YRC Public Data Repository - Protein Structure Prediction

Protein:	GLPQ_ECOLI
Organism:	Escherichia coli
Length:	358 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GLPQ_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|75187028 - gi\|75187028\|ref\|ZP_00700295.1\| COG0584: Glycerophosphoryl diester phosphodiesterase [Escherichia col...	346.0	[0..1]	[358..14]
gi\|83588225 - gi\|83588225\|ref\|ZP_00926850.1\| COG0584: Glycerophosphoryl diester phosphodiesterase [Escherichia col...	346.0	[0..1]	[358..14]
gi\|75230372 - gi\|75230372\|ref\|ZP_00716862.1\| COG0584: Glycerophosphoryl diester phosphodiesterase [Escherichia col... gi\|75211650 - gi\|75211650\|ref\|ZP_00711729.1\| COG0584: Glycerophosphoryl diester phosphodiesterase [Escherichia col... gi\|75259705 - gi\|75259705\|ref\|ZP_00731007.1\| COG0584: Glycerophosphoryl diester phosphodiesterase [Escherichia col... gi\|75238030 - gi\|75238030\|ref\|ZP_00722035.1\| COG0584: Glycerophosphoryl diester phosphodiesterase [Escherichia col...	345.0	[0..1]	[358..14]
gi\|75196280 - gi\|75196280\|ref\|ZP_00706350.1\| COG0584: Glycerophosphoryl diester phosphodiesterase [Escherichia col...	345.0	[0..1]	[358..14]
gi\|75243053 - gi\|75243053\|ref\|ZP_00726759.1\| COG0584: Glycerophosphoryl diester phosphodiesterase [Escherichia col... gi\|227887296, gi... - gi\|227887296\|ref\|ZP_04005101.1\| glycerophosphodiester phosphodiesterase [Escherichia coli 83972], gi...	345.0	[0..1]	[358..14]
gi\|75177962 - gi\|75177962\|ref\|ZP_00698024.1\| COG0584: Glycerophosphoryl diester phosphodiesterase [Shigella boydii...	344.0	[0..1]	[358..14]
gi\|157157861, gi... - gi\|157157861\|ref\|YP_001463588.1\| glycerophosphodiester phosphodiesterase [Escherichia coli E24377A],... gi\|115513556, gi... - gi\|117624432\|ref\|YP_853345.1\| glycerophosphodiester phosphodiesterase [Escherichia coli APEC O1], gi... gi\|254593532, gi... - gi\|254794132\|ref\|YP_003078969.1\| periplasmic glycerophosphodiester phosphodiesterase [Escherichia co... gi\|226901080, gi... - gi\|237704714\|ref\|ZP_04535195.1\| glycerophosphoryl diester phosphodiesterase [Escherichia sp. 3_2_53F... gi\|189368294, gi... - gi\|189368294\|gb\|EDU86710.1\| glycerophosphoryl diester phosphodiesterase GlpQ [Escherichia coli O157:... gi\|168749644, gi... - gi\|188016052\|gb\|EDU54174.1\| glycerophosphoryl diester phosphodiesterase GlpQ [Escherichia coli O157:... gi\|13362594, gi\|... - gi\|15832378\|ref\|NP_311151.1\| glycerophosphodiester phosphodiesterase [Escherichia coli O157:H7], gi\|... gi\|209765498, gi... - pir\|\|F85863 glycerophosphodiester phosphodiesterase [imported] - Escherichia coli (strain O157:H7, s... gi\|15802788, gi\|... - gi\|15802788\|ref\|NP_288815.1\| glycerophosphodiester phosphodiesterase [Escherichia coli O157:H7 EDL93... gi\|218559155, gi... - gi\|218559155\|ref\|YP_002392068.1\| glycerophosphodiester phosphodiesterase [Escherichia coli S88], gi\|... gi\|217320071, gi... - gi\|217327704\|ref\|ZP_03443787.1\| glycerophosphoryl diester phosphodiesterase [Escherichia coli O157:H... gi\|209919691, gi... - gi\|209919691\|ref\|YP_002293775.1\| glycerophosphodiester phosphodiesterase [Escherichia coli SE11], gi... gi\|209396883, gi... - gi\|209396883\|ref\|YP_002271648.1\| glycerophosphoryl diester phosphodiesterase [Escherichia coli O157:... gi\|218352577, gi... - gi\|218695845\|ref\|YP_002403512.1\| glycerophosphodiester phosphodiesterase [Escherichia coli 55989], g... gi\|189379005, gi... - gi\|189379005\|gb\|EDU97421.1\| glycerophosphoryl diester phosphodiesterase GlpQ [Escherichia coli O157:... gi\|168780090, gi... - gi\|189002050\|gb\|EDU71036.1\| glycerophosphoryl diester phosphodiesterase GlpQ [Escherichia coli O157:... gi\|13362594, gi\|... - gi\|15832378\|ref\|NP_311151.1\| glycerophosphodiester phosphodiesterase [Escherichia coli O157:H7 str. ... gi\|187771119, gi... - gi\|187771119\|gb\|EDU34963.1\| glycerophosphoryl diester phosphodiesterase GlpQ [Escherichia coli O157:... gi\|189362772, gi... - gi\|189362772\|gb\|EDU81191.1\| glycerophosphoryl diester phosphodiesterase GlpQ [Escherichia coli O157:... gi\|208821497, gi... - gi\|208821497\|ref\|ZP_03261817.1\| glycerophosphoryl diester phosphodiesterase [Escherichia coli O157:H... gi\|208735600, gi... - gi\|208814323\|ref\|ZP_03255652.1\| glycerophosphoryl diester phosphodiesterase [Escherichia coli O157:H... gi\|208726351, gi... - gi\|208806550\|ref\|ZP_03248887.1\| glycerophosphoryl diester phosphodiesterase [Escherichia coli O157:H... gi\|195935615 - gi\|195935615\|ref\|ZP_03080997.1\| glycerophosphodiester phosphodiesterase [Escherichia coli O157:H7 st...	344.0	[0..1]	[358..1]
gi\|110806208, gi... - gi\|110806208\|ref\|YP_689728.1\| glycerophosphodiester phosphodiesterase [Shigella flexneri 5 str. 8401...	344.0	[0..1]	[358..1]
gi\|82544517, gi\|... - gi\|82544517\|ref\|YP_408464.1\| glycerophosphodiester phosphodiesterase [Shigella boydii Sb227], gi\|812... gi\|187427577, gi... - gi\|187730585\|ref\|YP_001881070.1\| glycerophosphoryl diester phosphodiesterase GlpQ [Shigella boydii C...	343.0	[0..1]	[358..1]
gi\|91073105, gi\|... - gi\|91211531\|ref\|YP_541517.1\| glycerophosphodiester phosphodiesterase [Escherichia coli UTI89], gi\|91...	343.0	[0..1]	[358..1]

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Predicted Domain #1

Region A:
Residues: [1-358]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLTLKNLSM AIMMSTIVMG SSAMAADSNE KIVIAHRGAS GYLPEHTLPA KAMAYAQGAD  60
   61 YLEQDLVMTK DDNLVVLHDH YLDRVTDVAD RFPDRARKDG RYYAIDFTLD EIKSLKFTEG 120
  121 FDIENGKKVQ TYPGRFPMGK SDFRVHTFEE EIEFVQGLNH STGKNIGIYP EIKAPWFHHQ 180
  181 EGKDIAAKTL EVLKKYGYTG KDDKVYLQCF DADELKRIKN ELEPKMGMEL NLVQLIAYTD 240
  241 WNETQQKQPD GSWVNYNYDW MFKPGAMKQV AEYADGIGPD YHMLIEETSQ PGNIKLTGMV 300
  301 QDAQQNKLVV HPYTVRSDKL PEYTPDVNQL YDALYNKAGV NGLFTDFPDK AVKFLNKE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	93.69897
Match:	1ydyA
Description:	Crystal structure of periplasmic glycerophosphodiester phosphodiesterase from Escherichia coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
glycerophosphodiester phosphodiesterase activity	4.27697417361287	bayes_pls_golite062009
phosphoric diester hydrolase activity	3.6633363681844	bayes_pls_golite062009
phospholipase activity	3.3535603060637	bayes_pls_golite062009
phosphoric ester hydrolase activity	2.89024275707278	bayes_pls_golite062009
phospholipase C activity	2.81479108775786	bayes_pls_golite062009
inositol or phosphatidylinositol phosphodiesterase activity	2.13368269358874	bayes_pls_golite062009
phosphoinositide phospholipase C activity	2.13368269358874	bayes_pls_golite062009
hydrolase activity	1.41001330359992	bayes_pls_golite062009
lipase activity	1.30779031242608	bayes_pls_golite062009
catalytic activity	1.22328099675039	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	1.21202479488854	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: