O157:H7 str. EC508... gi\|189001574, gi... - gi\|189001574\|gb\|EDU70560.1\| multi-phosphoryl transfer protein 2 [Escherichia coli O157:H7 str. EC407... gi\|168775208, gi... - gi\|187769129\|gb\|EDU32973.1\| multi-phosphoryl transfer protein 2 [Escherichia coli O157:H7 str. EC419... gi\|168768260, gi... - gi\|189362597\|gb\|EDU81016.1\| multi-phosphoryl transfer protein 2 [Escherichia coli O157:H7 str. EC448...	706.0	[0..1]	[833..1]
gi\|157156963, gi... - gi\|75188685\|ref\|ZP_00701952.1\| COG1080: Phosphoenolpyruvate-protein kinase (PTS system EI component ... gi\|218556509, gi... - gi\|218556509\|ref\|YP_002389423.1\| fused putative PTS enzymes: Hpr component ; enzyme I component ; en... gi\|192929402, gi... - gi\|75258068\|ref\|ZP_00729529.1\| COG1080: Phosphoenolpyruvate-protein kinase (PTS system EI component ... gi\|194429418, gi... - gi\|75209366\|ref\|ZP_00709602.1\| COG1080: Phosphoenolpyruvate-protein kinase (PTS system EI component ...	706.0	[0..1]	[833..1]
gi\|227837681, gi... - gi\|227885305\|ref\|ZP_04003110.1\| phosphoenolpyruvate-protein phosphotransferase ptsA [Escherichia col... gi\|26111151, gi\|... - gi\|26250720\|ref\|NP_756760.1\| phosphoenolpyruvate-protein phosphotransferase ptsA [Escherichia coli C...	706.0	[0..1]	[833..1]
gi\|16422678, gi\|... - gi\|16767376\|ref\|NP_462991.1\| PEP-protein phosphotransferase [Salmonella typhimurium LT2], gi\|1642267... lcl\|NC_016856.1_... - [gene=ptsA] [protein=PEP-protein phosphotransferase] [protein_id=YP_005240394.1] [location=complemen...	705.0	[0..1]	[833..1]
gi\|62182572, gi\|... - gi\|62182572\|ref\|YP_218989.1\| general PTS family protein I [Salmonella enterica subsp. enterica serov...	705.0	[0..1]	[833..1]
gi\|110644288, gi... - gi\|110644288\|ref\|YP_672018.1\| phosphoenolpyruvate-protein phosphotransferase PtsA [Escherichia coli ... gi\|190906980, gi... - gi\|75240345\|ref\|ZP_00724285.1\| COG1080: Phosphoenolpyruvate-protein kinase (PTS system EI component ...	705.0	[0..1]	[833..1]
gi\|253975799, gi... - gi\|254163898\|ref\|YP_003047006.1\| fused predicted PTS enzymes: Hpr component/enzyme I component/enzym... gi\|253326457, gi... - gi\|254290649\|ref\|YP_003056397.1\| fused predicted PTS enzymes: Hpr component/enzyme I component/enzym... gi\|157163425, gi... - gi\|75197821\|ref\|ZP_00707891.1\| COG1080: Phosphoenolpyruvate-protein kinase (PTS system EI component ... gi\|194422743, gi... - gi\|83586208\|ref\|ZP_00924844.1\| COG1080: Phosphoenolpyruvate-protein kinase (PTS system EI component ... gi\|251787211, gi... - gi\|251787211\|ref\|YP_003001515.1\| hypothetical protein B21_03782 [Escherichia coli BL21], gi\|24237948...	704.0	[0..1]	[833..1]

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Predicted Domain #1

Region A:
Residues: [1-99]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALIVEFICE LPNGVHARPA SHVETLCNTF SSQIEWHNLR TDRKGNAKSA LALIGTDTLA  60
   61 GDNCQLLISG ADEQEAHQRL SQWLRDEFPH CDAPLAEVK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	15.0
Match:	1ggrB
Description:	Histidine-containing phosphocarrier protein (HPr)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
protein-N(PI)-phosphohistidine-sugar phosphotransferase activity	5.70778264466435	bayes_pls_golite062009
carbohydrate transmembrane transporter activity	4.7398246519874	bayes_pls_golite062009
transporter activity	1.94557075462337	bayes_pls_golite062009
transmembrane transporter activity	1.8285077384404	bayes_pls_golite062009
active transmembrane transporter activity	1.73790085561506	bayes_pls_golite062009
substrate-specific transporter activity	1.57976971135135	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	1.4723961195197	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.97685688328333	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.61783246115451	bayes_pls_golite062009
binding	0.569728786489819	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [100-678]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SDELEPLPVS LTNLNPQIIR ARTVCSGSAG GILTPISSLD LNALGNLPAA KGVDAEQSAL  60
   61 ENGLTLVLKN IEFRLLDSDG ATSAILEAHR SLAGDTSLRE HLLAGVSAGL SCAEAIVASA 120
  121 NHFCEEFSRS SSSYLQERAL DVRDVCFQLL QQIYGEQRFP APGKLTQPAI CMADELTPSQ 180
  181 FLELDKNHLK GLLLKSGGTT SHTVILARSF NIPTLVGVDI DALTPWQQQT IYIDGNAGAI 240
  241 VVEPGEAVAR YYQQEARVQD ALREQQRVWL TQQARTADGI RIEIAANIAH SVEAQAAFGN 300
  301 GAEGVGLFRT EMLYMDRTSA PGESELYNIF CQALESANGR SIIVRTMDIG GDKPVDYLNI 360
  361 PAEANPFLGY RAVRIYEEYA SLFTTQLRSI LRASAHGSLK IMIPMISSME EILWVKEKLA 420
  421 EAKQQLRNEH IPFDEKIQLG IMLEVPSVMF IIDQCCEEID FFSIGSNDLT QYLLAVDRDN 480
  481 AKVTRHYNSL NPAFLRALDY AVQAVHRQGK WIGLCGELGA KGSVLPLLVG LGLDELSMSA 540
  541 PSIPAAKARM AQLDSRECRK LLNQAMACRT SLEVEHLLA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	169.0
Match:	2hroA
Description:	No description for 2hroA was found.

Predicted Domain #3

Region A:
Residues: [679-833]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QFRMTQQDAP LVTAECITLE SDWRSKEEVL KGMTDNLLLA GRCRYPRKLE ADLWAREAVF  60
   61 STGLGFSFAI PHSKSEHIEQ STISVARLQA PVRWGDDEAQ FIIMLTLNKH AAGDQHMRIF 120
  121 SRLARRIMHE EFRNALVNAA SADAIASLLQ HELEL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	28.69897
Match:	2a0jA
Description:	Crystal Structure of Nitrogen Regulatory Protein IIA-Ntr from Neisseria meningitidis
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: