YRC Public Data Repository - Protein Structure Prediction

Protein:	GUAD_ECOLI
Organism:	Escherichia coli
Length:	439 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GUAD_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|91212261, gi\|... - gi\|91212261\|ref\|YP_542247.1\| guanine deaminase [Escherichia coli UTI89], gi\|91073835\|gb\|ABE08716.1\| ...	332.0	[0..1]	[439..41]
gi\|26249296, gi\|... - gi\|26249296\|ref\|NP_755336.1\| guanine deaminase [Escherichia coli CFT073], gi\|26109703\|gb\|AAN81906.1\|...	332.0	[0..1]	[439..41]
gi\|887833 - gi\|887833\|gb\|AAA83064.1\| ORF_o439	331.0	[0..1]	[439..1]
gi\|253974697, gi... - gi\|254162796\|ref\|YP_003045904.1\| guanine deaminase [Escherichia coli B str. REL606], gi\|253974697\|gb... gi\|251786143, gi... - gi\|251786143\|ref\|YP_003000447.1\| hypothetical protein B21_02678 [Escherichia coli BL21], gi\|24237841... gi\|83587721 - gi\|83587721\|ref\|ZP_00926348.1\| COG0402: Cytosine deaminase and related metal-dependent hydrolases [E... gi\|254289556, gi... - gi\|254289556\|ref\|YP_003055304.1\| guanine deaminase [Escherichia coli BL21(DE3)], gi\|253978863\|gb\|ACT...	331.0	[0..1]	[439..1]
gi\|218366645, gi... - gi\|218559876\|ref\|YP_002392789.1\| guanine deaminase [Escherichia coli S88], gi\|218366645\|emb\|CAR04399... gi\|237706474, gi... - gi\|237706474\|ref\|ZP_04536955.1\| guanine deaminase [Escherichia sp. 3_2_53FAA], gi\|226899514\|gb\|EEH85... gi\|75239227 - gi\|75239227\|ref\|ZP_00723200.1\| COG0402: Cytosine deaminase and related metal-dependent hydrolases [E... gi\|115514239, gi... - gi\|117625115\|ref\|YP_854103.1\| guanine deaminase [Escherichia coli APEC O1], gi\|115514239\|gb\|ABJ02314...	331.0	[0..1]	[439..1]
gi\|75234611 - gi\|75234611\|ref\|ZP_00718942.1\| COG0402: Cytosine deaminase and related metal-dependent hydrolases [E... gi\|75515334 - gi\|75515334\|ref\|ZP_00737518.1\| COG0402: Cytosine deaminase and related metal-dependent hydrolases [E...	331.0	[0..1]	[439..1]
gi\|209760658, gi... - pir\|\|D91098 hypothetical protein ECs3756 [imported] - Escherichia coli (strain O157:H7, substrain R... gi\|15833010, gi\|... - gi\|15833010\|ref\|NP_311783.1\| guanine deaminase [Escherichia coli O157:H7], gi\|13363228\|dbj\|BAB37179.... gi\|15833010, gi\|... - gi\|15833010\|ref\|NP_311783.1\| guanine deaminase [Escherichia coli O157:H7 str. Sakai], gi\|13363228\|db...	331.0	[0..1]	[439..1]
gi\|75212503 - gi\|75212503\|ref\|ZP_00712527.1\| COG0402: Cytosine deaminase and related metal-dependent hydrolases [E... gi\|75187599 - gi\|75187599\|ref\|ZP_00700866.1\| COG0402: Cytosine deaminase and related metal-dependent hydrolases [E... gi\|218696479, gi... - gi\|218696479\|ref\|YP_002404146.1\| guanine deaminase [Escherichia coli 55989], gi\|218353211\|emb\|CAU991... gi\|218428573, gi... - gi\|218691009\|ref\|YP_002399221.1\| guanine deaminase [Escherichia coli ED1a], gi\|218428573\|emb\|CAR0950... gi\|75258482 - gi\|75258482\|ref\|ZP_00729904.1\| COG0402: Cytosine deaminase and related metal-dependent hydrolases [E... gi\|218362200, gi... - gi\|218555432\|ref\|YP_002388345.1\| guanine deaminase [Escherichia coli IAI1], gi\|218362200\|emb\|CAQ9981... gi\|75230856 - gi\|75230856\|ref\|ZP_00717314.1\| COG0402: Cytosine deaminase and related metal-dependent hydrolases [E... gi\|209913597, gi... - gi\|209920338\|ref\|YP_002294422.1\| guanine deaminase [Escherichia coli SE11], gi\|209913597\|dbj\|BAG7867...	330.0	[0..1]	[439..1]
gi\|12517407, gi\|... - gi\|15803420\|ref\|NP_289453.1\| guanine deaminase [Escherichia coli O157:H7 EDL933], gi\|12517407\|gb\|AAG... gi\|25329019 - pir\|\|H85943 hypothetical protein ygfP [imported] - Escherichia coli (strain O157:H7, substrain EDL9...	330.0	[0..1]	[439..1]
gi\|75196835 - gi\|75196835\|ref\|ZP_00706905.1\| COG0402: Cytosine deaminase and related metal-dependent hydrolases [E...	330.0	[0..1]	[439..1]

Back

Predicted Domain #1

Region A:
Residues: [1-439]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMSGEHTLKA VRGSFIDVTR TIDNPEEIAS ALRFIEDGLL LIKQGKVEWF GEWENGKHQI  60
   61 PDTIRVRDYR GKLIVPGFVD THIHYPQSEM VGAYGEQLLE WLNKHTFPTE RRYEDLEYAR 120
  121 EMSAFFIKQL LRNGTTTALV FGTVHPQSVD ALFEAASHIN MRMIAGKVMM DRNAPDYLLD 180
  181 TAESSYHQSK ELIERWHKNG RLLYAITPRF APTSSPEQMA MAQRLKEEYP DTWVHTHLCE 240
  241 NKDEIAWVKS LYPDHDGYLD VYHQYGLTGK NCVFAHCVHL EEKEWDRLSE TKSSIAFCPT 300
  301 SNLYLGSGLF NLKKAWQKKV KVGMGTDIGA GTTFNMLQTL NEAYKVLQLQ GYRLSAYEAF 360
  361 YLATLGGAKS LGLDDLIGNF LPGKEADFVV MEPTATPLQQ LRYDNSVSLV DKLFVMMTLG 420
  421 DDRSIYRTYV DGRLVYERN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	60.0
Match:	2oodA
Description:	No description for 2oodA was found.

Predicted functions:

Term	Confidence	Notes
guanine deaminase activity	3.78802420851729	bayes_pls_golite062009
hydrolase activity	3.06979421893431	bayes_pls_golite062009
adenine deaminase activity	1.87830487335945	bayes_pls_golite062009
deaminase activity	1.79186203771221	bayes_pls_golite062009
catalytic activity	1.70199291046899	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	1.60895003474033	bayes_pls_golite062009
dihydropyrimidinase activity	1.51712244686012	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	0.787370269329878	bayes_pls_golite062009
nucleic acid binding	0.629962267754185	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	0.573107361273483	bayes_pls_golite062009
binding	0.514083592777841	bayes_pls_golite062009
transcription regulator activity	0.506159010274668	bayes_pls_golite062009
DNA binding	0.462348875991261	bayes_pls_golite062009
peptidase activity	0.370872229900721	bayes_pls_golite062009
dihydroorotase activity	0.203044795244555	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: