YRC Public Data Repository - Protein Structure Prediction

Protein:	OMPF_ECOLI
Organism:	Escherichia coli
Length:	362 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for OMPF_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|74311487, gi\|... - gi\|74311487\|ref\|YP_309906.1\| outer membrane protein F [Shigella sonnei Ss046], gi\|73854964\|gb\|AAZ876...	246.0	[0..1]	[362..1]
gi\|26107356, gi\|... - gi\|26246956\|ref\|NP_752996.1\| outer membrane protein F [Escherichia coli CFT073], gi\|26107356\|gb\|AAN7... gi\|115512271, gi... - gi\|117623147\|ref\|YP_852060.1\| outer membrane protein F [Escherichia coli APEC O1], gi\|115512271\|gb\|A... gi\|227884105, gi... - gi\|227884105\|ref\|ZP_04001910.1\| outer membrane porin 1a (Ia;b;F) [Escherichia coli 83972], gi\|227838... gi\|218364603, gi... - gi\|218557834\|ref\|YP_002390747.1\| outer membrane protein F [Escherichia coli S88], gi\|218364603\|emb\|C... gi\|190907631, gi... - gi\|75241004\|ref\|ZP_00724893.1\| COG3203: Outer membrane protein (porin) [Escherichia coli F11], gi\|19... gi\|218688772, gi... - gi\|218688772\|ref\|YP_002396984.1\| outer membrane protein F [Escherichia coli ED1a], gi\|218426336\|emb\|... gi\|91210031, gi\|... - gi\|91210031\|ref\|YP_540017.1\| outer membrane protein F [Escherichia coli UTI89], gi\|91071605\|gb\|ABE06... gi\|110342718, gi... - gi\|110641126\|ref\|YP_668856.1\| outer membrane protein F [Escherichia coli 536], gi\|110342718\|gb\|ABG68...	245.0	[0..1]	[362..1]
gi\|124499412, gi... - gi\|124530125\|ref\|ZP_01700895.1\| porin, Gram-negative type [Escherichia coli B], gi\|124499412\|gb\|EAY4... gi\|75512085, gi\|... - gi\|75512085\|ref\|ZP_00734670.1\| COG3203: Outer membrane protein (porin) [Escherichia coli 53638], gi\|... gi\|170020669, gi... - gi\|170020669\|ref\|YP_001725623.1\| outer membrane protein F [Escherichia coli ATCC 8739], gi\|169755597... gi\|75195119, gi\|... - gi\|75195119\|ref\|ZP_00705189.1\| COG3203: Outer membrane protein (porin) [Escherichia coli HS], gi\|157...	245.0	[0..1]	[362..1]
gi\|15830266, gi\|... - gi\|15830266\|ref\|NP_309039.1\| outer membrane protein F [Escherichia coli O157:H7 str. Sakai], gi\|1336... gi\|208737950, gi... - gi\|208822465\|ref\|ZP_03262784.1\| outer membrane protein F [Escherichia coli O157:H7 str. EC4042], gi\|... gi\|208815065, gi... - gi\|208815065\|ref\|ZP_03256244.1\| outer membrane protein F [Escherichia coli O157:H7 str. EC4045], gi\|... gi\|195939656 - gi\|195939656\|ref\|ZP_03085038.1\| outer membrane protein F [Escherichia coli O157:H7 str. EC4024] gi\|168787361, gi... - gi\|189372618\|gb\|EDU91034.1\| outer membrane protein F [Escherichia coli O157:H7 str. EC869], gi\|16878... gi\|254792129, gi... - gi\|254792129\|ref\|YP_003076966.1\| outer membrane porin 1a (Ia;b;F) [Escherichia coli O157:H7 str. TW1... gi\|209774708, gi... - pir\|\|B85619 outer membrane protein 1a (Ia,b,F) [imported] - Escherichia coli (strain O157:H7, substr... gi\|15800790, gi\|... - gi\|15800790\|ref\|NP_286804.1\| outer membrane protein F [Escherichia coli O157:H7 EDL933], gi\|12514104... gi\|217322812, gi... - gi\|217326591\|ref\|ZP_03442675.1\| outer membrane protein F [Escherichia coli O157:H7 str. TW14588], gi... gi\|15830266, gi\|... - gi\|15830266\|ref\|NP_309039.1\| outer membrane protein 1a [Escherichia coli O157:H7], gi\|13360471\|dbj\|B... gi\|209397832, gi... - gi\|209397832\|ref\|YP_002269601.1\| outer membrane protein F [Escherichia coli O157:H7 str. EC4115], gi... gi\|189355938, gi... - gi\|189355938\|gb\|EDU74357.1\| outer membrane protein F [Escherichia coli O157:H7 str. EC4401], gi\|1687... gi\|168751195, gi... - gi\|188014714\|gb\|EDU52836.1\| outer membrane protein F [Escherichia coli O157:H7 str. EC4113], gi\|1687... gi\|188998774, gi... - gi\|188998774\|gb\|EDU67760.1\| outer membrane protein F [Escherichia coli O157:H7 str. EC4076], gi\|1687... gi\|168776215, gi... - gi\|187768345\|gb\|EDU32189.1\| outer membrane protein F [Escherichia coli O157:H7 str. EC4196], gi\|1687... gi\|168769927, gi... - gi\|189361116\|gb\|EDU79535.1\| outer membrane protein F [Escherichia coli O157:H7 str. EC4486], gi\|1687... gi\|168762931, gi... - gi\|189366797\|gb\|EDU85213.1\| outer membrane protein F [Escherichia coli O157:H7 str. EC4501], gi\|1687...	245.0	[0..1]	[362..1]
gi\|81241695, gi\|... - gi\|82777547\|ref\|YP_403896.1\| outer membrane protein F [Shigella dysenteriae Sd197], gi\|81241695\|gb\|A...	244.0	[0..1]	[362..1]
gi\|24051202, gi\|... - gi\|24112338\|ref\|NP_706848.1\| outer membrane protein F [Shigella flexneri 2a str. 301], gi\|24051202\|g... gi\|30062464, gi\|... - gi\|30062464\|ref\|NP_836635.1\| outer membrane protein F [Shigella flexneri 2a str. 2457T], gi\|30040710... gi\|82544671, gi\|... - gi\|82544671\|ref\|YP_408618.1\| outer membrane protein F [Shigella boydii Sb227], gi\|81246082\|gb\|ABB667...	244.0	[0..1]	[362..1]
gi\|75189345 - gi\|75189345\|ref\|ZP_00702612.1\| COG3203: Outer membrane protein (porin) [Escherichia coli E24377A] gi\|83586317 - gi\|83586317\|ref\|ZP_00924952.1\| COG3203: Outer membrane protein (porin) [Escherichia coli 101-1]	238.0	[0..2]	[362..3]
gi\|1552809 - gi\|1552809\|gb\|AAB08661.1\| outer pore protein E precursor [Escherichia coli]	238.0	[0..2]	[362..3]

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Predicted Domain #1

Region A:
Residues: [1-362]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMKRNILAVI VPALLVAGTA NAAEIYNKDG NKVDLYGKAV GLHYFSKGNG ENSYGGNGDM  60
   61 TYARLGFKGE TQINSDLTGY GQWEYNFQGN NSEGADAQTG NKTRLAFAGL KYADVGSFDY 120
  121 GRNYGVVYDA LGYTDMLPEF GGDTAYSDDF FVGRVGGVAT YRNSNFFGLV DGLNFAVQYL 180
  181 GKNERDTARR SNGDGVGGSI SYEYEGFGIV GAYGAADRTN LQEAQPLGNG KKAEQWATGL 240
  241 KYDANNIYLA ANYGETRNAT PITNKFTNTS GFANKTQDVL LVAQYQFDFG LRPSIAYTKS 300
  301 KAKDVEGIGD VDLVNYFEVG ATYYFNKNMS TYVDYIINQI DSDNKLGVGS DDTVAVGIVY 360
  361 QF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	57.0
Match:	1hxuA
Description:	Porin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transporter activity	4.15398171369398	bayes_pls_golite062009
substrate-specific transporter activity	2.43332676180972	bayes_pls_golite062009
transmembrane transporter activity	1.99898520864149	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	1.37880749517427	bayes_pls_golite062009
ion transmembrane transporter activity	0.9810521942815	bayes_pls_golite062009
porin activity	0.896682978257159	bayes_pls_golite062009
cation transmembrane transporter activity	0.89213734347785	bayes_pls_golite062009
metal ion transmembrane transporter activity	0.70757821289609	bayes_pls_golite062009
binding	0.643879907209189	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	0.60516455096546	bayes_pls_golite062009
di-, tri-valent inorganic cation transmembrane transporter activity	0.17491456011246	bayes_pls_golite062009
lipid transporter activity	0.10911346172326	bayes_pls_golite062009
protein binding	0.0112080975548029	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: