YRC Public Data Repository - Protein Structure Prediction

Protein:	GNTR_ECOLI
Organism:	Escherichia coli
Length:	331 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GNTR_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|20807285 - gi\|20807285\|ref\|NP_622456.1\| Transcriptional regulator [Thermoanaerobacter tengcongensis MB4] gi\|20807285, gi\|... - gi\|20807285\|ref\|NP_622456.1\| transcriptional regulator [Thermoanaerobacter tengcongensis MB4], gi\|20...	364.0	[0..6]	[331..2]
gi\|167038831, gi... - gi\|167038831\|ref\|YP_001661816.1\| periplasmic binding protein/LacI transcriptional regulator [Thermoa... gi\|242258204, gi... - gi\|242258204\|ref\|ZP_04803030.1\| transcriptional regulator, LacI family [Thermoanaerobacter sp. X513]...	363.0	[0..6]	[330..3]
gi\|89209818, gi\|... - gi\|89209818\|ref\|ZP_01188212.1\| regulatory protein, LacI:Periplasmic binding protein/LacI transcripti...	355.0	[0..5]	[330..2]
PURR_VIBVU - HTH-type transcriptional repressor PurR OS=Vibrio vulnificus GN=purR PE=3 SV=1 PURR_VIBVY - HTH-type transcriptional repressor PurR OS=Vibrio vulnificus (strain YJ016) GN=purR PE=3 SV=1 PURR_VIBVU - HTH-type transcriptional repressor PurR OS=Vibrio vulnificus (strain CMCP6) GN=purR PE=3 SV=1	353.0	[0..6]	[331..2]
gi\|37200774, gi\|... - gi\|37676233\|ref\|NP_936629.1\| transcriptional regulator [Vibrio vulnificus YJ016], gi\|37200774\|dbj\|BA...	351.0	[0..6]	[331..2]
gi\|166856755, gi... - gi\|76795834\|ref\|ZP_00778205.1\| regulatory protein, LacI:Periplasmic binding protein/LacI transcripti... gi\|241903736, gi... - gi\|241903736\|ref\|ZP_04788455.1\| transcriptional regulator, LacI family [Thermoanaerobacter brockii s...	351.0	[0..6]	[330..2]

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Predicted Domain #1

Region A:
Residues: [1-331]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKKKRPVLQD VADRVGVTKM TVSRFLRNPE QVSVALRGKI AAALDELGYI PNRAPDILSN  60
   61 ATSRAIGVLL PSLTNQVFAE VLRGIESVTD AHGYQTMLAH YGYKPEMEQE RLESMLSWNI 120
  121 DGLILTERTH TPRTLKMIEV AGIPVVELMD SKSPCLDIAV GFDNFEAARQ MTTAIIARGH 180
  181 RHIAYLGARL DERTIIKQKG YEQAMLDAGL VPYSVMVEQS SSYSSGIELI RQARREYPQL 240
  241 DGVFCTNDDL AVGAAFECQR LGLKVPDDMA IAGFHGHDIG QVMEPRLASV LTPRERMGSI 300
  301 GAERLLARIR GESVTPKMLD LGFTLSPGGS I

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	94.39794
Match:	1zvvA
Description:	Crystal structure of a ccpa-crh-dna complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	3.03730517010624	bayes_pls_golite062009
DNA binding	2.13752511265098	bayes_pls_golite062009
transcription factor activity	2.10452652023643	bayes_pls_golite062009
nucleic acid binding	2.05471649974481	bayes_pls_golite062009
binding	1.58080550382179	bayes_pls_golite062009
RNA polymerase II transcription factor activity	0.29966985317584	bayes_pls_golite062009
sequence-specific DNA binding	0.20324889750334	bayes_pls_golite062009
signal transducer activity	0.11302624216037	bayes_pls_golite062009
molecular transducer activity	0.11302624216037	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: