YRC Public Data Repository - Protein Structure Prediction

Protein:	PEPT_ECOLI
Organism:	Escherichia coli
Length:	408 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PEPT_ECOLI.

Description	E-value	Query Range	Subject Range
PEPT_GEOKA - Peptidase T OS=Geobacillus kaustophilus (strain HTA426) GN=pepT PE=3 SV=1 PEPT_GEOKA - Peptidase T OS=Geobacillus kaustophilus GN=pepT PE=3 SV=1	321.0	[0..2]	[407..3]
gi\|114804728, gi... - gi\|167039851\|ref\|YP_001662836.1\| peptidase T [Thermoanaerobacter sp. X514], gi\|166854091\|gb\|ABY92500... gi\|242232221, gi... - gi\|242256266\|ref\|ZP_04801160.1\| peptidase T [Thermoanaerobacter sp. X513], gi\|242232221\|gb\|EES34538....	318.0	[0..1]	[407..7]
gi\|76588081, gi\|... - gi\|76796577\|ref\|ZP_00778936.1\| Peptidase M20B , tripeptide aminopeptidase [Thermoanaerobacter ethano...	316.0	[0..1]	[407..7]
PEPT_CALS4 - Peptidase T OS=Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NB... PEPT_THETN - Peptidase T OS=Thermoanaerobacter tengcongensis GN=pepT PE=3 SV=1	316.0	[0..1]	[407..1]
gi\|75255669 - gi\|75255669\|ref\|ZP_00727441.1\| COG2195: Di- and tripeptidases [Escherichia coli E22]	315.0	[0..1]	[408..1]
gi\|75209207, gi\|... - gi\|75209207\|ref\|ZP_00709454.1\| COG2195: Di- and tripeptidases [Escherichia coli B171], gi\|194429541\|... gi\|195182814 - gi\|195182814\|dbj\|BAG66390.1\| peptidase T [Escherichia coli O111:H-]	314.0	[0..1]	[408..1]
gi\|26107749, gi\|... - gi\|26247348\|ref\|NP_753388.1\| peptidase T [Escherichia coli CFT073], gi\|26107749\|gb\|AAN79948.1\|AE0167...	314.0	[0..1]	[408..16]
gi\|75228461 - gi\|75228461\|ref\|ZP_00715101.1\| COG2195: Di- and tripeptidases [Escherichia coli B7A]	314.0	[0..1]	[408..1]
PEPT_ECOSE - Peptidase T OS=Escherichia coli (strain SE11) GN=pepT PE=3 SV=1 gi\|193071464, gi... - gi\|75214988\|ref\|ZP_00713453.1\| COG2195: Di- and tripeptidases [Escherichia coli E110019], gi\|1930714...	313.0	[0..1]	[408..1]
PEPT_ECO24 - Peptidase T OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=pepT PE=3 SV=1	313.0	[0..1]	[408..1]

Back

Predicted Domain #1

Region A:
Residues: [1-408]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDKLLERFLN YVSLDTQSKA GVRQVPSTEG QWKLLHLLKE QLEEMGLINV TLSEKGTLMA  60
   61 TLPANVPGDI PAIGFISHVD TSPDCSGKNV NPQIVENYRG GDIALGIGDE VLSPVMFPVL 120
  121 HQLLGQTLIT TDGKTLLGAD DKAGIAEIMT ALAVLQQKKI PHGDIRVAFT PDEEVGKGAK 180
  181 HFDVDAFDAR WAYTVDGGGV GELEFENFNA ASVNIKIVGN NVHPGTAKGV MVNALSLAAR 240
  241 IHAEVPADES PEMTEGYEGF YHLASMKGTV ERADMHYIIR DFDRKQFEAR KRKMMEIAKK 300
  301 VGKGLHPDCY IELVIEDSYY NMREKVVEHP HILDIAQQAM RDCDIEPELK PIRGGTDGAQ 360
  361 LSFMGLPCPN LFTGGYNYHG KHEFVTLEGM EKAVQVIVRI AELTAQRK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	84.39794
Match:	1vixA
Description:	Crystal structure of a putative peptidase T
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hydrolase activity	3.17104798571343	bayes_pls_golite062009
peptidase activity	2.99879418448481	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	2.36949934818383	bayes_pls_golite062009
catalytic activity	2.00064748759729	bayes_pls_golite062009
exopeptidase activity	0.960517137038552	bayes_pls_golite062009
binding	0.456088952797852	bayes_pls_golite062009
carboxypeptidase activity	0.389857234977383	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: