YRC Public Data Repository - Protein Structure Prediction

Protein:	MALT_ECOLI
Organism:	Escherichia coli
Length:	901 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MALT_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|46916437, gi\|... - gi\|54303009\|ref\|YP_133002.1\| transcriptional regulator MalT [Photobacterium profundum SS9], gi\|46916...	302.0	[0..1]	[899..1]
gi\|90411221, gi\|... - gi\|90411221\|ref\|ZP_01219233.1\| transcriptional regulator MalT [Photobacterium profundum 3TCK], gi\|90...	301.0	[0..1]	[899..1]
MALT_VIBVU - HTH-type transcriptional regulator MalT OS=Vibrio vulnificus (strain CMCP6) GN=malT PE=3 SV=1 MALT_VIBVU - HTH-type transcriptional regulator malT OS=Vibrio vulnificus GN=malT PE=3 SV=1	298.0	[0..1]	[899..1]
MALT_VIBVY - HTH-type transcriptional regulator MalT OS=Vibrio vulnificus (strain YJ016) GN=malT PE=3 SV=1	298.0	[0..1]	[899..1]
gi\|194435809, gi... - gi\|83588717\|ref\|ZP_00927341.1\| COG2909: ATP-dependent transcriptional regulator [Escherichia coli 10...	297.0	[0..1]	[901..1]
gi\|606353\|gb\|AAA... - CG Site No. 526; alternate name malA [Escherichia coli] gi\|606353, gi\|146717 - gi\|606353\|gb\|AAA58216.1\| CG Site No. 526; alternate name malA [Escherichia coli], gi\|146717\|gb\|AAA83...	297.0	[0..1]	[901..1]
MALT_SHIBS - HTH-type transcriptional regulator MalT OS=Shigella boydii serotype 4 (strain Sb227) GN=malT PE=3 SV...	296.0	[0..1]	[901..1]
MALT_ECO24 - HTH-type transcriptional regulator MalT OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=malT...	296.0	[0..1]	[901..1]
gi\|254795334, gi... - gi\|254795334\|ref\|YP_003080171.1\| fused conserved protein, DNA-binding transcriptional activator, mal... gi\|192957946, gi... - gi\|75237020\|ref\|ZP_00721076.1\| COG2909: ATP-dependent transcriptional regulator [Escherichia coli E1... gi\|191167317, gi... - gi\|75229572\|ref\|ZP_00716115.1\| COG2909: ATP-dependent transcriptional regulator [Escherichia coli B7... gi\|168747103, gi... - gi\|188018381\|gb\|EDU56503.1\| maltose regulon activator MalT [Escherichia coli O157:H7 str. EC4113], g... gi\|189369920, gi... - gi\|189369920\|gb\|EDU88336.1\| maltose regulon activator MalT [Escherichia coli O157:H7 str. EC4501], g... gi\|189359095, gi... - gi\|189359095\|gb\|EDU77514.1\| maltose regulon activator MalT [Escherichia coli O157:H7 str. EC4401], g... gi\|168772688, gi... - gi\|187771503\|gb\|EDU35347.1\| maltose regulon activator MalT [Escherichia coli O157:H7 str. EC4196], g... gi\|168765767, gi... - gi\|189364677\|gb\|EDU83096.1\| maltose regulon activator MalT [Escherichia coli O157:H7 str. EC4486], g... MALT_ECO8A - HTH-type transcriptional regulator MalT OS=Escherichia coli O8 (strain IAI1) GN=malT PE=3 SV=1 gi\|217322171, gi... - gi\|217325950\|ref\|ZP_03442034.1\| transcriptional regulator MalT [Escherichia coli O157:H7 str. TW1458... MALT_ECOLU - HTH-type transcriptional regulator MalT OS=Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) GN=m... MALT_ECO55 - HTH-type transcriptional regulator MalT OS=Escherichia coli (strain 55989 / EAEC) GN=malT PE=3 SV=1 MALT_ECO57 - HTH-type transcriptional regulator MalT OS=Escherichia coli O157:H7 GN=malT PE=3 SV=1 gi\|189374536, gi... - gi\|189374536\|gb\|EDU92952.1\| maltose regulon activator MalT [Escherichia coli O157:H7 str. EC869], gi... gi\|168779503, gi... - gi\|189002532\|gb\|EDU71518.1\| maltose regulon activator MalT [Escherichia coli O157:H7 str. EC4076], g... gi\|208726488, gi... - gi\|208806687\|ref\|ZP_03249024.1\| transcriptional regulator MalT [Escherichia coli O157:H7 str. EC4206... gi\|195934907 - gi\|195934907\|ref\|ZP_03080289.1\| transcriptional regulator MalT [Escherichia coli O157:H7 str. EC4024... gi\|25301092, gi\|... - pir\|\|D86007 positive regulator of mal regulon [imported] - Escherichia coli (strain O157:H7, substra... gi\|208819408, gi... - gi\|208819408\|ref\|ZP_03259728.1\| transcriptional regulator MalT [Escherichia coli O157:H7 str. EC4042... gi\|208812898, gi... - gi\|208812898\|ref\|ZP_03254227.1\| transcriptional regulator MalT [Escherichia coli O157:H7 str. EC4045... MALT_ECOSE - HTH-type transcriptional regulator MalT OS=Escherichia coli (strain SE11) GN=malT PE=3 SV=1 gi\|15803923, gi\|... - gi\|15803923\|ref\|NP_289959.1\| transcriptional regulator MalT [Escherichia coli O157:H7 EDL933], gi\|12... gi\|15833514, gi\|... - gi\|15833514\|ref\|NP_312287.1\| transcriptional regulator MalT [Escherichia coli O157:H7 str. Sakai], g... MALT_ECO5E - HTH-type transcriptional regulator MalT OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=malT P...	295.0	[0..1]	[901..1]
gi\|194414888, gi... - gi\|75211785\|ref\|ZP_00711849.1\| COG2909: ATP-dependent transcriptional regulator [Escherichia coli B1...	295.0	[0..1]	[901..1]

Back

Predicted Domain #1

Region A:
Residues: [1-422]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLIPSKLSRP VRLDHTVVRE RLLAKLSGAN NFRLALITSP AGYGKTTLIS QWAAGKNDIG  60
   61 WYSLDEGDNQ QERFASYLIA AVQQATNGHC AICETMAQKR QYASLTSLFA QLFIELAEWH 120
  121 SPLYLVIDDY HLITNPVIHE SMRFFIRHQP ENLTLVVLSR NLPQLGIANL RVRDQLLEIG 180
  181 SQQLAFTHQE AKQFFDCRLS SPIEAAESSR ICDDVSGWAT ALQLIALSAR QNTHSAHKSA 240
  241 RRLAGINASH LSDYLVDEVL DNVDLATRHF LLKSAILRSM NDALITRVTG EENGQMRLEE 300
  301 IERQGLFLQR MDDTGEWFCY HPLFGNFLRQ RCQWELAAEL PEIHRAAAES WMAQGFPSEA 360
  361 IHHALAAGDA LMLRDILLNH AWSLFNHSEL SLLEESLKAL PWDSLLENPQ LVLLQAWLMQ 420
  421 SQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	13.69897
Match:	1z6tA
Description:	Structure of the apoptotic protease-activating factor 1 bound to ADP
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [423-809]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HRYGEVNTLL ARAEHEIKDI REDTMHAEFN ALRAQVAIND GNPDEAERLA KLALEELPPG  60
   61 WFYSRIVATS VLGEVLHCKG ELTRSLALMQ QTEQMARQHD VWHYALWSLI QQSEILFAQG 120
  121 FLQTAWETQE KAFQLINEQH LEQLPMHEFL VRIRAQLLWA WARLDEAEAS ARSGIEVLSS 180
  181 YQPQQQLQCL AMLIQCSLAR GDLDNARSQL NRLENLLGNG KYHSDWISNA NKVRVIYWQM 240
  241 TGDKAAAANW LRHTAKPEFA NNHFLQGQWR NIARAQILLG EFEPAEIVLE ELNENARSLR 300
  301 LMSDLNRNLL LLNQLYWQAG RKSDAQRVLL DALKLANRTG FISHFVIEGE AMAQQLRQLI 360
  361 QLNTLPELEQ HRAQRILREI NQHHRHK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	16.69897
Match:	1hz4A
Description:	Transcription factor MalT domain III
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.38012107359817	bayes_pls_golite062009
protein binding	0.90942498397011	bayes_pls_golite062009
transcription regulator activity	0.802322336220332	bayes_pls_golite062009
nucleic acid binding	0.41617031570549	bayes_pls_golite062009
DNA binding	0.29647638972446	bayes_pls_golite062009

Predicted Domain #3

Region A:
Residues: [810-901]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FAHFDENFVE RLLNHPEVPE LIRTSPLTQR EWQVLGLIYS GYSNEQIAGE LEVAATTIKT  60
   61 HIRNLYQKLG VAHRQDAVQH AQQLLKMMGY GV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	15.39794
Match:	1yioA
Description:	Crystallographic structure of response regulator StyR from Pseudomonas fluorescens
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	4.3783822692838	bayes_pls_golite062009
DNA binding	2.98242537415469	bayes_pls_golite062009
nucleic acid binding	2.90897931927895	bayes_pls_golite062009
transcription factor activity	2.57346479183384	bayes_pls_golite062009
binding	1.861833300221	bayes_pls_golite062009
two-component response regulator activity	1.47327435257738	bayes_pls_golite062009
signal transducer activity	1.437458964114	bayes_pls_golite062009
molecular transducer activity	1.437458964114	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions:

Predicted functions: